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Indianapolis to Winston-Salem bus

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Indianapolis - Winston-Salem Bus Schedule

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Journey Information

There are 5 intercity buses per day from Indianapolis to Winston-Salem. Traveling by bus from Indianapolis to Winston-Salem usually takes around 19 hours and 53 minutes, but the fastest Greyhound bus can make the trip in 14 hours and 15 minutes.

Distance410 mi (660 km)
Shortest duration14h 15m
Cheapest price$57.48
Most frequent serviceGreyhound
Bus lines2

What bus companies travel from Indianapolis to Winston-Salem?

There are two bus lines that have daily service from Indianapolis to Winston-Salem that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 4 scheduled trips per day.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US219h 4m$150.54
Greyhound419h 55m$90.12
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Indianapolis to Winston-Salem, and the average ticket for this route costs only .

  • Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 4 bus trips from Indianapolis to Winston-Salem every day, with the average journey taking around 19 hours and 55 minutes to complete. Bus tickets for Greyhound trips to Winston-Salem usually start from $54.

Frequently Asked Questions

The bus takes an average of 19 hours and 53 minutes to cover the 410 miles from Indianapolis to Winston-Salem. However, the fastest bus only takes 14 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Tuesday is usually the day of the week when buses are busiest. If you are planning to travel on a Tuesday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Saturday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Saturday ticket is the way to go.

The first bus leaves at 6:00am and the last bus leaves at 8:00pm. To see the times for all buses from Indianapolis to Winston-Salem, enter your specific travel dates in the search bar.

There are 5 scheduled buses that travel from Indianapolis to Winston-Salem every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.

City Information

Indianapolis

Indianapolis, or often referred to as just Indy, is the capital and largest city in the state of Indiana. While the city attracts thousands of visitors from the area every month, it is during Memorial Day weekend that Indianapolis becomes the place to be for over 300,000 race car fans from all over the globe. The reason for that is the Indianapolis 500, an annual automobile race and the world’s largest single day sporting event, taking place at the iconic Indianapolis Motor Speedway.

If you’re not in Indianapolis for Memorial Day weekend, you can learn about the race and see a rare collection of 500 Indy race vehicles and memorabilia at the Indianapolis Motor Speedway Museum. And while you’re on a history streak, stop by at one of the many war memorials found throughout the city, like the Soldiers and Sailors monument, the World War II memorial, and the Indiana War Memorial where you must check out the Shrine Room for a stunning one-of-a-kind experience.

Over the past few years, Indianapolis has also been cultivating a vibrant restaurant scene, offering classic American dishes made with ingredients from local farmers, and a growing selection of international cuisine. If you’re a beer fan, you will be happy to know that Indianapolis has some of the highest quality breweries in the U.S.

Located in the heart of America’s Midwest, Indianapolis offers easy connections by bus and train to other Midwestern hubs like Chicago, Louisville, and Cincinnati, while the conveniently located airport connects Indy with the rest of the world.

Winston-Salem

Winston-Salem, NC - WSA-0

Image credit: Unsplash

Winston-Salem, NC - WSA-1

Image credit: Unsplash

Winston-Salem, NC - WSA-2

Image credit: Unsplash

Ranked as one of the top places to live in the United States, Winston-Salem resulted from the merging of two separate towns in 1913.

The city's oldest and most visually arresting areas are found in what was once simply Salem, a town with a history going back to 1753. You can admire many of the original Moravian-style buildings at Old Salem Museums & Gardens and in the historic districts of West End and Ardmore.

Downtown also has some notable structures, including 100 North Main Street – the tallest office building in the region.

Meanwhile, the main strip when it comes to nightlife is Fourth Street, where bars and restaurants see a steady stream of patrons until long after dark. The presence of no less than six higher education institutions in the city ensures the scene remains fresh and vibrant.

Winston-Salem can be reached from over 175 other U.S. cities. Daily buses depart and arrive from the city's three bus terminals throughout the day, with destinations that include Raleigh, Richmond, and New York City. In addition, Amtrak operates passenger train services via the station at High Point. Its three lines span the region from New York to New Orleans.

Station Information

Where does the bus leave from in Indianapolis?

Indianapolis, IN - Indianapolis Union Station (350 S Illinois St) - INDAMT-0

Image credit: Panoramio upload bot

Link to image attribution

Main departure station: 350 S Illinois St

Union Station at 350 S Illinois St in Indianapolis is a major train and bus station which serves the Amtrak Cardinal, and bus carriers including Greyhound, Jefferson Lines, Miller Transportation, and Burlington Trailways. The modern station is located directly south of the historic 1888 Union Station, which now houses a hotel, several restaurants, and a wedding venue. Union Station is in the Wholesale District of downtown Indianapolis, within walking distance to eateries and hotels. There is even an underground, climate-controlled walkway from the station to the nearby Indiana Convention Center and Lucas Oil Stadium, home to the Indianapolis Colts.

All bus stations in Indianapolis:

  • 350 S Illinois St

  • E Washington St

Where does the bus arrive in Winston-Salem?

Transp Ctr - 100 W 5th St -{"city":"Winston-Salem","country":"US","postal":"27101","state":"NC","street1":"100 West 5th Street  Corner of 5th Street & Trade Street"} - WSAWNS-0

Image credit: Warren LeMay

Link to image attribution

Main arrival station: Transp Ctr - 100 W 5th St

The Winston-Salem Transportation Center is on the corner of 5th Street & Trade Street, smack in the middle of the city. It's also commonly called the Greyhound bus station, since the carrier provides a lot of service across North Carolina and its neighboring states. There are plenty of great restaurants in the area, like Butcher & Bull Steakhouse, Downtown Thai & Pho, and Downtown Deli and Cafe, if you want to fill up before your trip. Or, if you want to stretch your legs, Bailey's Park is only a few blocks away and frequently has live music and events.

All bus stations in Winston-Salem:

  • Transp Ctr - 100 W 5th St

  • 100 W 5th St

Get around town with Moovit

Find the best way to get to and from any station in Winston-Salem by public transit, courtesy of Moovit. Search now

Need a return trip from Winston-Salem to Indianapolis?

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