Cheap bus tickets from Iowa City to St Louis
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Iowa City to St Louis Bus Schedule
Bus from Iowa City to St Louis: Journey Information
There are 2 intercity buses per day from Iowa City to St Louis. Traveling by bus from Iowa City to St Louis usually takes around 6 hours and 53 minutes, but the fastest Burlington Trailways bus can make the trip in 6 hours and 40 minutes.
| Distance | 221 mi (356 km) |
| Shortest duration | 6h 40m |
| Cheapest price | HUF 27,226.89 |
| Trips per day | 2 |
| Most frequent service | Burlington Trailways |
| Bus lines | 1 |

Price trends for buses from Iowa City to St Louis
Monthly avg. prices
What bus companies travel from Iowa City to St Louis?
There is one intercity bus company available to search and book on Wanderu that operates from Iowa City to St Louis. Burlington Trailways is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Burlington Trailways | 2 | 6h 53m | HUF 28,067.23 |
Book Burlington Trailways from Iowa City to St Louis from HUF 27,227. There are 2 trips per day offered by Burlington Trailways from Iowa City to St Louis and you can expect on average to pay for a Burlington Trailways ticket to St Louis. In Iowa City, Burlington Trailways departs to St Louis from Burlington Trailways Station - 170 E Court St . In St Louis, Burlington Trailways arrives at Saint Louis Lambert Fld and one other station.
An average trip on Burlington Trailways from Iowa City to St Louis takes 6 hours and 53 minutes , while the fastest available Burlington Trailways trip will get you to St Louis in 6 hours and 40 minutes .
Frequently asked questions about traveling by bus from Iowa City to St Louis
The bus takes an average of 6 hours and 53 minutes to cover the 221 miles from Iowa City to St Louis. However, the fastest bus only takes 6 hours and 40 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 9:00am and the last bus leaves at 9:00am. To see the times for all buses from Iowa City to St Louis, enter your specific travel dates in the search bar.
City Information
Iowa City

Image credit: Unsplash

Image credit: Unsplash

Image credit: Pixabay
The old capital city of Iowa, Iowa City, is a historic area with plenty of quaint old buildings and beautiful landmarks. The most notable attraction is the Old Capitol Building in the middle of the University of Iowa's campus. The building's first floor is a museum dedicated to the state's history so that you can brush up on your Hawkeye State knowledge (we'll get you started: the Iowa state rock is the geode!). For more history and culture, hit up Plum Grove, the home of the first Governor of Iowa, and the University of Iowa Art Museum.
Thanks to its lively cultural scene, Iowa City's food scene is vibrant and diverse. One of the must-try establishments in the city is Short's Burger and Shine, which features a wide variety of burgers made from locally sourced meat. In addition, the Hamburg Inn No. 2 is an award-winning restaurant, with visitors including many past presidents.
Bus service to Iowa City arrives right downtown for easy access to Iowa City's highlights. Although there is a small municipal airport in Iowa City, most commercial flights will depart from nearby Cedar Rapids Airport or even from Des Moines, about 100 miles away.
St Louis

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.
Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.
Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.
The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.
Station Information
Where does the bus leave from in Iowa City?
Main departure station: Burlington Trailways Station - 170 E Court St
The Burlington Trailways Station in Iowa City is part of the Court St Transportation Center near downtown. Buses usually board outside the multi-story parking garage on Court Street. The station includes a large indoor waiting area with seating, restrooms, and even a charging station for your devices. You can walk to three hotels, a sushi restaurant, a Mexican restaurant, a Starbucks, and a bar in the immediate area, so you definitely won't have to travel hungry or thirsty. Greyhound and Burlington Trailways buses depart from this station and connect Iowa City to Des Moines, Chicago, Omaha, and more cities throughout the Midwest.
All bus stations in Iowa City:
Burlington Trailways Station - 170 E Court St
Where does the bus arrive in St Louis?
Main arrival station: Saint Louis Lambert Fld
These are the two stations where buses may stop when they arrive in St Louis.
All bus stations in St Louis:
Saint Louis Lambert Fld
Gateway Station - 430 S 15th St
Get around town with Moovit
Need a return trip from St Louis to Iowa City?
Search Bus TicketsPlan your next adventure
More buses from Iowa City
- Bus from Ames to Des Moines
HUF 6,723+
- Ames to Minneapolis Bus
HUF 19,737+
- Cedar Rapids to Des Moines Bus
HUF 15,546+
- Cedar Rapids to Chicago Bus
HUF 25,546+
- Bus from Davenport to Des Moines
HUF 15,126+
- Davenport to Chicago Bus
HUF 12,689+
- Davenport to Indianapolis Bus
HUF 20,282+
- Davenport to Milwaukee Bus
HUF 13,524+
- Dubuque to Chicago
HUF 23,193+
- Bus from Grinnell to Cedar Rapids
HUF 12,941+
- Bus from Grinnell to Chicago
HUF 28,908+
- Iowa City to Davenport Bus
HUF 7,731+
- Bus from Iowa City to Des Moines
HUF 13,501+
- Iowa City to Waterloo Bus
HUF 11,261+
- Bus from Iowa City to Chicago
HUF 15,126+
- Bus from Iowa City to Omaha
HUF 24,538+
- Bus from Mt Pleasant to Cedar Rapids
HUF 9,916+
- Ottumwa to Des Moines Bus
HUF 13,445+
Continue by bus from St Louis
- Bus from St Louis to Orlando
HUF 53,240+
- Bus from St Louis to Atlanta
HUF 28,784+
- Bus from St Louis to Des Moines
HUF 39,328+
- Bus from St Louis to Carbondale
HUF 8,290+
- St Louis to Champaign
HUF 12,657+
- St Louis to Chicago
HUF 18,407+
- St Louis to Indianapolis Bus
HUF 14,622+
- St Louis to Paducah Bus
HUF 12,864+
- Bus from St Louis to Boston
HUF 55,385+
- Bus from St Louis to Minneapolis
HUF 35,770+
- St Louis to Columbia Bus
HUF 10,053+
- St Louis to Kansas City
HUF 14,796+
- St Louis to Raleigh
HUF 57,504+
- Bus from St Louis to Columbus
HUF 17,974+
- St Louis to Oklahoma City Bus
HUF 26,747+
- Bus from St Louis to Memphis
HUF 15,092+
- Bus from St Louis to Nashville
HUF 18,273+
- Bus from St Louis to Dallas
HUF 33,148+

Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
- Bus Tickets
- United States
- Missouri
- St Louis
- Iowa City to St Louis






