The busiest time of the week for travel from Champaign to Guadalajara by bus is at 6:00 PM on Saturday. When planning to travel around this time, tickets should be booked well in advance as they may sell out. Around 4:00 PM on Friday is when the fewest number of bus tickets are sold. If you’re looking for a little extra space, the bus departing at this time is the least likely to be crowded.