Cheap bus tickets from Mississauga to Buffalo
Find and compare the best ground travel options in one place.
Bus from Mississauga to Buffalo: Journey Information
There are 6 intercity buses per day from Mississauga to Buffalo. Travelling by bus from Mississauga to Buffalo usually takes around 5 hours and 30 minutes, but the fastest Adirondack Trailways bus can make the trip in 2 hours and 45 minutes.
- Distance
- 62 mi (100 km)
- Shortest duration
- 2h 45m
- Cheapest price
- CHF 16.74
- Trips per day
- 6
- Most frequent service
- FlixBus US
- Bus lines
- 3
Millions of travellers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 400+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travellers are saying about Wanderu:
Mississauga to Buffalo Bus Schedule

There are several bus options that can take you from Mississauga to Buffalo:
- Adirondack Trailways: 1 daily bus from CHF 17
- FlixBus US: 4 daily buses from CHF 17
- Greyhound: 3 daily buses from CHF 21
How much is a bus ticket from Mississauga to Buffalo?
Bus tickets for a trip from Mississauga to Buffalo cost about CHF 25 when you book at the cheapest time, 29 days ahead. Opting to take a bus is a wallet-friendly way to make this trip. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Mississauga to Buffalo by travel date
If you're planning to travel by bus from Mississauga to Buffalo in the next month, the average ticket price is expected to range from CHF 23 to CHF 36. The cheapest bus tickets available in the next few weeks are for trips departing on December 9, 2026. If you’re looking to travel to Buffalo this week, bus tickets are available starting at CHF 24.
Average bus ticket prices from Mississauga to Buffalo by month
Taking the bus from Mississauga to Buffalo is usually cheapest in April, when the average ticket price is only CHF 21. If you're planning to take the bus from Mississauga to Buffalo during August, keep in mind that bus ticket prices may be higher than usual, with an average price of CHF 31. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 29 days in advance. This way, you can save up to CHF 8.39 on your bus ticket compared to booking last-minute.
What bus companies travel from Mississauga to Buffalo?
There are 3 bus lines from Mississauga to Buffalo available for you to search and compare on Wanderu. With 4 daily trips, FlixBus US usually has the most buses running on any given day. Here are some time and price comparisons for all the available options:
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Adirondack Trailways | 1 | 2h 45m | CHF 20.61 |
| FlixBus US | 4 | 5h 15m | CHF 29.07 |
| Greyhound | 3 | 6h | CHF 29.98 |
Adirondack Trailways connects areas in New York such as the Adirondacks and Hudson Valley with New York City, serving a total of 94 cities. Some of its top routes include those going to Albany, Ithaca, and Syracuse. Onboard, Adirondack Trailways vehicles have Wi-Fi for internet connectivity on the move and additional amenities, including power outlets, washrooms, air conditioning, overhead lighting, and reclinable seats with footrests.
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 4 trips per day from Mississauga to Buffalo, and the average ticket for this route costs only CHF 29.07.






Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Mississauga to Buffalo every day, with the average journey taking around 6 hours to complete. Bus tickets for Greyhound trips to Buffalo usually start from CHF 21.27.






Frequently asked questions about travelling by bus from Mississauga to Buffalo
There are 6 scheduled buses that travel from Mississauga to Buffalo every day, so you have a decent number of options to choose from. However, only one of these is a direct bus. With direct service, you do not have to transfer onto a different bus at any point during your trip. Direct buses also tend to be significantly faster, which is worth bearing in mind as you compare the available options.
Trips per day
6
Direct trips
1
The bus takes an average of 5 hours and 30 minutes to cover the 100 kilometres from Mississauga to Buffalo. However, the fastest bus only takes 2 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
62
Distance (km)
100
The first bus leaves at 12:10 a.m. and the last bus leaves at 4:55 p.m. To see the times for all buses from Mississauga to Buffalo, enter your specific travel dates in the search bar.
Earliest bus
12:10am
Latest bus
4:55pm
Saturday is usually the day when buses are busiest, as many travellers take the bus to enjoy the weekend in Buffalo. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
Most crowded
Saturday
Least crowded
Thursday
City Information
Buffalo



