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St Louis to Santa Ana bus

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St Louis - Santa Ana Bus Schedule

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Journey Information

There is one daily bus from St Louis to Santa Ana. Traveling by bus from St Louis to Santa Ana usually takes around 53 hours and 40 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.

Distance1573 mi (2532 km)
Shortest duration53h 40m
Cheapest price$343.01
Most frequent serviceFlixBus US
Bus lines1

What bus companies travel from St Louis to Santa Ana?

There is one intercity bus company available to search and book on Wanderu that operates from St Louis to Santa Ana. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US12d 5h 40m$343.01
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from St Louis to Santa Ana, and the average ticket for this route costs only .

Frequently Asked Questions

The bus takes an average of 53 hours and 40 minutes to cover the 1573 miles from St Louis to Santa Ana. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

The busiest and least busy days to travel on this route tend to change frequently from week to week. Weather, holidays, local events, and other factors can affect how crowded the bus is on any given day.

There is usually only one bus per day from St Louis to Santa Ana. It leaves the station in St Louis at 7:00am each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.

There is usually only one bus per day from St Louis to Santa Ana. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.

Need more travel options? Consider taking the train from St Louis to Santa Ana; ticket prices start at $199.00.

City Information

St Louis

St. Louis, MO - STL-0

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St. Louis, MO - STL-1

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St. Louis, MO - STL-2

Image credit: Unsplash

St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.

Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.

Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.

The main bus and train station in St. Louis, Gateway Station, is located right in the center of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.

Santa Ana

Santa Ana, CA, US - SNA-0

Image credit: Unsplash

Santa Ana is a sunny city in Orange County located between Anaheim and Irvine in the greater Los Angeles area. Downtown Santa Ana bustles with independent breweries, diverse restaurants, unique retail shops, weekly pop-up markets, and art centers. This lively downtown area, in addition to Santa Ana's live-work housing and creative working spaces, make it attractive to young professionals.

One of the most popular spots for visitors is the Santa Ana Zoo, where little ones can enjoy a carousel and mini-train ride along with the animal exhibits. Architecture enthusiasts will love seeing the Bowers Museum, built in a Mission Revival style, and the Heritage Museum, which has restored homes from the 1890s.

The Orange County Transportation Authority and several shuttle services provide transit within Santa Ana. Santa Ana is easily accessible from over 20 other cities by Amtrak Thruway bus or on the Amtrak Pacific Surfliner train. The primary airport for Orange County, John Wayne Airport, is located in Santa Ana and also makes it easy to travel to this vibrant SoCal spot.

Station Information

Where does the bus leave from in St Louis?

Main departure station: St Louis Lambert Field Bus Stop

Most buses depart from the main station in St Louis.

All bus stations in St Louis:

  • St Louis Lambert Field Bus Stop

Where does the bus arrive in Santa Ana?

Main arrival station: Reg Transp Ctr - 1000 E Santa Ana Blvd

All buses from St Louis arrive at one main station in Santa Ana.

All bus stations in Santa Ana:

  • Reg Transp Ctr - 1000 E Santa Ana Blvd

Get around town with Moovit

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Need a return trip from Santa Ana to St Louis?

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