|Shortest Duration||11h 55m|
|Trips per day||4|
Book Greyhound from Knoxville to St Louis from $103.00. There are 4 trips per day offered by Greyhound from Knoxville to St Louis and you can expect on average to pay $127.79 for a Greyhound ticket to St Louis. In Knoxville, Greyhound departs to St Louis from Bus Terminal - 100 E Magnolia Ave, In St Louis, Greyhound arrives at Gateway Station - 430 S 15th St and one other station.
An average trip on Greyhound from Knoxville to St Louis takes 13 hours and 22 minutes, while the fastest available Greyhound trip will get you to St Louis in 11 hours and 55 minutes,
On weekends, Greyhound offers 4 trips per day. A one way ticket costs $153.81 for a weekend trip to St Louis.