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Journey Information
There are 2 intercity buses per day from Buffalo to La Crosse. Traveling by bus from Buffalo to La Crosse usually takes around 28 hours and 55 minutes, but the fastest Greyhound bus can make the trip in 28 hours and 50 minutes.
| Distance | 624 mi (1004 km) |
| Shortest duration | 28h 50m |
| Cheapest price | $120.00 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
What bus companies travel from Buffalo to La Crosse?
There is one intercity bus company available to search and book on Wanderu that operates from Buffalo to La Crosse. Greyhound is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 2 | 1d 4h 55m | $132.50 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Buffalo to La Crosse every day, with the average journey taking around 28 hours and 55 minutes to complete. Bus tickets for Greyhound trips to La Crosse usually start from $120.
Frequently Asked Questions
The bus takes an average of 28 hours and 55 minutes to cover the 624 miles from Buffalo to La Crosse. However, the fastest bus only takes 28 hours and 50 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 9:00am and the last bus leaves at 9:00am. To see the times for all buses from Buffalo to La Crosse, enter your specific travel dates in the search bar.
There are usually only 2 buses per day from Buffalo to La Crosse. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.
Need more travel options? Consider taking the train from Buffalo to La Crosse; ticket prices start at $140.00.
City Information
Buffalo
Buffalo is a great budget destination that will not burn through your pocket. Located just a few hours’ drive away from Niagara Falls, the city serves as a transportation hub for tourists who want to marvel at the sights of the famous landmark. Visitors can either enjoy the tour from a boat, or walk around the section behind the falls themselves. If you opt for a more idyllic and peaceful destination instead, Forest Lawn is a good choice. A beautiful cemetery that is far from the hustle and bustle of the big city, the destination is a perfect spot for a picnic. As the day winds down to an end, don’t hesitate to attend a performance at Shea’s Performing Arts Center, which features lavish interiors as well as amazing Broadway shows.
Buffalo’s chicken wings are the city’s trademark dish, and tourists who wish to grab a bite could do so at Duff’s Famous Wings or Anchor Bar. For a wider selection, The Left Bank is an even better option.
The principal bus station in Buffalo is the Metropolitan Transportation Center downtown. Travelers can catch buses by Greyhound, New York Trailways, Fullington Trailways and Barons Bus Lines from this station. The main Amtrak train station in Buffalo is located on Exchange St not too far from the bus station. Buffalo is served by Amtrak’s Empire Service and Maple Leaf lines. The city’s principal airport is the Buffalo Niagara International Airport, which is located in the suburb area of Cheektowaga. The city is also served by the nearby Niagara Falls International Airport.
La Crosse
A busy college town blessed with lush and beautiful green zones, La Crosse is one of the best places to just chill out and unwind. The city's star attraction is the Grandad Bluff, which offers a panoramic view of the entire city and the Mississippi River. Hiking up the hill will certainly be a challenge, but the view from the top makes it all worthwhile. While staying in the city, don't miss out on the chance to go on a cruise aboard the La Crosse Queen, a replica paddle steamer, and unwind while enjoying the sunset. For some family fun, head over to the Children's Museum of La Crosse.
La Crosse does have a pretty reputable food scene, with a strong focus on beers and cheese curds. For an upscale dining experience with the best local dishes, The Waterfront Restaurant & Tavern is a local favorite that has a stellar reputation. Or head to the Dublin Square Irish Pub & Eatery for a combination of good foods and drinks.
La Crosse is easily accessible by bus or train, and regional flights operate out of the La Crosse Municipal Airport.
Station Information
Where does the bus leave from in Buffalo?
Image credit: Can Pac Swire
Link to image attributionMain departure station: Downtown Terminal - 181 Ellicott St
The Downtown Terminal in Buffalo is the center of bus transportation in the city. The terminal currently serves many intercity bus lines such as Greyhound, FlixBus, Fullington Trailways, Barons Bus Lines, and New York Trailways. The station offers vending machines and even a Tim Horton’s for a taste of Canada’s favorite coffee and donuts. Situated in the heart of downtown Buffalo, travelers can easily access restaurants, hotels, or the Amtrak station on Exchange Street to continue their travels.
All bus stations in Buffalo:
Downtown Terminal - 181 Ellicott St
Where does the bus arrive in La Crosse?
Main arrival station: 314 Jay St
Buses to La Crosse stop at Jay Street in front of the Grand River Station. The aptly-named grand building features arching ceilings, marble decoration, and amenities like seating and vending machines inside. The station is conveniently located in downtown La Crosse with easy access to surrounding hotels, restaurants, and a rental car agency across the street. Bus lines, including Greyhound and Jefferson Lines, connect La Crosse to Minneapolis, Milwaukee, Chicago, and beyond.
All bus stations in La Crosse:
314 Jay St
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