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San Diego to St Louis bus

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San Diego - St Louis Bus Schedule

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Journey Information

There are 13 intercity buses per day from San Diego to St Louis. Traveling by bus from San Diego to St Louis usually takes around 49 hours and 26 minutes, but the fastest FlixBus US bus can make the trip in 43 hours and 15 minutes.

Distance1561 mi (2512 km)
Shortest duration43h 15m
Cheapest price$180.44
Most frequent serviceFlixBus US
Bus lines1

How much is a bus ticket from San Diego to St Louis?

Bus tickets for a trip from San Diego to St Louis cost $181.20 on average. Bus tickets on this route can be a bit expensive due to the length of the trip. But even with a higher price tag, taking the bus is often more affordable than flying to St Louis. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.

Monthly avg. prices

$300$240$180$120$60AMJJASONDJFM
Taking the bus from San Diego to St Louis is usually cheapest in January, when the average ticket price is only $197. If you're planning to take the bus from San Diego to St Louis during February, keep in mind that bus ticket prices may be higher than usual, with an average price of $280. However, booking your trip in advance can help you score a ticket at a better price.

What bus companies travel from San Diego to St Louis?

There is one intercity bus company available to search and book on Wanderu that operates from San Diego to St Louis. FlixBus US connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US132d 1h 26m$379.15
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 13 trips per day from San Diego to St Louis, and the average ticket for this route costs only .

Frequently Asked Questions

The bus takes an average of 49 hours and 26 minutes to cover the 1561 miles from San Diego to St Louis. However, the fastest bus only takes 43 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Friday is the busiest travel day for buses as people head from San Diego to St Louis for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.

The first bus leaves at 6:00am and the last bus leaves at 6:00pm. To see the times for all buses from San Diego to St Louis, enter your specific travel dates in the search bar.

There are 13 scheduled buses that travel from San Diego to St Louis every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.

Need more travel options? Consider taking the train from San Diego to St Louis; ticket prices start at $229.00.

City Information

San Diego

San Diego is known as "America's Finest City" for its sunny weather, white-sand beaches, and dazzling attractions from Belmont Park to SeaWorld. San Diego's 70 miles of pristine beaches include such gems as Mission Beach, Pacific Beach, La Jolla Cove, and Coronado Beach. The city's strong surfing culture may even inspire you to rent a surfboard and catch the epic waves, bro.

Visitors can spend days getting lost in Balboa Park, a 1,200-acre cultural hub which features 16 museums, immaculate gardens, and the world-famous San Diego Zoo. The historic heart of the city, Old Town, showcases San Diego's heritage and ties to Mexican culture, while other sights like the USS Midway pay tribute to the city's military and maritime history. Leave time for some evening exploring, too! San Diego is rated the #1 best city for craft beer in America, so don't miss out on the bars in the Gaslamp Quarter: 16 walkable blocks packed with nightlife and young crowds.

Two airports, as well as many bus and train options, mean it is easy to get to San Diego from afar or from nearby cities like Tijuana, Los Angeles, Phoenix, and Las Vegas.

St Louis

St. Louis, MO - STL-0

Image credit: Unsplash

St. Louis, MO - STL-1

Image credit: Unsplash

St. Louis, MO - STL-2

Image credit: Unsplash

St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.

Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.

Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.

The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.

Station Information

Where does the bus leave from in San Diego?

Main departure station: 2728 Congress St (Old Town SD)

Buses to St Louis leave from 6 stations in San Diego.

All bus stations in San Diego:

  • 2728 Congress St (Old Town SD)

  • La Jolla - UC San Diego

  • Balboa Park - Presidents Way

  • SDSU - 5716 Hardy Ave

  • San Ysidro Transit Center

  • 789 W Harbor Dr - Seaport Village

Where does the bus arrive in St Louis?

Main arrival station: Saint Louis (Lambert Field)

These are the two stations where buses may stop when they arrive in St Louis.

All bus stations in St Louis:

  • Saint Louis (Lambert Field)

  • Gateway Station - 430 S 15th St

Get around town with Moovit

Find the best way to get to and from any station in St Louis by public transit, courtesy of Moovit. Search now

Need a return trip from St Louis to San Diego?

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