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Harrisburg to St Louis bus

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Harrisburg - St Louis Bus Timetable

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Journey Information

There are 5 intercity buses per day from Harrisburg to St Louis. Traveling by bus from Harrisburg to St Louis usually takes around 19 hours and 58 minutes, but the fastest Greyhound bus can make the trip in 17 hours and 5 minutes.

Distance719 mi (1156 km)
Shortest duration17h 5m
Cheapest priceUS$113.99
Trips per day4
Most frequent serviceGreyhound
Bus lines1

What bus companies travel from Harrisburg to St Louis?

There is one intercity bus company available to search and book on Wanderu that operates from Harrisburg to St Louis. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.

BusDaily TripsAvg. TimeAvg. Price
Greyhound519h 58mUS$143.99
  • Greyhound is the largest nationwide coach carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 5 bus trips from Harrisburg to St Louis every day, with the average journey taking around 19 hours and 58 minutes to complete. Bus tickets for Greyhound trips to St Louis usually start from US$114.

Frequently Asked Questions

The bus takes an average of 19 hours and 58 minutes to cover the 1156 kilometers from Harrisburg to St Louis. However, the fastest bus only takes 17 hours and 5 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

"Travel trends tend to vary greatly for bus trips from Harrisburg to St Louis."

The first bus leaves at 00:00 and the last bus leaves at 23:00. To see the times for all buses from Harrisburg to St Louis, enter your specific travel dates in the search bar.

There are 5 scheduled buses that travel from Harrisburg to St Louis every day, so you have a decent number of options to choose from. This includes 4 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.

Need more travel options? Consider taking the train from Harrisburg to St Louis; ticket prices start at US$167.00.

City Information

Harrisburg

As the capital city of Pennsylvania, Harrisburg offers numerous historic buildings with impressive architecture that will leave you in awe. Among the most impressive ones is the state’s Capitol Complex itself. With a dome that reminisces St. Peter’s Basilica in Rome, the building features as many as 475 rooms filled with exquisite artworks and statues. History fans should also consider visiting the State Museum of Pennsylvania, which follows the history of the state from the beginning of time to this day. Another must-see destination is the National Civil War Museum, which is one of the largest museums dedicated to the Civil War. If too many history lessons stress you out, a cruise along the Susquehanna River on the Pride of the Susquehanna Riverboat will definitely help you unwind.

Harrisburg’s grilled dishes are some of the most famous staples in the city, and among the best establishments is Progress Grill, which has been serving customers since the late 1940s. For some really creative pizzas, The Pizza Grille will be a good choice.

The Harrisburg Transportation Center is the central hub for intercity travel. At the lower level, you can catch a bus by Greyhound, Jefferson Lines or Fullington Trailways to other Pennsylvanian cities such as Allentown and Philadelphia. Travelers can also take Amtrak trains to popular destinations like New York and Philadelphia on a daily basis. The city’s principal airport is Harrisburg International Airport, which is located in Middletown, southeast of the city.

St Louis

St. Louis, MO - STL-0

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St. Louis, MO - STL-1

Image credit: Unsplash

St. Louis, MO - STL-2

Image credit: Unsplash

St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.

Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.

Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.

The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.

Station Information

Where does the bus leave from in Harrisburg?

Main departure station: Harrisburg Transportation Center

Most buses depart from the main station in Harrisburg.

All bus stations in Harrisburg:

  • Harrisburg Transportation Center

Where does the bus arrive in St Louis?

Main arrival station: Gateway Station - 430 S 15th St

All buses from Harrisburg arrive at one main station in St Louis.

Bus stations in St Louis:

  • Gateway Station - 430 S 15th St

Get around town with Moovit

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