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Journey Information
There are 25 intercity buses per day from Prague to Brussels. Traveling by bus from Prague to Brussels usually takes around 18 hours and 52 minutes, but the fastest FlixBus bus can make the trip in 14 hours and 50 minutes.
| Distance | 446 mi (719 km) |
| Shortest duration | 14h 50m |
| Cheapest price | €35.14 |
| Trips per day | 2 |
| Most frequent service | FlixBus |
| Bus lines | 1 |
What bus companies travel from Prague to Brussels?
There is one intercity bus company available to search and book on Wanderu that operates from Prague to Brussels. FlixBus connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus | 25 | 18h 52m | €82.98 |
First launched in Germany in 2013, FlixBus has become one of the largest intercity bus companies in Europe. Its fleet travels through nearly every country in Europe, including the U.K. FlixBus operates an average of 25 trips from Prague to Brussels, and usually makes the trip in about 18 hours and 52 minutes. On your trip, you'll enjoy Wi-Fi and live GPS, as well as restrooms, air conditioning, and power outlets.
Frequently Asked Questions
The bus takes an average of 18 hours and 52 minutes to cover the 446 miles from Prague to Brussels. However, the fastest bus only takes 14 hours and 50 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Travelers prefer riding the bus on Saturday to enjoy the weekend in Brussels. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
The first bus leaves at 2:00am and the last bus leaves at 11:00pm. To see the times for all buses from Prague to Brussels, enter your specific travel dates in the search bar.
City Information
Prague
With storied churches and beautiful castles, Prague was once the hidden gem of Europe, and it has now revealed its beauty to the world. Prague’s prized landmark is the majestic Prague Castle, which is the largest castle complex in the world. The castle is an amalgamation of many different architectural styles, making it a very special destination to visit. You might even get to see the president of Czechia as well, since it is his office! If you simply want to stroll around and enjoy the vibe of the city, head for the Old Town Square, which has seen very few changes since its conception in the 12th century. If you are not afraid of a little hiking, head to Petrin Hill, which is one of the largest green areas in the city. The area also houses the Rose Garden and Seminary Garden, featuring more than 2,100 trees.
Prague’s food scene is not as well-known as other famous cities’, but the local dishes such as knedlíky or bramboráky will pleasantly surprise you. La Degustation Boheme Bourgeoise is a Michelin-starred restaurant that offers amazing Czech dishes. For local beers, don’t hesitate to check out U Medvídku.
Praha hlavní nádraží is the largest international train station in Prague and it’s located right in the heart of the city. Not too far from the train station is Prague’s central bus station. The principal airport in the city is the Václav Havel Airport Prague.
Brussels
The center of European activities, Brussels is a cosmopolitan hub that features many cultural elements, making it one of the top destinations for international travelers. Sitting at the heart of Brussels is the famous Grand-Place, a world heritage site that boasts many nearby Gothic and Baroque architectural marvels. During the holiday season, the square hosts the Winter Wonders light show, as well as a giant Christmas tree. If you enjoy museums, don’t miss out on the Musical Instruments Museum, which is housed in an Art Nouveau building. Featuring as many as 1,200 instruments from around the world, the museum is every music fan’s dream. If you want to go on a shopping spree while in Brussels, head for the Les Galeries Royales Saint-Hubert, which is housed in a stunning Renaissance-style arcade.
Brussels is the home to many Michelin-starred restaurants, and its food scene is among the top-rated in the country. For those wishing to enjoy a contemporary twist on Belgian classics, head towards La Quincaillerie. If seafood is your go-to, Noordzee Mer du Nord will definitely satisfy your palate.
Brussels’ three main rail stations are Brussels-South, Brussels-Central, and Brussels-North, all of which are the busiest in the country. Gare du Midi, located in the Brussels-South station, is the main hub for bus travel in and out of Brussels. The city is served by several airports, the most prominent of which is the Brussels-National Airport, located 10 miles east of the city.
Station Information
Where does the bus leave from in Prague?
Image credit: Elekes Andor
Link to image attributionMain departure station: Prague Florenc Bus Station
Prague Florenc Central Bus Station is the city's largest and busiest bus station. The station complex is fully equipped with all the modern amenities you could ask for, including information services, luggage storage, public toilets, restaurants, and shops. Bus lines including FlixBus and RegioJet stop at the station, and Prague's central train station is less than 2km away for connections to rail travel. Right outside the bus station, you'll find the Florenc Metro stop, a hotel, several restaurants, and excellent shopping.
All bus stations in Prague:
Prague Florenc Bus Station
Prague Anděl Ostrovského 34/1
Aviatická 1017/2
Main Railway Station
Zličín
Central Bus Station
kancelář u nástupiště č. 6
Tomíčkova
Hradčanská
Where does the bus arrive in Brussels?
Main arrival station: Gare du Midi
Also known as Brussels-South railway station, the Gare du Midi is the primary train station serving Brussels. The station is technically located in Saint-Gilles, a city south of Brussels, but the Gare du Midi metro stop connects travelers to all of Brussels' sights and attractions. Many high-speed train services, including international train lines, run through the Gare du Midi. Brussels is connected to the famous Eurostar line through this station, along with Thalys and Deutsche Bahn lines. The large indoor station includes many retail shops, restaurants, and services like information desks and restrooms.
All bus stations in Brussels:
Gare du Midi
Avenue Fonsny
Magnolialaan 1
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