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Journey Information
There are 10 intercity buses per day from Rome to Prague. Traveling by bus from Rome to Prague usually takes around 21 hours and 41 minutes, but the fastest FlixBus bus can make the trip in 18 hours and 50 minutes.
| Distance | 572 mi (921 km) |
| Shortest duration | 18h 50m |
| Cheapest price | €42.72 |
| Trips per day | 1 |
| Most frequent service | FlixBus |
| Bus lines | 2 |
How much is a bus ticket from Rome to Prague?
€78.45 is the average price of a bus ticket from Rome to Prague. While it’s on the pricier side for a bus ticket, taking the bus is still a cheaper alternative to flying. It’s easy to find a bus ticket at this price or lower when you use Wanderu to book your trip online in advance of your travel date.
Monthly average prices
What bus companies travel from Rome to Prague?
There are two bus lines that have daily service from Rome to Prague that you can compare and book on Wanderu. Of these two carriers, FlixBus usually offers more choice, with 10 scheduled trips per day.
First launched in Germany in 2013, FlixBus has become one of the largest intercity bus companies in Europe. Its fleet travels through nearly every country in Europe, including the U.K. FlixBus operates an average of 10 trips from Rome to Prague, and usually makes the trip in about 21 hours and 43 minutes. On your trip, you'll enjoy Wi-Fi and live GPS, as well as restrooms, air conditioning, and power outlets.
Book RegioJet from Rome to Prague from €49. There are 2 trips per day offered by RegioJet from Rome to Prague and you can expect on average to pay for a RegioJet ticket to Prague. In Rome, RegioJet departs to Prague from Largo Guido Mazzoni . In Prague, RegioJet arrives at Praha hl.n. and one other station.
An average trip on RegioJet from Rome to Prague takes 20 hours and 30 minutes , while the fastest available RegioJet trip will get you to Prague in 18 hours and 50 minutes .
On weekends, RegioJet offers 2 trips per day. A one way ticket costs for a weekend trip to Prague.
Frequently Asked Questions
Our bus partners have implemented several different policies to keep you safe during the COVID-19 pandemic. From limiting vehicle capacity to enhancing cleaning protocols and upgrading air filters, bus carriers are committed to maintaining a safe environment. For details on what each company is doing to ensure their fleet remains safe for travel, click here.
Although masks are no longer required on public transportation, we stand behind CDC guidelines that encourage passengers to wear a mask over their nose and mouth while on the bus or in stations.
Please visit our COVID-19 Travel Guide for more information on all carrier policies and the latest travel advisories issued by every U.S. state, Canadian province, and European country.
The bus takes an average of 21 hours and 41 minutes to cover the 921 kilometers from Rome to Prague. However, the fastest bus only takes 18 hours and 50 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
"Because many passengers travel from Rome to Prague at the beginning of the work week, Monday is usually the busiest day for buses. If you are planning to travel on a Monday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet."
The first bus leaves at 00:00 and the last bus leaves at 21:00. To see the times for all buses from Rome to Prague, enter your specific travel dates in the search bar.
There are 10 scheduled buses that travel from Rome to Prague every day, so you have a decent number of options to choose from. However, only one of these is a direct bus. With direct service, you do not have to transfer onto a different bus at any point during your trip. Direct buses also tend to be significantly faster, which is worth bearing in mind as you compare the available options.
Need more travel options? Consider taking the train from Rome to Prague; ticket prices start at €73.37.
City Information
Rome
Rome is a city rich in cultural heritage, as well as one of the most romantic destinations in Europe. To fully understand the city’s extraordinary history, visitors should take the time to visit the Capitoline Museums, where the collections include hundreds of sculptures as well as the Capitoline Wolf, the symbol of Rome itself. The famous Trevi’s Fountain is also on the must-see list of many travelers. Boasting an amazing baroque design with mythological motifs, the fountain is one of the most photogenic spots in the city, and it is located near the principal shopping area. If you wish to check out some of the city’s most iconic structures, head over to the Sistine Chapel, which houses the famous fresco by Michelangelo.
Rome is every foodie’s heaven. As you explore the city’s food scene, don’t hesitate to take the chance to try out a local specialty, artichokes. The best place to try these out is at Nonna Betta. For those who want to try the famous Roma coffee, Caffe Sant'Eustachio might be the right spot.
The principal train station in Rome is the Termini station. The main bus station is Roma Tiburtina. The city’s air services are fulfilled by three airports: Leonardo da Vinci International Airport, Rome Ciampino Airport, and Roma-Urbe, of which the Leonardo da Vinci International Airport is the largest.
Prague
With storied churches and beautiful castles, Prague was once the hidden gem of Europe, and it has now revealed its beauty to the world. Prague’s prized landmark is the majestic Prague Castle, which is the largest castle complex in the world. The castle is an amalgamation of many different architectural styles, making it a very special destination to visit. You might even get to see the president of Czechia as well, since it is his office! If you simply want to stroll around and enjoy the vibe of the city, head for the Old Town Square, which has seen very few changes since its conception in the 12th century. If you are not afraid of a little hiking, head to Petrin Hill, which is one of the largest green areas in the city. The area also houses the Rose Garden and Seminary Garden, featuring more than 2,100 trees.
Prague’s food scene is not as well-known as other famous cities’, but the local dishes such as knedlíky or bramboráky will pleasantly surprise you. La Degustation Boheme Bourgeoise is a Michelin-starred restaurant that offers amazing Czech dishes. For local beers, don’t hesitate to check out U Medvídku.
Praha hlavní nádraží is the largest international train station in Prague and it’s located right in the heart of the city. Not too far from the train station is Prague’s central bus station. The principal airport in the city is the Václav Havel Airport Prague.
Station Information
Where does the bus leave from in Rome?
Image credit: CAPTAIN RAJU
Link to image attributionMain departure station: Largo Guido Mazzoni
Rome's main long-distance coach station, known as Autostazione Tiburtina, is located on Largo Guido Mazzoni in the northeast of the city. The modern, state-of-the-art facility has several small food outlets, restrooms, and left luggage facilities. Coach companies like FlixBus and RegioJet operate routes from Tiburtina to destinations including Venice and Prague. It can be accessed via the city's metro line B and is just a short walk to Roma Tiburtina railway station. Several hotels, bars, and restaurants line the nearby Via Tiburtina for the perfect welcome to the Eternal City.
All bus stations in Rome:
Largo Guido Mazzoni
Via Vincenzo Giudice
Ciampino Airport
Where does the bus arrive in Prague?
Image credit: Elekes Andor
Link to image attributionMain arrival station: Prague Florenc Bus Station
Prague Florenc Central Bus Station is the city's largest and busiest bus station. The station complex is fully equipped with all the modern amenities you could ask for, including information services, luggage storage, public toilets, restaurants, and shops. Bus lines including FlixBus and RegioJet stop at the station, and Prague's central train station is less than 2km away for connections to rail travel. Right outside the bus station, you'll find the Florenc Metro stop, a hotel, several restaurants, and excellent shopping.
Bus stations in Prague:
Prague Florenc Bus Station
Main Railway Station
Prague Anděl Ostrovského 34/1
Tomíčkova
Praha hl.n.
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