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Journey Information
There are 6 intercity buses per day from Siena to Sant'Agnello. Traveling by bus from Siena to Sant'Agnello usually takes around 7 hours and 45 minutes, but the fastest FlixBus bus can make the trip in 7 hours and 32 minutes.
Distance | 243 mi (392 km) |
Shortest duration | 7h 32m |
Cheapest price | $24.81 |
Most frequent service | FlixBus |
Bus lines | 1 |
What bus companies travel from Siena to Sant'Agnello?
There is one intercity bus company available to search and book on Wanderu that operates from Siena to Sant'Agnello. FlixBus connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
Bus | Daily Trips | Avg. Time | Avg. Price |
---|---|---|---|
FlixBus | 6 | 7h 45m | $42.28 |
First launched in Germany in 2013, FlixBus has become one of the largest intercity bus companies in Europe. Its fleet travels through nearly every country in Europe, including the U.K. FlixBus operates an average of 6 trips from Siena to Sant'Agnello, and usually makes the trip in about 7 hours and 45 minutes. On your trip, you'll enjoy Wi-Fi and live GPS, as well as restrooms, air conditioning, and power outlets.
Frequently Asked Questions
Our bus partners have implemented several different policies to keep you safe during the COVID-19 pandemic. From limiting vehicle capacity to enhancing cleaning protocols and upgrading air filters, bus carriers are committed to maintaining a safe environment. For details on what each company is doing to ensure their fleet remains safe for travel, click here.
Although masks are no longer required on public transportation, we stand behind CDC guidelines that encourage passengers to wear a mask over their nose and mouth while on the bus or in stations.
Please visit our COVID-19 Travel Guide for more information on all carrier policies and the latest travel advisories issued by every U.S. state, Canadian province, and European country.
The bus takes an average of 7 hours and 45 minutes to cover the 243 miles from Siena to Sant'Agnello. However, the fastest bus only takes 7 hours and 32 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Tuesday is usually the day of the week when buses are busiest. If you are planning to travel on a Tuesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Friday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Friday ticket is the way to go.
The first bus leaves at 8:00am and the last bus leaves at 10:00am. To see the times for all buses from Siena to Sant'Agnello, enter your specific travel dates in the search bar.
City Information
Siena

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Set among the rolling hills of Tuscany, Siena is the provincial capital in central Italy. Siena has an extensive history, dating to the Etruscan era, although most of the town's growth didn't occur until the Middle Ages. Take a walk up one of the many surrounding hills to gain a birds' eye view of Siena, in many ways identical to how it looked in the medieval period.
The best way to appreciate the town is to embrace the Italian lifestyle, enjoying a coffee and people-watching in the Piazza del Campo. After this, visit the Duomo di Siena to view its Gothic exterior, intricate mosaic floor, and many of the preserved works of Catholic worship that lay inside.
After a long day of exploring, refuel with some mouthwatering local cuisine. Visit any of the authentic Sienese restaurants to try pici, a type of pasta, and make sure to sample at least one of the many famous desserts from the region.
Siena's central location in Italy makes it easy to access from major metropolises like Rome, Paris, or Barcelona. Ampugnano Airport is only 9 kilometers from the city, although Florence and Pisa airports offer more frequent flights with a wider choice of airlines. Frequent trains pass through Siena from several cities in Italy, and two bus lines operate between Florence and Siena.
Station Information
Where does the bus leave from in Siena?

Image credit: Vyacheslav Argenberg
Link to image attributionMain departure station: Piazza Carlo Rosselli
Siena FS is a bus terminal in the small town of Siena. The terminal is next to the main railway station and encompasses bus stops for various carriers like FlixBus. The train station is a large pale brick building with smaller bus stops nearby and shelters for various operators. Inside, you can find amenities such as ticket desks, kiosks, a cafe, and fast food restaurants at the bus station. Slightly further away are multiple bars, restaurants, a few hotels, and a Co-op supermarket, plus information about buses and trains inside the railway station.
All bus stations in Siena:
Piazza Carlo Rosselli
Stellino - Via Fiorentina 135
Viale Pietro Toselli
Where does the bus arrive in Sant'Agnello?
Main arrival station: Corso Italia 123
These are the two stations where buses may stop when they arrive in Sant'Agnello.
All bus stations in Sant'Agnello:
Corso Italia 123
Corso Italia 45
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