|Fastest time||21h 0m|
|Trips per day||2|
Book Jefferson Lines from Humansville to La Crosse from $197.31. There are 2 Jefferson Lines schedules from Humansville to La Crosse and you can expect on average to pay $215.83 for a Jefferson Lines ticket to La Crosse. In Humansville, Jefferson Lines departs to La Crosse from 117 S Ohio St and no other station. In La Crosse, Jefferson Lines arrives at 314 Jay St and 1 other station.
An average trip on Jefferson Lines from Humansville to La Crosse takes 21 hours and 18 minutes, while the fastest available Jefferson Lines trip will get you to La Crosse in 21 hours and 0 minutes,
On weekends, Jefferson Lines offers 2 trips per day and you could expect to pay $227.79 for a weekend getaway trip to La Crosse.