Lowest Prices
We partner with the top bus & train carriers to bring you the best deals.
Best Travel Options
We help you find & compare the best buses & trains in one place.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
Journey Information
There is one daily bus from Brussels to Prague. Traveling by bus from Brussels to Prague usually takes around 11 hours and 55 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 446 mi (719 km) |
| Shortest duration | 11h 55m |
| Cheapest price | US$67.97 |
| Trips per day | 1 |
| Most frequent service | RegioJet |
| Bus lines | 1 |
What bus companies travel from Brussels to Prague?
There is one intercity bus company available to search and book on Wanderu that operates from Brussels to Prague. RegioJet is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| RegioJet | 1 | 11h 55m | US$75.03 |
Book RegioJet from Brussels to Prague from US$68. There are 1 RegioJet schedules from Brussels to Prague and you can expect on average to pay for a RegioJet ticket to Prague. In Brussels, RegioJet departs to Prague from Gare du Midi and no other station. In Prague, RegioJet arrives at Prague Florenc Bus Station and no other station.
An average trip on RegioJet from Brussels to Prague takes 11 hours and 55 minutes .
On weekends, RegioJet offers 1 trip per day and you could expect to pay for a weekend getaway trip to Prague.
Frequently Asked Questions
The bus takes an average of 11 hours and 55 minutes to cover the 719 kilometers from Brussels to Prague. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from Brussels to Prague. It leaves the station in Brussels at 6:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Brussels
The center of European activities, Brussels is a cosmopolitan hub that features many cultural elements, making it one of the top destinations for international travelers. Sitting at the heart of Brussels is the famous Grand-Place, a world heritage site that boasts many nearby Gothic and Baroque architectural marvels. During the holiday season, the square hosts the Winter Wonders light show, as well as a giant Christmas tree. If you enjoy museums, don’t miss out on the Musical Instruments Museum, which is housed in an Art Nouveau building. Featuring as many as 1,200 instruments from around the world, the museum is every music fan’s dream. If you want to go on a shopping spree while in Brussels, head for the Les Galeries Royales Saint-Hubert, which is housed in a stunning Renaissance-style arcade.
Brussels is the home to many Michelin-starred restaurants, and its food scene is among the top-rated in the country. For those wishing to enjoy a contemporary twist on Belgian classics, head towards La Quincaillerie. If seafood is your go-to, Noordzee Mer du Nord will definitely satisfy your palate.
Brussels’ three main rail stations are Brussels-South, Brussels-Central, and Brussels-North, all of which are the busiest in the country. Gare du Midi, located in the Brussels-South station, is the main hub for bus travel in and out of Brussels. The city is served by several airports, the most prominent of which is the Brussels-National Airport, located 10 miles east of the city.
Prague
With storied churches and beautiful castles, Prague was once the hidden gem of Europe, and it has now revealed its beauty to the world. Prague’s prized landmark is the majestic Prague Castle, which is the largest castle complex in the world. The castle is an amalgamation of many different architectural styles, making it a very special destination to visit. You might even get to see the president of Czechia as well, since it is his office! If you simply want to stroll around and enjoy the vibe of the city, head for the Old Town Square, which has seen very few changes since its conception in the 12th century. If you are not afraid of a little hiking, head to Petrin Hill, which is one of the largest green areas in the city. The area also houses the Rose Garden and Seminary Garden, featuring more than 2,100 trees.
Prague’s food scene is not as well-known as other famous cities’, but the local dishes such as knedlíky or bramboráky will pleasantly surprise you. La Degustation Boheme Bourgeoise is a Michelin-starred restaurant that offers amazing Czech dishes. For local beers, don’t hesitate to check out U Medvídku.
Praha hlavní nádraží is the largest international train station in Prague and it’s located right in the heart of the city. Not too far from the train station is Prague’s central bus station. The principal airport in the city is the Václav Havel Airport Prague.
Station Information
Where does the bus leave from in Brussels?
Main departure station: Gare du Midi
Also known as Brussels-South railway station, the Gare du Midi is the primary train station serving Brussels. The station is technically located in Saint-Gilles, a city south of Brussels, but the Gare du Midi metro stop connects travelers to all of Brussels' sights and attractions. Many high-speed train services, including international train lines, run through the Gare du Midi. Brussels is connected to the famous Eurostar line through this station, along with Thalys and Deutsche Bahn lines. The large indoor station includes many retail shops, restaurants, and services like information desks and restrooms.
All bus stations in Brussels:
Gare du Midi
Where does the bus arrive in Prague?
Image credit: Elekes Andor
Link to image attributionMain arrival station: Prague Florenc Bus Station
Prague Florenc Central Bus Station is the city's largest and busiest bus station. The station complex is fully equipped with all the modern amenities you could ask for, including information services, luggage storage, public toilets, restaurants, and shops. Bus lines including FlixBus and RegioJet stop at the station, and Prague's central train station is less than 2km away for connections to rail travel. Right outside the bus station, you'll find the Florenc Metro stop, a hotel, several restaurants, and excellent shopping.
Bus stations in Prague:
Prague Florenc Bus Station
Get around town with Moovit
Need a return trip from Prague to Brussels?
Search Bus Tickets
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free and with no additional fees. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
Book buses and trains on the go with the Wanderu app.
Download our app and snag the best travel deals across North America & Europe.Learn more