Search La Crosse to Des Moines  bus tickets



La Crosse to Des Moines bus - cost & duration

Cheapest price$79.00
Shortest Duration9h 0m
Trips per day2
bus carriers1
Lowest prices
We partner with 100s of bus, train & ferry operators to find you the best fares.
No wanderu fees
We simply offer you the lowest prices directly from the carrier.
Best travel options
We offer the safest & most reliable options on millions of routes.

How to book cheap La Crosse to Des Moines bus tickets?

The best way to find cheap deals on bus tickets from La Crosse to Des Moines is by booking earlier as most bus companies increase the price as the departure date approaches. Based on the last 30 days, the cheapest average bus fares from La Crosse to Des Moines were $82.47. By booking 7 days out, tickets are on average $0.00 cheaper than those that are booked last minute.

What is the busiest time to travel by bus from La Crosse to Des Moines?

The busiest time of the week for travel from La Crosse to Des Moines by bus is usually around 1:00 PM on Sunday. When planning to travel around this time, tickets should be booked well in advance as they may sell out and you may find buses more full than usual. Around 2:00 PM on Sunday tends to be when the fewest number of bus tickets are sold. If you’re looking for a little extra space, buses departing at this time are the least likely to be crowded.

Jefferson Lines from La Crosse to Des Moines has the most daily schedules

On average there are 2 scheduled bus trips per day. Jefferson Lines has the most regularly scheduled departures from La Crosse to Des Moines, with an average of 2 trips per day and 31 monthly trips. One bus carrier currently travels from La Crosse to Des Moines. Of the 2 trips there all of the schedules require a connection as there are no direct trips. A connection will generally require disembarking from the bus and boarding another bus to complete your trip.

1 carriers offer La Crosse to Des Moines bus trips

Jefferson Lines

Book Jefferson Lines from La Crosse to Des Moines from $79.00. There are 2 trips per day offered by Jefferson Lines from La Crosse to Des Moines and you can expect on average to pay $82.60 for a Jefferson Lines ticket to Des Moines. In La Crosse, Jefferson Lines departs to Des Moines from 314 Jay St and one other station. In Des Moines, Jefferson Lines arrives at Bus Station - 1501 2nd St,

An average trip on Jefferson Lines from La Crosse to Des Moines takes 9 hours and 23 minutes, while the fastest available Jefferson Lines trip will get you to Des Moines in 9 hours and 0 minutes,

On weekends, Jefferson Lines offers 2 trips per day. A one way ticket costs $87.00 for a weekend trip to Des Moines.

Power outlet
Air conditioning
Avg. Time
9h 23m
Avg. Price

Plan your next adventure:

Depending on the bus line you travel with, your options include 2 stations that have bus departures from La Crosse. Most bus trips to Des Moines will depart from 314 Jay St, University of Wisconsin.
  • 314 Jay St
  • University of Wisconsin
Bus trips arrive in Des Moines at 1 stations, depending on which bus line you are traveling with. Bus Station - 1501 2nd St are the main bus stations in Des Moines for trips arriving from La Crosse.
  • Bus Station - 1501 2nd St