Cheap bus tickets from Tampa to Panama City
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Bus from Tampa to Panama City: Journey Information
There is one daily bus from Tampa to Panama City. Traveling by bus from Tampa to Panama City usually takes around 8 hours and 45 minutes, but the fastest Greyhound bus can make the trip in 8 hours and 30 minutes.
Distance | 246 mi (396 km) |
Shortest duration | 8h 30m |
Cheapest price | €35.13 |
Most frequent service | Greyhound |
Bus lines | 2 |

How much is a bus ticket from Tampa to Panama City?
Bus tickets for a trip from Tampa to Panama City cost €46.54 on average. Tickets cheaper than €46.54 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Tampa to Panama City by travel date
If you're planning to travel by bus from Tampa to Panama City in the next month, the average ticket price is expected to range from €43 to €64. The cheapest bus tickets available in the next few weeks are for trips departing on February 12, 2025.
If you’re looking to travel to Panama City this week, bus tickets are available starting at €43.
Prices as travel date approaches
To save money on bus tickets, buy them as early as possible. Bus carriers usually charge higher ticket prices the closer you book to the date of travel. Book your ticket at least 17 days in advance to save up to €34.44.
What bus companies travel from Tampa to Panama City?
There are two bus lines that have daily service from Tampa to Panama City that you can compare and book on Wanderu. However, each company only runs one bus per day.
Bus | Daily Trips | Avg. Time | Avg. Price |
---|---|---|---|
FlixBus US | 2 | 16h 12m | €63.60 |
Greyhound | 1 | 8h 30m | €50.16 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Tampa to Panama City, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from Tampa to Panama City every day, with the average journey taking around 8 hours and 30 minutes to complete. Bus tickets for Greyhound trips to Panama City usually start from €35.
Frequently asked questions about traveling by bus from Tampa to Panama City
The bus takes an average of 8 hours and 45 minutes to cover the 246 miles from Tampa to Panama City. However, the fastest bus only takes 8 hours and 30 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Travelers prefer riding the bus on Saturday to enjoy the weekend in Panama City. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
There is usually only one bus per day from Tampa to Panama City. It leaves the station in Tampa at 6:00am each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Tampa



Sitting at the heart of the Gulf Coast, Tampa offers a perfect blend of cultural attractions and relaxing indulgences. Infused with a colorful mix of Cuban and Spanish cultural elements, the city of Tampa houses some of the most impressive historic buildings in the state, including the Henry B. Plant Museum, which boasts a permanent exhibition of Victorian-era artifacts. Animal lovers can also rejoice, as the city’s many aquariums and zoos will certainly melt your heart. Head down to the Tampa Electric’s Manatee Viewing Center for some heart-melting cuteness. And for animal lovers with a penchant for streaming docu-series, the Big Cat Rescue (yes, THAT one!) will be a great choice.
Most of the finest restaurants in town are concentrated around the Riverwalk area, which offers unrivaled views of the waterfront. Oystercatchers is reputed as one of the best establishments in town, so you should not miss out on it. Tampa’s cuisine features a very clear Cuban influence, and the best spot to try out these unique fusion dishes is at Ybor City.
The principal train station in the city is the Tampa Union Station, which is also a historic building. It is currently served by Amtrak. At the station, travelers can also take an Amtrak Thruway motorcoach to get to Orlando, Lakeland, Bradenton, etc. The main airport is Tampa International Airport, which is located just six miles west of downtown Tampa.
Station Information
Where does the bus leave from in Tampa?
Main departure station: Tampa Bus Station
Located on Polk Street, the Greyhound Bus Terminal is Tampa’s main terminal for intercity bus service to cities such as Orlando, Miami, and Atlanta. Travelers on Greyhound will find ample parking in the surrounding area and a comfortable waiting room with restrooms and a small café inside. Conveniently located in the North Franklin St Historic District in downtown Tampa, the bus terminal is within a short walk of several dining options and connections to local public transit to travel within Tampa.
All bus stations in Tampa:
Tampa Bus Station
Tampa USF, FL
Where does the bus arrive in Panama City?
Main arrival station: Panama City Bch Station
All buses from Tampa arrive at one main station in Panama City.
All bus stations in Panama City:
Panama City Bch Station
Get around town with Moovit
Need a return trip from Panama City to Tampa?
Search Bus TicketsPlan your next adventure
More buses from Tampa
Continue by bus from Panama City
Check out these popular routes

Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
- Bus Tickets
- United States
- Florida
- Panama City
- Tampa to Panama City