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Cheap bus tickets from Prague to Milan
Find and compare the best ground travel options in one place.
Bus from Prague to Milan: Journey Information
There are 42 intercity buses per day from Prague to Milan. Traveling by bus from Prague to Milan usually takes around 16 hours and 16 minutes, but the fastest FlixBus bus can make the trip in 12 hours and 35 minutes.
- Distance
- 401 mi (645 km)
- Shortest duration
- 12h 35m
- Cheapest price
- CZK 1,407.81
- Trips per day
- 0
- Most frequent service
- FlixBus
- Bus lines
- 2
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Prague to Milan Bus Schedule
There are several bus options that can take you from Prague to Milan:
See more detailsHow much is a bus ticket from Prague to Milan?
Bus tickets for a trip from Prague to Milan cost CZK 1,768 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Prague to Milan by travel date
If you're planning to travel by bus from Prague to Milan in the next month, the average ticket price is expected to range from CZK 1,602 to CZK 2,792. The cheapest bus tickets available in the next few weeks are for trips departing on October 20, 2026. If you’re looking to travel to Milan this week, bus tickets are available starting at CZK 1,602.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. Booking in advance is the best way to find cheap bus tickets, even if it’s only by a few days.
What bus companies travel from Prague to Milan?
There are two bus lines that have daily service from Prague to Milan that you can compare and book on Wanderu. Of these two carriers, FlixBus usually offers more choice, with 42 scheduled trips per day.
First launched in Germany in 2013, FlixBus has become one of the largest intercity bus companies in Europe. Its fleet travels through nearly every country in Europe, including the U.K. FlixBus operates an average of 42 trips from Prague to Milan, and usually makes the trip in about 16 hours and 17 minutes. On your trip, you'll enjoy Wi-Fi and live GPS, as well as restrooms, air conditioning, and power outlets.
Book RegioJet from Prague to Milan from CZK 1,407.81. There are 2 trips per day offered by RegioJet from Prague to Milan and you can expect on average to pay CZK 1,684.60 for a RegioJet ticket to Milan. In Prague, RegioJet departs to Milan from Prague Florenc Bus Station and one other station. In Milan, RegioJet arrives at Lampugnano.
An average trip on RegioJet from Prague to Milan takes 14 hours and 45 minutes, while the fastest available RegioJet trip will get you to Milan in 14 hours.
Frequently asked questions about traveling by bus from Prague to Milan
There are 42 scheduled buses that travel from Prague to Milan every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.
Trips per day
42
Direct trips
0
The bus takes an average of 16 hours and 16 minutes to cover the 401 miles from Prague to Milan. However, the fastest bus only takes 12 hours and 35 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
401
Distance (km)
645
The first bus leaves at 2:30 AM and the last bus leaves at 11:50 PM. To see the times for all buses from Prague to Milan, enter your specific travel dates in the search bar.
Earliest bus
2:30am
Latest bus
11:50pm
Friday is the busiest travel day for buses as people head from Prague to Milan for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
Most crowded
Friday
Least crowded
Tuesday
City Information
Prague
With storied churches and beautiful castles, Prague was once the hidden gem of Europe, and it has now revealed its beauty to the world. Prague’s prized landmark is the majestic Prague Castle, which is the largest castle complex in the world. The castle is an amalgamation of many different architectural styles, making it a very special destination to visit. You might even get to see the president of Czechia as well, since it is his office! If you simply want to stroll around and enjoy the vibe of the city, head for the Old Town Square, which has seen very few changes since its conception in the 12th century. If you are not afraid of a little hiking, head to Petrin Hill, which is one of the largest green areas in the city. The area also houses the Rose Garden and Seminary Garden, featuring more than 2,100 trees.
Prague’s food scene is not as well-known as other famous cities’, but the local dishes such as knedlíky or bramboráky will pleasantly surprise you. La Degustation Boheme Bourgeoise is a Michelin-starred restaurant that offers amazing Czech dishes. For local beers, don’t hesitate to check out U Medvídku.
Praha hlavní nádraží is the largest international train station in Prague and it’s located right in the heart of the city. Not too far from the train station is Prague’s central bus station. The principal airport in the city is the Václav Havel Airport Prague.
Milan
The fashion capital of the world, Milan, is a busy city brimming with activities and lavish nightlife. In spite of its frenetic modern lifestyle, Milan is also blessed with some amazing landmarks, of which the Milan Cathedral should be given special attention. Considered the largest and most unique Gothic structure in Italy, the cathedral took about 600 years to build, and its impressive gothic details will amaze all fans of architecture. The roof of the cathedral itself is accessible, so visitors can climb up to marvel at the city’s skyline and see the cathedral’s details up close. Another spot to consider is the Santa Maria delle Grazie, which currently houses “The Last Supper,” a masterpiece by the legendary artist Leonardo da Vinci. For those who enjoy old books, the Ambrosiana Library & Picture Gallery houses a vast collection of artworks, as well as rare ancient manuscripts.
For a taste of the unique Milanese cuisine, you could consider the Gente di Mare in Darsena, which offers superb seafood. If you wish to enjoy great local pizzas, Pizzium—Via Vigevano offers great dishes.
Milano Centrale is the city’s main train station, offering access to international destinations such as Berlin, Frankfurt and Munich. The main bus station in Milan is Lampugnano, serving as the local hub for bus carriers like FlixBus, BlaBlaCar Bus and Union Ivkoni. The main airport in Milan is Malpensa Airport located about 32 miles northwest of the city center.
Station Information
Where does the bus leave from in Prague?
Main departure station: Prague Florenc Bus Station
Prague Florenc Central Bus Station is the city's largest and busiest bus station. The station complex is fully equipped with all the modern amenities you could ask for, including information services, luggage storage, public toilets, restaurants, and shops. Bus lines including FlixBus and RegioJet stop at the station, and Prague's central train station is less than 2km away for connections to rail travel. Right outside the bus station, you'll find the Florenc Metro stop, a hotel, several restaurants, and excellent shopping.
All bus stations in Prague:
- Prague Florenc Bus Station
- Central Bus Station
- Aviatická 1017/2
- Prague Anděl Ostrovského 34/1
- Zličín
- kancelář u nástupiště č. 6
- Hradčanská
- Tomíčkova
Where does the bus arrive in Milan?
Main arrival station: Lampugnano
The Lampugnano Bus Station is a major station in Milan. It is located on Via Giulio Natta, at the base of Monte Stella, and close to amenities such as coffee shops and restaurants. There is an indoor space to wait for your bus, but there is also outdoor seating under a wide covered area where buses board. The station is usually busy, as it welcomes many buses; FlixBus, BlaBlaCar Bus, RegioJet, Union Ivkoni, and Itabus are just a few. Though the station is located northwest of Milan's city center in the Lampugnano district, it is easy to reach other areas thanks to the metro stop right next door to the bus station.
All bus stations in Milan:
- Lampugnano
- Milan (San Donato M3)
- Lampugnano
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