Cheap bus tickets from Orlando to Panama City
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Orlando to Panama City Bus Schedule
Bus from Orlando to Panama City: Journey Information
There are 2 intercity buses per day from Orlando to Panama City. Traveling by bus from Orlando to Panama City usually takes around 9 hours and 27 minutes, but the fastest FlixBus US bus can make the trip in 8 hours and 15 minutes.
| Distance | 281 mi (452 km) |
| Shortest duration | 8h 15m |
| Cheapest price | US$57.97 |
| Most frequent service | FlixBus US |
| Bus lines | 2 |

How much is a bus ticket from Orlando to Panama City?
Bus tickets for a trip from Orlando to Panama City cost US$73.10 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price
Average bus ticket prices from Orlando to Panama City by travel date
Bus tickets from Orlando to Panama City are expected to cost between US$66 and US$122 over the next four weeks. If you're planning a trip to Panama City within the next week, you can find the cheapest bus tickets starting from US$69. Don't wait too long to book your ticket, as prices tend to rise as the travel date approaches.
Monthly avg. prices
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 8 days in advance. This way, you can save up to US$37.79 on your bus ticket compared to booking last-minute.
What bus companies travel from Orlando to Panama City?
There are two bus lines that have daily service from Orlando to Panama City that you can compare and book on Wanderu. Of these two carriers, FlixBus US usually offers more choice, with 2 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 2 | 9h 46m | US$98.29 |
| Greyhound | 1 | 9h 22m | US$81.55 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Orlando to Panama City, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from Orlando to Panama City every day, with the average journey taking around 9 hours and 22 minutes to complete. Bus tickets for Greyhound trips to Panama City usually start from US$58.
Frequently asked questions about traveling by bus from Orlando to Panama City
The bus takes an average of 9 hours and 27 minutes to cover the 452 kilometers from Orlando to Panama City. However, the fastest bus only takes 8 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
"Travelers prefer riding the bus on Saturday to enjoy the weekend in Panama City. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet."
The first bus leaves at 4:00am and the last bus leaves at 12:00pm. To see the times for all buses from Orlando to Panama City, enter your specific travel dates in the search bar.
City Information
Orlando



Orlando is the Theme Park Capital of the World, thanks to the high density of thrilling parks like Walt Disney World, Universal Studios, SeaWorld, LEGOLAND, Gatorland and more. It's no wonder we rated Orlando the #1 travel destination for families. Family vacation or not, if the highlight of your trip is picking out a wand at Ollivanders in the Wizarding World of Harry Potter or finally meeting Elsa in the Magic Kingdom, you know we won't judge.
Winter Park and Thornton Park – not more theme parks, we promise – are trendy neighborhoods where you can experience some of Orlando's world-class shopping, dining, and craft beer. You can also immerse yourself in some of Florida's unique wildlife at Orlando Wetlands Park, or the more central Lake Eola Park downtown. Orlando enjoys an average of 233 days of sunshine a year, so even though it's one of the cheapest cities to visit over Spring Break, you'll soak up that sweet, sweet sun almost any time of year.
Craving the ocean? Head a few hours outside Orlando for some of Florida's gorgeous beaches like New Smyrna Beach, Cocoa Beach, and the Canaveral National Seashore. Two large airports, as well as many bus and train companies with service in the area, mean that traveling from Orlando to other sunny Florida destinations and beyond is a breeze.
Station Information
Where does the bus leave from in Orlando?

Image credit: Mark Goebel
Link to image attributionMain departure station: Bus Terminal - 555 N John Young Pkwy
The Bus Terminal at 555 N John Young Pkwy is the primary Greyhound bus station in Orlando, where travelers can catch a bus to other destinations throughout Florida and beyond. The station is located under 3 miles from downtown Orlando and the nearest SunRail station. There is also a Lynx public bus stop which conveniently drops people off right at the Greyhound Bus Terminal. Open 24 hours a day, the bus station provides vending machines if you need a quick bite, and there are also several fast food options within a short walk to fuel up before your trip.
All bus stations in Orlando:
Bus Terminal - 555 N John Young Pkwy
The Florida Mall
Where does the bus arrive in Panama City?
Main arrival station: Panama City Bch Station
All buses from Orlando arrive at one main station in Panama City.
Bus stations in Panama City:
Panama City Bch Station
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