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Journey Information
There are 2 intercity buses per day from Harrisburg to Knoxville. Traveling by bus from Harrisburg to Knoxville usually takes around 20 hours and 40 minutes, but the fastest Greyhound bus can make the trip in 19 hours and 20 minutes.
| Distance | 484 mi (780 km) |
| Shortest duration | 19h 20m |
| Cheapest price | US$162.98 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
What bus companies travel from Harrisburg to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Harrisburg to Knoxville. Greyhound is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 2 | 20h 40m | US$171.97 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Harrisburg to Knoxville every day, with the average journey taking around 20 hours and 40 minutes to complete. Bus tickets for Greyhound trips to Knoxville usually start from US$163.
Frequently Asked Questions
The bus takes an average of 20 hours and 40 minutes to cover the 780 kilometers from Harrisburg to Knoxville. However, the fastest bus only takes 19 hours and 20 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 8:00pm and the last bus leaves at 11:00pm. To see the times for all buses from Harrisburg to Knoxville, enter your specific travel dates in the search bar.
City Information
Harrisburg
As the capital city of Pennsylvania, Harrisburg offers numerous historic buildings with impressive architecture that will leave you in awe. Among the most impressive ones is the state’s Capitol Complex itself. With a dome that reminisces St. Peter’s Basilica in Rome, the building features as many as 475 rooms filled with exquisite artworks and statues. History fans should also consider visiting the State Museum of Pennsylvania, which follows the history of the state from the beginning of time to this day. Another must-see destination is the National Civil War Museum, which is one of the largest museums dedicated to the Civil War. If too many history lessons stress you out, a cruise along the Susquehanna River on the Pride of the Susquehanna Riverboat will definitely help you unwind.
Harrisburg’s grilled dishes are some of the most famous staples in the city, and among the best establishments is Progress Grill, which has been serving customers since the late 1940s. For some really creative pizzas, The Pizza Grille will be a good choice.
The Harrisburg Transportation Center is the central hub for intercity travel. At the lower level, you can catch a bus by Greyhound, Jefferson Lines or Fullington Trailways to other Pennsylvanian cities such as Allentown and Philadelphia. Travelers can also take Amtrak trains to popular destinations like New York and Philadelphia on a daily basis. The city’s principal airport is Harrisburg International Airport, which is located in Middletown, southeast of the city.
Station Information
Where does the bus leave from in Harrisburg?
Main departure station: Harrisburg Transportation Center
Most buses depart from the main station in Harrisburg.
All bus stations in Harrisburg:
Harrisburg Transportation Center
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Harrisburg arrive at one main station in Knoxville.
Bus stations in Knoxville:
Knoxville Bus Station
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