Lowest Prices
We partner with the top bus & train carriers to bring you the best deals.
Best Travel Options
We help you find & compare the best buses & trains in one place.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
Journey Information
There are 4 intercity buses per day from San Diego to Mesa. Traveling by bus from San Diego to Mesa usually takes around 12 hours and 33 minutes, but the fastest Greyhound bus can make the trip in 12 hours and 5 minutes.
| Distance | 312 mi (503 km) |
| Shortest duration | 12h 5m |
| Cheapest price | US$45.98 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
What bus companies travel from San Diego to Mesa?
There is one intercity bus company available to search and book on Wanderu that operates from San Diego to Mesa. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 4 | 12h 33m | US$61.12 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 4 bus trips from San Diego to Mesa every day, with the average journey taking around 12 hours and 33 minutes to complete. Bus tickets for Greyhound trips to Mesa usually start from US$46.
Frequently Asked Questions
The bus takes an average of 12 hours and 33 minutes to cover the 503 kilometers from San Diego to Mesa. However, the fastest bus only takes 12 hours and 5 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Friday is the busiest travel day for buses as people head from San Diego to Mesa for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
The first bus leaves at 1:00pm and the last bus leaves at 7:00pm. To see the times for all buses from San Diego to Mesa, enter your specific travel dates in the search bar.
City Information
San Diego
San Diego is known as "America's Finest City" for its sunny weather, white-sand beaches, and dazzling attractions from Belmont Park to SeaWorld. San Diego's 70 miles of pristine beaches include such gems as Mission Beach, Pacific Beach, La Jolla Cove, and Coronado Beach. The city's strong surfing culture may even inspire you to rent a surfboard and catch the epic waves, bro.
Visitors can spend days getting lost in Balboa Park, a 1,200-acre cultural hub which features 16 museums, immaculate gardens, and the world-famous San Diego Zoo. The historic heart of the city, Old Town, showcases San Diego's heritage and ties to Mexican culture, while other sights like the USS Midway pay tribute to the city's military and maritime history. Leave time for some evening exploring, too! San Diego is rated the #1 best city for craft beer in America, so don't miss out on the bars in the Gaslamp Quarter: 16 walkable blocks packed with nightlife and young crowds.
Two airports, as well as many bus and train options, mean it is easy to get to San Diego from afar or from nearby cities like Tijuana, Los Angeles, Phoenix, and Las Vegas.
Station Information
Where does the bus leave from in San Diego?
Main departure station: San Ysidro Transit Center
San Diego has two bus stations with service to Mesa.
All bus stations in San Diego:
San Ysidro Transit Center
San Diego Greyhound Bus Stop
Where does the bus arrive in Mesa?
Main arrival station: Bus Station
All buses from San Diego arrive at one main station in Mesa.
Bus stations in Mesa:
Bus Station
Get around town with Moovit
Need a return trip from Mesa to San Diego?
Search Bus Tickets
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free and with no additional fees. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
Book buses and trains on the go with the Wanderu app.
Download our app and snag the best travel deals across North America & Europe.Learn more