|Shortest Duration||9h 0m|
|Trips per day||2|
Book Jefferson Lines from La Crosse to Des Moines from $79.00. There are 2 trips per day offered by Jefferson Lines from La Crosse to Des Moines and you can expect on average to pay $82.60 for a Jefferson Lines ticket to Des Moines. In La Crosse, Jefferson Lines departs to Des Moines from 314 Jay St and one other station. In Des Moines, Jefferson Lines arrives at Bus Station - 1501 2nd St,
An average trip on Jefferson Lines from La Crosse to Des Moines takes 9 hours and 23 minutes, while the fastest available Jefferson Lines trip will get you to Des Moines in 9 hours and 0 minutes,
On weekends, Jefferson Lines offers 2 trips per day. A one way ticket costs $87.00 for a weekend trip to Des Moines.