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Cheap bus tickets from Tlaquepaque to Mexico City
Find and compare the best ground travel options in one place.
Bus from Tlaquepaque to Mexico City: Journey Information
There are 15 intercity buses per day from Tlaquepaque to Mexico City. Traveling by bus from Tlaquepaque to Mexico City usually takes around 7 hours and 17 minutes, but the fastest ETN bus can make the trip in 6 hours and 30 minutes.
- Distance
- 284 mi (457 km)
- Shortest duration
- 6h 30m
- Cheapest price
- RON 460.05
- Trips per day
- 15
- Most frequent service
- ETN
- Bus lines
- 1
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Tlaquepaque to Mexico City Bus Schedule
There are several bus options that can take you from Tlaquepaque to Mexico City:
See more detailsHow much is a bus ticket from Tlaquepaque to Mexico City?
Bus tickets for a trip from Tlaquepaque to Mexico City cost about RON 460 when you book at the cheapest time, 25 days ahead. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Tlaquepaque to Mexico City by travel date
If you're planning to travel by bus from Tlaquepaque to Mexico City in the next month, the average ticket price is expected to range from RON 460 to RON 479. The cheapest bus tickets available in the next few weeks are for trips departing on November 26, 2026. If you’re looking to travel to Mexico City this week, bus tickets are available starting at RON 465.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 25 days in advance. This way, you can save up to RON 23.96 on your bus ticket compared to booking last-minute.
What bus companies travel from Tlaquepaque to Mexico City?
There is one intercity bus company available to search and book on Wanderu that operates from Tlaquepaque to Mexico City. ETN connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| ETN | 15 | 7h 17m | RON 474.36 |
Book ETN from Tlaquepaque to Mexico City from RON 460.05. There are 15 trips per day offered by ETN from Tlaquepaque to Mexico City and you can expect on average to pay RON 474.36 for a ETN ticket to Mexico City. In Tlaquepaque, ETN departs to Mexico City from Guadalajara Central Bus Station. In Mexico City, ETN arrives at Central de Autobuses and one other station.
An average trip on ETN from Tlaquepaque to Mexico City takes 7 hours and 17 minutes, while the fastest available ETN trip will get you to Mexico City in 6 hours and 30 minutes.
On weekends, ETN offers 15 trips per day. A one way ticket costs RON 460.05 for a weekend trip to Mexico City.
Frequently asked questions about traveling by bus from Tlaquepaque to Mexico City
There are 15 scheduled buses that travel from Tlaquepaque to Mexico City every day, so you have a decent number of options to choose from. Furthermore, all of these are direct buses which you can take the entire route from Tlaquepaque to Mexico City without transferring.
Trips per day
15
Direct trips
15
The bus takes an average of 7 hours and 17 minutes to cover the 284 miles from Tlaquepaque to Mexico City. However, the fastest bus only takes 6 hours and 30 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
284
Distance (km)
457
The first bus leaves at 12:00 AM and the last bus leaves at 11:59 PM. To see the times for all buses from Tlaquepaque to Mexico City, enter your specific travel dates in the search bar.
Earliest bus
12:00am
Latest bus
11:59pm
Friday is the busiest travel day for buses as people head from Tlaquepaque to Mexico City for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
Most crowded
Friday
Least crowded
Wednesday
City Information
Mexico City
Mexico City is one of the most vibrant and liveliest cities in the world, making it an exciting destination for all travelers. One of the must-see attractions in the city is the famous Museo Nacional de Antropología, which features an extensive collection from the city’s pre-Columbian era. Its star attraction is the famous Aztec Calendar Stone, also known as Piedra del Sol. For those who enjoy exploring the city’s amazing cultural life, the Palacio de Bellas Artes is a must-see destination. The art deco-style palace hosts some of the grandest cultural events around, including concerts, operas, etc. Another unique destination to check out is Teotihuacán, a world heritage site that contains some of the largest pre-Columbian pyramids in Mexico.
Mexico City’s food scene is so vast that it can be quite hard to fully explore in just a few days. Some notable foodie destinations include Pujol, Contramar, and Quintonil. If you want to grab one of those famous Mexican churros, head over to Churreria El Moro.
Mexico City’s four major bus stations are North, South, Observatorio, and TAPO. Some intercity buses leave directly from the Mexico City International Airport, which is located just about 7 miles east of the city center.
Station Information
Where does the bus leave from in Tlaquepaque?
Main departure station: Guadalajara Central Bus Station
Most buses depart from the main station in Tlaquepaque.
All bus stations in Tlaquepaque:
- Guadalajara Central Bus Station
Where does the bus arrive in Mexico City?
Main arrival station: Central de Autobuses
The bus station on Eje Central Lázaro Cárdenas is a curbside stop where intercity and local buses connect to the Lázaro Cárdenas metro station. The metro station is located on Line 9 of the local metro system and includes all the basic amenities of a public station: public restrooms, ATMs, and a waiting area with roofs. The aboveground bus station is at the intersection of Eje Central Lázaro Cárdenas and Eje 3 in Mexico City. The intersection has a supermarket, and the surrounding blocks are home to many eateries and retail stores.
All bus stations in Mexico City:
- Central de Autobuses
- Mexico City Calz Taxquena
Need a return trip from Mexico City to Tlaquepaque?
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