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Journey Information
There are 3 intercity buses per day from Knoxville to St Louis. Traveling by bus from Knoxville to St Louis usually takes around 17 hours and 40 minutes, but the fastest Greyhound bus can make the trip in 17 hours and 15 minutes.
| Distance | 391 mi (629 km) |
| Shortest duration | 17h 15m |
| Cheapest price | $86.23 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
How much is a bus ticket from Knoxville to St Louis?
$101.22 is the average price of a bus ticket from Knoxville to St Louis. While it’s on the pricier side for a bus ticket, taking the bus is still a cheaper alternative to flying. It’s easy to find a bus ticket at this price or lower when you use Wanderu to book your trip online in advance of your travel date.
Monthly average prices
What bus companies travel from Knoxville to St Louis?
There is one intercity bus company available to search and book on Wanderu that operates from Knoxville to St Louis. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 3 | 17h 41m | $122.83 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Knoxville to St Louis every day, with the average journey taking around 17 hours and 41 minutes to complete. Bus tickets for Greyhound trips to St Louis usually start from $85.
Frequently Asked Questions
The bus takes an average of 17 hours and 40 minutes to cover the 629 kilometers from Knoxville to St Louis. However, the fastest bus only takes 17 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
"With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go."
The first bus leaves at 6:00pm and the last bus leaves at 10:00pm. To see the times for all buses from Knoxville to St Louis, enter your specific travel dates in the search bar.
City Information
St Louis
Image credit: Unsplash
Image credit: Unsplash
Image credit: Unsplash
St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.
Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.
Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.
The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.
Station Information
Where does the bus leave from in Knoxville?
Main departure station: Knoxville Bus Station
Most buses depart from the main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
Where does the bus arrive in St Louis?
Main arrival station: Gateway Station - 430 S 15th St
All buses from Knoxville arrive at one main station in St Louis.
Bus stations in St Louis:
Gateway Station - 430 S 15th St
Get around town with Moovit
Need a return trip from St Louis to Knoxville?
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