Cheap bus tickets from Harrisburg to Winston-Salem
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Harrisburg to Winston-Salem Bus Schedule
Bus from Harrisburg to Winston-Salem: Journey Information
There is one daily bus from Harrisburg to Winston-Salem. Traveling by bus from Harrisburg to Winston-Salem usually takes around 21 hours and 15 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 341 mi (549 km) |
| Shortest duration | 21h 15m |
| Cheapest price | HUF 61,818 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

What bus companies travel from Harrisburg to Winston-Salem?
There is one intercity bus company available to search and book on Wanderu that operates from Harrisburg to Winston-Salem. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 21h 15m | HUF 61,818 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Harrisburg to Winston-Salem, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Harrisburg to Winston-Salem
The bus takes an average of 21 hours and 15 minutes to cover the 341 miles from Harrisburg to Winston-Salem. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
There is usually only one bus per day from Harrisburg to Winston-Salem. It leaves the station in Harrisburg at 5:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
There is usually only one bus per day from Harrisburg to Winston-Salem. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.
Need more travel options? Consider taking the train from Harrisburg to Winston-Salem; ticket prices start at HUF 75,465.
City Information
Harrisburg



As the capital city of Pennsylvania, Harrisburg offers numerous historic buildings with impressive architecture that will leave you in awe. Among the most impressive ones is the state’s Capitol Complex itself. With a dome that reminisces St. Peter’s Basilica in Rome, the building features as many as 475 rooms filled with exquisite artworks and statues. History fans should also consider visiting the State Museum of Pennsylvania, which follows the history of the state from the beginning of time to this day. Another must-see destination is the National Civil War Museum, which is one of the largest museums dedicated to the Civil War. If too many history lessons stress you out, a cruise along the Susquehanna River on the Pride of the Susquehanna Riverboat will definitely help you unwind.
Harrisburg’s grilled dishes are some of the most famous staples in the city, and among the best establishments is Progress Grill, which has been serving customers since the late 1940s. For some really creative pizzas, The Pizza Grille will be a good choice.
The Harrisburg Transportation Center is the central hub for intercity travel. At the lower level, you can catch a bus by Greyhound, Jefferson Lines or Fullington Trailways to other Pennsylvanian cities such as Allentown and Philadelphia. Travelers can also take Amtrak trains to popular destinations like New York and Philadelphia on a daily basis. The city’s principal airport is Harrisburg International Airport, which is located in Middletown, southeast of the city.
Winston-Salem

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
Ranked as one of the top places to live in the United States, Winston-Salem resulted from the merging of two separate towns in 1913.
The city's oldest and most visually arresting areas are found in what was once simply Salem, a town with a history going back to 1753. You can admire many of the original Moravian-style buildings at Old Salem Museums & Gardens and in the historic districts of West End and Ardmore.
Downtown also has some notable structures, including 100 North Main Street – the tallest office building in the region.
Meanwhile, the main strip when it comes to nightlife is Fourth Street, where bars and restaurants see a steady stream of patrons until long after dark. The presence of no less than six higher education institutions in the city ensures the scene remains fresh and vibrant.
Winston-Salem can be reached from over 175 other U.S. cities. Daily buses depart and arrive from the city's three bus terminals throughout the day, with destinations that include Raleigh, Richmond, and New York City. In addition, Amtrak operates passenger train services via the station at High Point. Its three lines span the region from New York to New Orleans.
Station Information
Where does the bus leave from in Harrisburg?
Main departure station: Harrisburg Transportation Center
Most buses depart from the main station in Harrisburg.
All bus stations in Harrisburg:
Harrisburg Transportation Center
Where does the bus arrive in Winston-Salem?

Image credit: Warren LeMay
Link to image attributionMain arrival station: Transp Ctr - 100 W 5th St
The Winston-Salem Transportation Center is on the corner of 5th Street & Trade Street, smack in the middle of the city. It's also commonly called the Greyhound bus station, since the carrier provides a lot of service across North Carolina and its neighboring states. There are plenty of great restaurants in the area, like Butcher & Bull Steakhouse, Downtown Thai & Pho, and Downtown Deli and Cafe, if you want to fill up before your trip. Or, if you want to stretch your legs, Bailey's Park is only a few blocks away and frequently has live music and events.
All bus stations in Winston-Salem:
Transp Ctr - 100 W 5th St
Get around town with Moovit
Need a return trip from Winston-Salem to Harrisburg?
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- Bus Tickets
- United States
- North Carolina
- Winston-Salem
- Harrisburg to Winston-Salem






