Cheap bus tickets from Gainesville to Panama City
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Bus from Gainesville to Panama City: Journey Information
There is one daily bus from Gainesville to Panama City. Traveling by bus from Gainesville to Panama City usually takes around 6 hours and 8 minutes, but the fastest Greyhound bus can make the trip in 6 hours and 5 minutes.
Distance | 203 mi (326 km) |
Shortest duration | 6h 5m |
Cheapest price | €32.92 |
Most frequent service | Greyhound |
Bus lines | 2 |

How much is a bus ticket from Gainesville to Panama City?
Bus tickets for a trip from Gainesville to Panama City cost €40.20 on average. Tickets cheaper than €40.20 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Gainesville to Panama City by travel date
Over the next four weeks, the average price of bus tickets from Gainesville to Panama City is expected to be between €38 and €54. The cheapest day to travel in the next month is May 5, 2025, when tickets are available for May 5, 2025. The cheapest bus tickets available in the next week start at just €39.
Monthly avg. prices
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 21 days in advance. This way, you can save up to €34.65 on your bus ticket compared to booking last-minute.
What bus companies travel from Gainesville to Panama City?
There are two bus lines that have daily service from Gainesville to Panama City that you can compare and book on Wanderu. However, each company only runs one bus per day.
Bus | Daily Trips | Avg. Time | Avg. Price |
---|---|---|---|
FlixBus US | 1 | 6h 20m | €73.88 |
Greyhound | 1 | 6h 8m | €48.34 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Gainesville to Panama City, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from Gainesville to Panama City every day, with the average journey taking around 6 hours and 8 minutes to complete. Bus tickets for Greyhound trips to Panama City usually start from €33.
Frequently asked questions about traveling by bus from Gainesville to Panama City
The bus takes an average of 6 hours and 8 minutes to cover the 203 miles from Gainesville to Panama City. However, the fastest bus only takes 6 hours and 5 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
There is usually only one bus per day from Gainesville to Panama City. It leaves the station in Gainesville at 8:00am each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Gainesville



Blessed with amazing natural landmarks and a vibrant cultural life, Gainesville offers a whole new Florida experience that is far from the decadence often associated with the state. If you wish to explore creative works made by local artists, head over to the Cade Museum for Creativity & Invention, which features great exhibitions that dive into the life of many inventors and entrepreneurs. Another great museum to visit is the Samuel P. Harn Museum of Art. For those who want to marvel at the city’s natural landmarks, go for a hiking trip along the trails of Alfred A. Ring Park, or the Barr Hammock Preserve.
Gainesville’s local favorite is the 4 Rivers Smokehouse, which offers delicious briskets. For some of the freshest local dishes, head over to Alpin Bistro.
The main bus station in Gainesville is the Greyhound Bus Terminal located on NE 23rd Ave, which welcomes buses from Miami, Fort Lauderdale, Houston and beyond. There is no rail service to Gainesville. However, the city is part of Amtrak’s network via the carrier’s Thruway bus service, which operates out of the same station. The main airport is the Gainesville Regional Airport, which lies in the northeast part of the city.
Station Information
Where does the bus leave from in Gainesville?
Main departure station: Gainesville Bus Stop
Gainesville’s bus terminal at 101 NE 23rd Ave is located a few miles north of downtown Gainesville, in a retail area including dollar stores and several takeout restaurants. Greyhound and Amtrak Thruway intercity buses operate trips from this station to cities like Orlando, Atlanta, and Miami. The station building has an information desk, restrooms, and vending machines for travelers’ convenience.
All bus stations in Gainesville:
Gainesville Bus Stop
Rosa Parks Downtown Station
Where does the bus arrive in Panama City?
Main arrival station: Panama City Bch Station
All buses from Gainesville arrive at one main station in Panama City.
All bus stations in Panama City:
Panama City Bch Station
Get around town with Moovit
Need a return trip from Panama City to Gainesville?
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- United States
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- Gainesville, FL to Panama City, FL