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Journey Information
There are 2 intercity buses per day from Greenville to La Crosse. Traveling by bus from Greenville to La Crosse usually takes around 38 hours and 50 minutes, but the fastest Greyhound bus can make the trip in 38 hours and 45 minutes.
| Distance | 778 mi (1251 km) |
| Shortest duration | 38h 45m |
| Cheapest price | $159.00 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
What bus companies travel from Greenville to La Crosse?
There is one intercity bus company available to search and book on Wanderu that operates from Greenville to La Crosse. Greyhound is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 2 | 1d 14h 50m | $184.00 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Greenville to La Crosse every day, with the average journey taking around 38 hours and 50 minutes to complete. Bus tickets for Greyhound trips to La Crosse usually start from $159.
Frequently Asked Questions
The bus takes an average of 38 hours and 50 minutes to cover the 778 miles from Greenville to La Crosse. However, the fastest bus only takes 38 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 11:00pm and the last bus leaves at 11:00pm. To see the times for all buses from Greenville to La Crosse, enter your specific travel dates in the search bar.
There are usually only 2 buses per day from Greenville to La Crosse. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.
Need more travel options? Consider taking the train from Greenville, SC to La Crosse, WI; ticket prices start at $537.00.
City Information
Greenville
Image credit: Unsplash
Image credit: Unsplash
Image credit: Unsplash
As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
La Crosse
A busy college town blessed with lush and beautiful green zones, La Crosse is one of the best places to just chill out and unwind. The city's star attraction is the Grandad Bluff, which offers a panoramic view of the entire city and the Mississippi River. Hiking up the hill will certainly be a challenge, but the view from the top makes it all worthwhile. While staying in the city, don't miss out on the chance to go on a cruise aboard the La Crosse Queen, a replica paddle steamer, and unwind while enjoying the sunset. For some family fun, head over to the Children's Museum of La Crosse.
La Crosse does have a pretty reputable food scene, with a strong focus on beers and cheese curds. For an upscale dining experience with the best local dishes, The Waterfront Restaurant & Tavern is a local favorite that has a stellar reputation. Or head to the Dublin Square Irish Pub & Eatery for a combination of good foods and drinks.
La Crosse is easily accessible by bus or train, and regional flights operate out of the La Crosse Municipal Airport.
Station Information
Where does the bus leave from in Greenville?
Main departure station: Bus Terminal - 9 Hendrix Dr
The Greyhound bus station on Hendrix Drive is located near the Woodruff Shopping Center on the outskirts of Greenville. The station has limited seating, but staff is on hand to help with any questions or boarding. A couple of shops are within the same parking complex, including a grocery store. If you are looking for something more substantial, Burger King, Mike's Subs, Southwest Grill, and Starbucks are within a short walk on Woodruff Road. Downtown Greenville is about eight miles west of the station, and Five Forks is only three miles east.
All bus stations in Greenville:
Bus Terminal - 9 Hendrix Dr
Where does the bus arrive in La Crosse?
Main arrival station: 314 Jay St
Buses to La Crosse stop at Jay Street in front of the Grand River Station. The aptly-named grand building features arching ceilings, marble decoration, and amenities like seating and vending machines inside. The station is conveniently located in downtown La Crosse with easy access to surrounding hotels, restaurants, and a rental car agency across the street. Bus lines, including Greyhound and Jefferson Lines, connect La Crosse to Minneapolis, Milwaukee, Chicago, and beyond.
All bus stations in La Crosse:
314 Jay St
University of Wisconsin
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