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Florence to Syracuse bus

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Florence - Syracuse Bus Schedule

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Journey Information

There is one daily bus from Florence to Syracuse. Traveling by bus from Florence to Syracuse usually takes around 19 hours and 50 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.

Distance642 mi (1033 km)
Shortest duration19h 50m
Cheapest price$94.97
Most frequent serviceFlixBus US
Bus lines1

What bus companies travel from Florence to Syracuse?

There is one intercity bus company available to search and book on Wanderu that operates from Florence to Syracuse. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.

BusDaily TripsAvg. TimeAvg. Price
FlixBus US119h 50m$143.65
  • FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Florence to Syracuse, and the average ticket for this route costs only .

Frequently Asked Questions

The bus takes an average of 19 hours and 50 minutes to cover the 642 miles from Florence to Syracuse. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.

Because many passengers travel from Florence to Syracuse at the beginning of the work week, Monday is usually the busiest day for buses. If you are planning to travel on a Monday, you should make sure to book tickets well in advance as they may sell out.

On the other hand, Saturday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Saturday ticket is the way to go.

There is usually only one bus per day from Florence to Syracuse. It leaves the station in Florence at 11:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.

There is usually only one bus per day from Florence to Syracuse. However, it is not a direct bus, so you will have to get off your original vehicle to change buses during the trip.

Need more travel options? Consider taking the train from Florence, SC to Syracuse, NY; ticket prices start at $187.00.

City Information

Florence

Florence is a hidden gem in the northeast of South Carolina. Though best known for its history as a significant railway hub, Florence is a modern city with activities and sights to fill a weekend getaway or a longer vacation.

Every November, Florence goes nuts during the SC Pecan Music and Food Festival, an event hosted downtown to celebrate the beloved pecan. If you're in town during the festival, check out the car show, live music, half marathon, and other associated events to get to know Florence locals and culture.

Florence is a year-round destination for outdoor recreation. Golf is a favorite among Florence residents, so upgrade from mini-golf and try the real thing. Traces Golf Club welcomes golfers of all skill levels, don't worry. Don't leave Florence without spending a day at Lynches River County Park, the starting point of the 66-mile South Carolina Revolutionary Rivers Trail. You can kayak or canoe throughout the county, following the swampy path that allowed American patriots to evade British troops in the American Revolution.

Florence Regional Airport operates limited flights to connect to Charlotte, but most paths to Florence involve some kind of ground travel. Amtrak's Palmetto and Silver Service trains stop in Florence, with connections to New York and Washington to the north and Orlando and Miami to the south. Greyhound and Southeastern Stages offer intercity bus service to Florence that connects the city to other destinations throughout the South.

Syracuse

Syracuse, NY

Image credit: David Wilson

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Syracuse might not be the top destination for tourists in New York, but it does have plenty of quirky and fun destinations for all age groups. Upon your first arrival to the city, don’t miss out on the chance to take a stroll around the historic Armory Square, considered to be the top destination by locals. The square also features plenty of restaurants and nightclubs if you are looking for the quarter with the best nightlife in town. If you want to mingle with a good crowd for some fun, the Carrier Dome, which is located within the campus of Syracuse University, will offer the adrenaline rush you need. For those seeking a more culturally-inclined activity, head towards the Everson Museum of Art and marvel at the most significant collection of American ceramics in the country.

Syracuse features a vibrant and diverse food scene. If you enjoy brunch, Modern Malt, a local favorite, is the place to be. And for some amazing authentic Cuban dishes, head to Esquina Habanera.

The busiest bus and train station in the city is the William F. Walsh Regional Transportation Center. From there you can catch an Amtrak train or a bus run by Greyhound, New York Trailways, OurBus or Jefferson Lines to various cities, including New York, Boston, and Albany. Syracuse is served by Amtrak’s Empire Service, Lake Shore Limited and Maple Leaf lines. The Syracuse Hancock International Airport is the principal airport in the city, and it is located five miles northwest of downtown.

Station Information

Where does the bus leave from in Florence?

Main departure station: 2301 W Lucas St (TA Gas Station)

Most buses depart from the main station in Florence.

All bus stations in Florence:

  • 2301 W Lucas St (TA Gas Station)

Where does the bus arrive in Syracuse?

Main arrival station: 1 Walsh Circle Ste 30

All buses from Florence arrive at one main station in Syracuse.

All bus stations in Syracuse:

  • 1 Walsh Circle Ste 30

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