5.0
Pros: Worked out pretty well very convenient timing was perfect no delay as promised. Cons: So far so good. Tips: Keep the good work.
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There are 4 intercity buses per day from Fort Myers to Gainesville. Traveling by bus from Fort Myers to Gainesville usually takes around 8 hours and 30 minutes, but the fastest RedCoach Business bus can make the trip in 5 hours and 5 minutes.
| Distance | 210 mi (338 km) |
| Shortest duration | 5h 5m |
| Cheapest price | €42.79 |
| Trips per day | 1 |
| Most frequent service | FlixBus US |
| Bus lines | 4 |

Average score for buses from Fort Myers to Gainesville
(Based on 2 ratings and reviews)
5.0
Pros: Worked out pretty well very convenient timing was perfect no delay as promised. Cons: So far so good. Tips: Keep the good work.
Bus tickets for a trip from Fort Myers to Gainesville cost €53.51 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
There are 4 bus lines from Fort Myers to Gainesville available for you to search and compare on Wanderu. With 4 daily trips, FlixBus US usually has the most buses running on any given day. Here are some time and price comparisons for all the available options:
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 4 | 14h 22m | €81.58 |
| RedCoach Business | 1 | 5h 5m | €57.16 |
RedCoach First Class | 1 | 5h 5m | €67.32 |
| Tornado Bus | 1 | 6h 43m | €107.57 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 4 trips per day from Fort Myers to Gainesville, and the average ticket for this route costs only .
Book RedCoach Business from Fort Myers to Gainesville from €43. Typically there is one RedCoach Business schedule per day from Fort Myers to Gainesville and you can expect on average to pay for a RedCoach Business ticket to Gainesville. In Fort Myers, RedCoach Business departs to Gainesville from 5951 Enterprise Pkwy . In Gainesville, RedCoach Business arrives at 1956 Gale Lemerand Drive .
An average trip on RedCoach Business from Fort Myers to Gainesville takes 5 hours and 5 minutes .
On weekends, RedCoach Business offers 1 trip per day and you could expect to pay for a one way ticket for your weekend getaway trip to Gainesville.
Book RedCoach First Class from Fort Myers to Gainesville from €58. Typically there is one RedCoach First Class schedule per day from Fort Myers to Gainesville and you can expect on average to pay for a RedCoach First Class ticket to Gainesville. In Fort Myers, RedCoach First Class departs to Gainesville from 5951 Enterprise Pkwy . In Gainesville, RedCoach First Class arrives at 1956 Gale Lemerand Drive .
An average trip on RedCoach First Class from Fort Myers to Gainesville takes 5 hours and 5 minutes .
On weekends, RedCoach First Class offers 1 trip per day and you could expect to pay for a one way ticket for your weekend getaway trip to Gainesville.
The bus takes an average of 8 hours and 30 minutes to cover the 210 miles from Fort Myers to Gainesville. However, the fastest bus only takes 5 hours and 5 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Tuesday is usually the day of the week when buses are busiest. If you are planning to travel on a Tuesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Saturday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Saturday ticket is the way to go.
The first bus leaves at 10:00am and the last bus leaves at 6:00pm. To see the times for all buses from Fort Myers to Gainesville, enter your specific travel dates in the search bar.



Blessed with amazing natural landmarks and a vibrant cultural life, Gainesville offers a whole new Florida experience that is far from the decadence often associated with the state. If you wish to explore creative works made by local artists, head over to the Cade Museum for Creativity & Invention, which features great exhibitions that dive into the life of many inventors and entrepreneurs. Another great museum to visit is the Samuel P. Harn Museum of Art. For those who want to marvel at the city’s natural landmarks, go for a hiking trip along the trails of Alfred A. Ring Park, or the Barr Hammock Preserve.
Gainesville’s local favorite is the 4 Rivers Smokehouse, which offers delicious briskets. For some of the freshest local dishes, head over to Alpin Bistro.
The main bus station in Gainesville is the Greyhound Bus Terminal located on NE 23rd Ave, which welcomes buses from Miami, Fort Lauderdale, Houston and beyond. There is no rail service to Gainesville. However, the city is part of Amtrak’s network via the carrier’s Thruway bus service, which operates out of the same station. The main airport is the Gainesville Regional Airport, which lies in the northeast part of the city.
Buses to Gainesville leave from 3 stations in Fort Myers.
Ft Myers Bus Station
5951 Enterprise Pkwy
7-Eleven
Buses arrive in Gainesville at 4 stations, depending on which bus line you are traveling with.
Rosa Parks Downtown Station
1956 Gale Lemerand Drive
Gainesville Bus Stop
3509 SW Williston Rd

With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.