Cheap bus tickets from Omaha to La Crosse
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Omaha to La Crosse Bus Schedule
Bus from Omaha to La Crosse: Journey Information
There is one daily bus from Omaha to La Crosse. Traveling by bus from Omaha to La Crosse usually takes around 17 hours and 30 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 299 mi (482 km) |
| Shortest duration | 17h 30m |
| Cheapest price | £126.99 |
| Most frequent service | Jefferson Lines |
| Bus lines | 1 |

What bus companies travel from Omaha to La Crosse?
There is one intercity bus company available to search and book on Wanderu that operates from Omaha to La Crosse. Jefferson Lines is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Jefferson Lines | 1 | 17h 30m | £126.99 |
Book Jefferson Lines from Omaha to La Crosse from £127. Typically there is one Jefferson Lines schedule per day from Omaha to La Crosse and you can expect on average to pay for a Jefferson Lines ticket to La Crosse. In Omaha, Jefferson Lines departs to La Crosse from Burlington Trailways Terminal . In La Crosse, Jefferson Lines arrives at 314 Jay St .
An average trip on Jefferson Lines from Omaha to La Crosse takes 17 hours and 30 minutes .
Frequently asked questions about traveling by bus from Omaha to La Crosse
The bus takes an average of 17 hours and 30 minutes to cover the 299 miles from Omaha to La Crosse. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from Omaha to La Crosse. It leaves the station in Omaha at 9:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Omaha



Once known as the “Gateway to the West,” Omaha effortlessly blends its rich historical heritage with modern growth. To catch an air of the city’s old-town vibe, head towards the Old Market quarter. Featuring brick-paved streets along with horse-drawn carriages, the area is an idyllic time capsule that offers a glimpse into the past. Also situated within the quarter are the Joslyn Art Museum and the Omaha Children’s Museum. Animal lovers might want to check out Omaha’s Doorly Zoo or the Aquarium, which features cute Rockhopper penguins as well as a 70-foot shark tunnel.
Steakhouses dominate the city’s restaurant scene, but there has been a recent boom of modern eateries. If you wish to enjoy these modern foods, Kitchen Table will offer everything you need.
The busiest bus station in the city is the Burlington Trailways Terminal downtown. For trains, the main Amtrak station is located on S 9th St, not too far from the bus station. Omaha is served by Amtrak’s California Zephyr line. The city’s principal airport is the Eppley Airfield, located 3 miles northeast of downtown.
La Crosse
A busy college town blessed with lush and beautiful green zones, La Crosse is one of the best places to just chill out and unwind. The city's star attraction is the Grandad Bluff, which offers a panoramic view of the entire city and the Mississippi River. Hiking up the hill will certainly be a challenge, but the view from the top makes it all worthwhile. While staying in the city, don't miss out on the chance to go on a cruise aboard the La Crosse Queen, a replica paddle steamer, and unwind while enjoying the sunset. For some family fun, head over to the Children's Museum of La Crosse.
La Crosse does have a pretty reputable food scene, with a strong focus on beers and cheese curds. For an upscale dining experience with the best local dishes, The Waterfront Restaurant & Tavern is a local favorite that has a stellar reputation. Or head to the Dublin Square Irish Pub & Eatery for a combination of good foods and drinks.
La Crosse is easily accessible by bus or train, and regional flights operate out of the La Crosse Municipal Airport.
Station Information
Where does the bus leave from in Omaha?
Main departure station: Burlington Trailways Terminal
The Burlington Trailways Station on Jackson St, located in east Omaha, provides bus services for several bus carriers: Greyhound, Jefferson Lines, Express Arrow, and Burlington Trailways. The station features an indoor waiting area, as well as vending machines and restrooms. The Burlington Trailways station is only a short walk from several cafes and restaurants if you feel like grabbing something more substantial to get you through your bus journey.
All bus stations in Omaha:
Burlington Trailways Terminal
Where does the bus arrive in La Crosse?
Main arrival station: 314 Jay St
Buses to La Crosse stop at Jay Street in front of the Grand River Station. The aptly-named grand building features arching ceilings, marble decoration, and amenities like seating and vending machines inside. The station is conveniently located in downtown La Crosse with easy access to surrounding hotels, restaurants, and a rental car agency across the street. Bus lines, including Greyhound and Jefferson Lines, connect La Crosse to Minneapolis, Milwaukee, Chicago, and beyond.
All bus stations in La Crosse:
314 Jay St
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