Buffalo is a great budget destination that will not burn through your pocket. Located less than an hour’s drive from Niagara Falls, the city serves as a transportation hub for tourists who want to marvel at the sights of the famous landmark. Visitors can either enjoy the tour from a boat, or walk around the section behind the falls themselves. If you opt for a more idyllic and peaceful destination instead, Forest Lawn is a good choice. A beautiful cemetery that is far from the hustle and bustle of the big city, the destination is a perfect spot for a picnic. As the day winds down to an end, don’t hesitate to attend a performance at Shea’s Performing Arts Center, which features lavish interiors as well as amazing Broadway shows.
Buffalo’s chicken wings are the city’s trademark dish, and tourists who wish to grab a bite could do so at Duff’s Famous Wings or Anchor Bar. For a wider selection, The Left Bank is an even better option.
The principal bus station in Buffalo is the Metropolitan Transportation Center downtown. Travellers can catch buses by Greyhound, New York Trailways, Fullington Trailways and Barons Bus Lines from this station. The main Amtrak train station in Buffalo is located on Exchange St not too far from the bus station. Buffalo is served by Amtrak’s Empire Service and Maple Leaf lines. The city’s principal airport is the Buffalo Niagara International Airport, which is located in the suburb area of Cheektowaga. The city is also served by the nearby Niagara Falls International Airport.
Station Information
Where does the bus leave from in Mississauga?
Main departure station: Duke of York Blvd. Bus Stop
Buses to Buffalo leave from 3 stations in Mississauga.
All bus stations in Mississauga:
- Duke of York Blvd. Bus Stop
- Toronto Pearson Airport YYZ Terminal 1 Gate A
- 4310 Winston Churchill Blvd
Where does the bus arrive in Buffalo?
Main arrival station: 181 Ellicott Street
These are the two stations where buses may stop when they arrive in Buffalo.
All bus stations in Buffalo:
- 181 Ellicott Street
- Downtown Terminal - 181 Ellicott St
Need a return trip from Buffalo to Mississauga?
Search Bus TicketsPlan your next adventure
More buses from Mississauga
- Brockville to Toronto BusCHF 14+
- Chatham to Toronto Bus
- Kingston to Belleville BusCHF 10+
- Mississauga to London BusCHF 19+
- Ottawa to Toronto BusCHF 28+
- Parry Sound to Barrie BusCHF 18+
- Toronto to Kingston BusCHF 18+
- Toronto to Buffalo BusCHF 19+
- Windsor to Toronto BusCHF 32+
- Carleton Place to Ottawa BusCHF 8+
- Cornwall to Toronto BusCHF 11+
- Kingston to Montreal BusCHF 8+
- North Bay to Toronto BusCHF 41+
- Ottawa to Montreal BusCHF 17+
- Perth to Ottawa BusCHF 10+
- Toronto to Montreal BusCHF 42+
- Toronto to New York BusCHF 80+
Continue by bus from Buffalo
- Buffalo to Toronto BusCHF 18+
- Buffalo, NY to Washington DC BusCHF 73+
- Buffalo to Newark BusCHF 71+
- Buffalo to Ellicottville BusCHF 11+
- Buffalo to New York BusCHF 70+
- Buffalo to Rochester BusCHF 9+
- Buffalo to Akron BusCHF 32+
- Buffalo to Erie BusCHF 18+
- Buffalo to Pittsburgh BusCHF 56+
- Buffalo to Hartford BusCHF 58+
- Buffalo to Boston BusCHF 88+
- Buffalo to Binghamton BusCHF 28+
- Buffalo to Ithaca BusCHF 26+
- Buffalo, NY to Niagara Falls, NY BusCHF 8+
- Buffalo to Syracuse BusCHF 22+
- Buffalo to Columbus BusCHF 44+
- Buffalo to Philadelphia BusCHF 85+
- Buffalo to Providence BusCHF 72+
Check out these popular routes
- Calgary to Edmonton BusCHF 23+
- Vancouver to Seattle BusCHF 36+
- Washington DC to New York, NY BusCHF 33+
- Brooklyn, NY to Washington DC Bus
- New York, NY to Washington DC BusCHF 38+
- New York to Boston BusCHF 42+
- New York to Providence BusCHF 34+
- Providence to New York BusCHF 34+
- Houston to Dallas BusCHF 37+
- Edmonton to Calgary BusCHF 21+
- Montreal to New York BusCHF 77+
- Boston to New York BusCHF 40+
- New York to Montreal BusCHF 74+
- New York to Atlanta BusCHF 106+
- New York to Philadelphia BusCHF 27+
- Philadelphia to New York BusCHF 24+
- Dallas to Houston BusCHF 42+
- Seattle to Vancouver BusCHF 35+

Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.




