|Fastest time||11h 55m|
|Trips per day||4|
Book Greyhound from Knoxville to St Louis from $150.59. There are 4 Greyhound schedules from Knoxville to St Louis and you can expect on average to pay $171.53 for a Greyhound ticket to St Louis. In Knoxville, Greyhound departs to St Louis from Bus Terminal - 100 E Magnolia Ave and no other station. In St Louis, Greyhound arrives at Gateway Station - 430 S 15th St and no other station.
An average trip on Greyhound from Knoxville to St Louis takes 13 hours and 23 minutes, while the fastest available Greyhound trip will get you to St Louis in 11 hours and 55 minutes,
On weekends, Greyhound offers 4 trips per day and you could expect to pay $186.26 for a weekend getaway trip to St Louis.