Cheap bus tickets from Knoxville to Chicago
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Knoxville to Chicago Bus Schedule
Bus from Knoxville to Chicago: Journey Information
There are 5 intercity buses per day from Knoxville to Chicago. Traveling by bus from Knoxville to Chicago usually takes around 16 hours and 56 minutes, but the fastest Greyhound bus can make the trip in 14 hours and 50 minutes.
| Distance | 455 mi (732 km) |
| Shortest duration | 14h 50m |
| Cheapest price | HUF 30,600 |
| Most frequent service | Greyhound |
| Bus lines | 1 |

How much is a bus ticket from Knoxville to Chicago?
Bus tickets for a trip from Knoxville to Chicago cost HUF 34,273 on average. Bus tickets on this route can be a bit expensive due to the length of the trip. But even with a higher price tag, taking the bus is often more affordable than flying to Chicago. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Monthly avg. prices
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 27 days in advance. This way, you can save up to HUF 39,238 on your bus ticket compared to booking last-minute.
What bus companies travel from Knoxville to Chicago?
There is one intercity bus company available to search and book on Wanderu that operates from Knoxville to Chicago. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 5 | 16h 56m | HUF 53,933 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 5 bus trips from Knoxville to Chicago every day, with the average journey taking around 16 hours and 56 minutes to complete. Bus tickets for Greyhound trips to Chicago usually start from HUF 30,600.
Frequently asked questions about traveling by bus from Knoxville to Chicago
The bus takes an average of 16 hours and 56 minutes to cover the 455 miles from Knoxville to Chicago. However, the fastest bus only takes 14 hours and 50 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
With many people traveling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to Chicago, book your ticket for the last day of the week.
The first bus leaves at 6:00pm and the last bus leaves at 10:00pm. To see the times for all buses from Knoxville to Chicago, enter your specific travel dates in the search bar.
City Information
Chicago



Known for its innovative architecture, cultural contributions to jazz and house music, and of course that irresistible deep-dish pizza, the many sights and experiences in Chicago make it one of the best urban vacation destinations for millennials and a top destination in Illinois.
You can't beat the views of the city and Lake Michigan from the SkyDeck in the Willis Tower; at over 1,300 feet, this is the highest observation deck in the U.S. Snap that classic selfie with the Bean in Millennium Park, then wander the many museums in nearby Grant Park. Navy Pier is a popular tourist hotspot for its parks, restaurants, and attractions right on Lake Michigan, and baseball fans will find paradise in Wrigleyville, home to the Chicago Cubs' Wrigley Field and sports bars galore.
Chicago's enormous parks offer plentiful opportunities for outdoor activities in gorgeous urban settings. Many companies offer kayak rentals or boat tours on the Chicago River, with special tours running on Saint Patrick's Day, when the entire river is dyed green. When you’re ready to buy some souvenirs from your epic trip, hit the big brand stores on the Magnificent Mile, or shop local in neighborhoods like Andersonville and Wicker Park. And don't miss the chance to laugh until you cry at The Second City comedy theater, famous for launching the careers of comedians like Tina Fey and Stephen Colbert.
Chicago is one of the biggest transportation hubs in the Midwest, and provides easy access to nearby destinations ideal for day trips, as well as international travel from two airports. Thanks to plenty of bus and train stations throughout the city, getting to the Windy City is a breeze.
Station Information
Where does the bus leave from in Knoxville?
Main departure station: Knoxville Bus Station
Most buses depart from the main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
Where does the bus arrive in Chicago?

Image credit: Jeramey Jannene
Link to image attributionMain arrival station: Bus Station - 630 W Harrison St
Buses arrive in Chicago at 3 stations, depending on which bus line you are traveling with.
All bus stations in Chicago:
Bus Station - 630 W Harrison St
Dan Ryan Bus Station
Chicago Train Station Bus Stop
Get around town with Moovit
Need a return trip from Chicago to Knoxville?
Search Bus TicketsPlan your next adventure
More buses from Knoxville
- Chattanooga to Atlanta Bus
HUF 8,721+
- Bus from Chattanooga to Knoxville
HUF 8,540+
- Chattanooga to Nashville
HUF 8,208+
- Clarksville to Nashville
HUF 4,503+
- Jackson to Nashville Bus
HUF 12,388+
- Johnson City to New York
HUF 36,731+
- Knoxville to Atlanta Bus
HUF 16,719+
- Knoxville to Charlotte Bus
HUF 39,477+
- Bus from Knoxville to New York
HUF 36,731+
- Knoxville to Chattanooga Bus
HUF 8,253+
- Bus from Knoxville to Memphis
HUF 38,757+
- Knoxville to Nashville Bus
HUF 14,049+
- Bus from Memphis to Atlanta
HUF 22,395+
- Memphis to Nashville
HUF 18,021+
- Bus from Murfreesboro to Atlanta
HUF 14,488+
- Bus from Murfreesboro to Nashville
HUF 3,982+
- Bus from Nashville to Atlanta
HUF 14,384+
- Nashville to Memphis Bus
HUF 16,244+
Continue by bus from Chicago
- Bus from Chicago to Celaya
HUF 90,297+
- Chicago to Birmingham Bus
HUF 47,741+
- Bus from Chicago to Goshen
HUF 10,713+
- Chicago to Indianapolis
HUF 14,774+
- Bus from Chicago to New Orleans
HUF 54,201+
- Bus from Chicago to Detroit
HUF 15,740+
- Bus from Chicago to Flint
HUF 16,461+
- Bus from Chicago to Traverse City
HUF 16,376+
- Chicago to Minneapolis Bus
HUF 24,732+
- Bus from Chicago to St Louis
HUF 19,479+
- Bus from Chicago to Omaha
HUF 27,020+
- Bus from Chicago to Akron
HUF 20,397+
- Chicago to Oklahoma City Bus
HUF 52,188+
- Chicago to Richmond
HUF 50,471+
- Chicago to Milwaukee
HUF 9,719+
- Bus from Chicago to Wausau
HUF 10,178+
- Chicago to Charleston Bus
HUF 24,997+
Check out these popular routes
- Bus from Calgary to Edmonton
HUF 7,387+
- Bus from Vancouver to Seattle
HUF 12,061+
- Toronto to Ottawa Bus
HUF 8,370+
- Montreal to New York Bus
HUF 28,908+
- Bus from Atlanta to New York
HUF 41,713+
- Boston to New York
HUF 7,790+
- Brooklyn to Washington D.C. Bus
HUF 11,842+
- Ithaca to New York Bus
HUF 15,715+
- Bus from New York to Montreal
HUF 28,755+
- Bus from New York to Washington D.C.
HUF 7,663+
- Bus from New York to Boston
HUF 8,232+
- New York to Ithaca Bus
HUF 14,158+
- Bus from New York to Philadelphia
HUF 5,261+
- Philadelphia to Brooklyn Bus
HUF 4,591+
- Bus from Philadelphia to New York
HUF 4,805+
- Dallas to Houston Bus
HUF 12,657+
- Houston to Dallas Bus
HUF 12,066+
- Madison to Chicago Bus
HUF 11,662+

Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
- Bus Tickets
- United States
- Illinois
- Chicago
- Knoxville to Chicago






