Search Gainesville, FL to Knoxville bus tickets



Gainesville, FL to Knoxville bus - cost & duration

Cheapest price$200.22
Fastest time13h 15m
Trips per day1
bus carriers1
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How to book cheap bus tickets from Gainesville, FL to Knoxville

The best way to get deals on bus tickets from Gainesville to Knoxville is by booking earlier. Based on the last 30 days, the cheapest average bus fares from Gainesville to Knoxville were $226.73. By booking 1 days out, tickets are on average $3.31 cheaper than those that are booked last minute.

How long is the bus ride from Gainesville, FL to Knoxville?

The distance between Gainesville and Knoxville is approximately 445.88 miles, or 717.40 kilometers. The average travel time for a bus between these two cities is around 15 hours and 49 minutes, although the absolute fastest you could get there is 13 hours and 15 minutes.

Looking for ways to pass the time? Most buses are equipped with Wi-Fi, which means you can stream music, browse social media or get some work done during your ride. That said, in case your bus has a spotty signal, or is among the few without Wi-Fi, we also recommend downloading TV shows and movies to your mobile device in advance of your trip. That way the ride will fly by whatever the Wi-Fi situation.

What is the busiest time to travel by bus from Gainesville to Knoxville?

The busiest time of the week for travel from Gainesville, FL to Knoxville by bus is on Sunday. When planning to travel around this time, tickets should be booked well in advance as they may sell out. Friday is when the fewest number of bus tickets are sold. If you’re looking for a little extra space, the bus departing at this time is the least likely to be crowded.

Greyhound from Gainesville, FL to Knoxville has the most daily schedules

On average there is 1 bus trip per day. Greyhound has the most options for departures from Gainesville, FL to Knoxville, with an average of 1 trip per day and 4 monthly trips. One bus carrier currently travels from Gainesville to Knoxville. Of the 1 trip there are 0 trips that are direct routes with no transfers.

1 carriers offer Gainesville, FL to Knoxville bus trips


Book Greyhound from Gainesville to Knoxville from $184.30. There are 1 Greyhound schedules from Gainesville to Knoxville and you can expect on average to pay $223.42 for a Greyhound ticket to Knoxville. In Gainesville, Greyhound departs to Knoxville from Bus Terminal - 101 NE 23rd Ave and no other station. In Knoxville, Greyhound arrives at Bus Terminal - 100 E Magnolia Ave and no other station.

An average trip on Greyhound from Gainesville to Knoxville takes 15 hours and 49 minutes, while the fastest available Greyhound trip will get you to Knoxville in 13 hours and 15 minutes,

On weekends, Greyhound offers 2 trips per day and you could expect to pay $210.16 for a weekend getaway trip to Knoxville.

Power outlet
Air conditioning
Avg. Time
15h 49m
Avg. Price

Plan your next adventure

Depending on the bus line you travel with, your options include one station that has bus departures from Gainesville. Most bus trips to Knoxville will depart from:
  • Bus Terminal - 101 NE 23rd Ave
Bus trips arrive in Knoxville at 1 stations, depending on which bus line you are traveling with. These are the main bus stations in Knoxville for trips arriving from Gainesville:
  • Bus Terminal - 100 E Magnolia Ave