5.0
Pros: Everything was great! Cons: None! Tips: Try it!
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There are usually 2 daily train trips from Chicago to Harrisburg.
Coach | Train | |
|---|---|---|
Avg. Price | Avg. PriceUS$125.67 | Avg. PriceUS$228.56 |
Daily Trips | Daily Trips6 | Daily Trips2 |
Duration | Duration16h 49m | Duration20h 34m |
There are 8 intercity coaches per day from Chicago to Harrisburg. Traveling by coach from Chicago to Harrisburg usually takes around 16 hours and 45 minutes, but the fastest Greyhound coach can make the trip in 15 hours and 15 minutes.
| Distance | 570 mi (917 km) |
| Shortest duration | 15h 15m |
| Cheapest price | US$70.97 |
| Trips per day | 3 |
| Most frequent service | FlixBus US |
| Coach lines | 2 |

Average score for coaches from Chicago to Harrisburg
(Based on 1 ratings and reviews)
5.0
Pros: Everything was great! Cons: None! Tips: Try it!
Bus tickets for a trip from Chicago to Harrisburg cost US$92.73 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Over the next four weeks, the average price of bus tickets from Chicago to Harrisburg is expected to be between US$83 and US$175. The cheapest day to travel in the next month is 13 November 2025, when tickets are available for 13 November 2025. The cheapest bus tickets available in the next week start at just US$83.
To save money on bus tickets, buy them as early as possible. Bus carriers usually charge higher ticket prices the closer you book to the date of travel. Book your ticket at least 13 days in advance to save up to US$73.87.
There are two bus lines that have daily service from Chicago to Harrisburg that you can compare and book on Wanderu. Of these two carriers, FlixBus US usually offers more choice, with 6 scheduled trips per day.
| Coach | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 6 | 16h 57m | US$123.50 |
| Greyhound | 3 | 16h 41m | US$105.17 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 6 trips per day from Chicago to Harrisburg, and the average ticket for this route costs only .
Greyhound is the largest nationwide coach carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Chicago to Harrisburg every day, with the average journey taking around 16 hours and 41 minutes to complete. Bus tickets for Greyhound trips to Harrisburg usually start from US$71.
The coach takes an average of 16 hours and 45 minutes to cover the 570 miles from Chicago to Harrisburg. However, the fastest coach only takes 15 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual coach may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for coach travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Thursday is typically the least busy day for coach travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
The first coach leaves at 04:00 and the last coach leaves at 19:00. To see the times for all coaches from Chicago to Harrisburg, enter your specific travel dates in the search bar.
There are 8 scheduled coaches that travel from Chicago to Harrisburg every day, so you have a decent number of options to choose from. This includes 3 direct coaches, where you can stay on the same coach without having to transfer to a connecting coach at any point during your trip.
Need more travel options? Consider taking the train from Chicago to Harrisburg; ticket prices start at US$109.00.



Known for its innovative architecture, cultural contributions to jazz and house music, and of course that irresistible deep-dish pizza, the many sights and experiences in Chicago make it one of the best urban vacation destinations for millennials and a top destination in Illinois.
You can't beat the views of the city and Lake Michigan from the SkyDeck in the Willis Tower; at over 1,300 feet, this is the highest observation deck in the U.S. Snap that classic selfie with the Bean in Millennium Park, then wander the many museums in nearby Grant Park. Navy Pier is a popular tourist hotspot for its parks, restaurants, and attractions right on Lake Michigan, and baseball fans will find paradise in Wrigleyville, home to the Chicago Cubs' Wrigley Field and sports bars galore.
Chicago's enormous parks offer plentiful opportunities for outdoor activities in gorgeous urban settings. Many companies offer kayak rentals or boat tours on the Chicago River, with special tours running on Saint Patrick's Day, when the entire river is dyed green. When you’re ready to buy some souvenirs from your epic trip, hit the big brand stores on the Magnificent Mile, or shop local in neighborhoods like Andersonville and Wicker Park. And don't miss the chance to laugh until you cry at The Second City comedy theater, famous for launching the careers of comedians like Tina Fey and Stephen Colbert.
Chicago is one of the biggest transportation hubs in the Midwest, and provides easy access to nearby destinations ideal for day trips, as well as international travel from two airports. Thanks to plenty of bus and train stations throughout the city, getting to the Windy City is a breeze.



As the capital city of Pennsylvania, Harrisburg offers numerous historic buildings with impressive architecture that will leave you in awe. Among the most impressive ones is the state’s Capitol Complex itself. With a dome that reminisces St. Peter’s Basilica in Rome, the building features as many as 475 rooms filled with exquisite artworks and statues. History fans should also consider visiting the State Museum of Pennsylvania, which follows the history of the state from the beginning of time to this day. Another must-see destination is the National Civil War Museum, which is one of the largest museums dedicated to the Civil War. If too many history lessons stress you out, a cruise along the Susquehanna River on the Pride of the Susquehanna Riverboat will definitely help you unwind.
Harrisburg’s grilled dishes are some of the most famous staples in the city, and among the best establishments is Progress Grill, which has been serving customers since the late 1940s. For some really creative pizzas, The Pizza Grille will be a good choice.
The Harrisburg Transportation Center is the central hub for intercity travel. At the lower level, you can catch a bus by Greyhound, Jefferson Lines or Fullington Trailways to other Pennsylvanian cities such as Allentown and Philadelphia. Travelers can also take Amtrak trains to popular destinations like New York and Philadelphia on a daily basis. The city’s principal airport is Harrisburg International Airport, which is located in Middletown, southeast of the city.

Image credit: Jeramey Jannene
Link to image attributionCoaches to Harrisburg leave from 3 stations in Chicago.
Bus Station - 630 W Harrison St
Dan Ryan Bus Station
Chicago Train Station Bus Stop
All coaches from Chicago arrive at one main station in Harrisburg.
Harrisburg Transportation Center

With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.