Cheap bus tickets from Acayucan to Mexico City
Find and compare the best ground travel options in one place.
Bus from Acayucan to Mexico City: Journey Information
There are 34 intercity buses per day from Acayucan to Mexico City. Traveling by bus from Acayucan to Mexico City usually takes around 9 hours and 6 minutes, but the fastest ADO bus can make the trip in 8 hours and 15 minutes.
| Distance | 294 mi (474 km) |
| Shortest duration | 8h 15m |
| Cheapest price | $59.00 |
| Trips per day | 34 |
| Most frequent service | ADO |
| Bus lines | 4 |
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Acayucan to Mexico City Bus Schedule

There are several bus options that can take you from Acayucan to Mexico City:
- ADO: 22 daily buses from $77
- AU: 6 daily buses from $59
- ADO GL: 5 daily buses from $95
- ADO OCC: 1 daily bus from $77
How much is a bus ticket from Acayucan to Mexico City?
Bus tickets for a trip from Acayucan to Mexico City cost $77.91 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Acayucan to Mexico City by travel date
If you're planning to travel by bus from Acayucan to Mexico City in the next month, the average ticket price is expected to range from $78 to $80. The cheapest bus tickets available in the next few weeks are for trips departing on August 30, 2026. If you’re looking to travel to Mexico City this week, bus tickets are available starting at $78.
Average bus ticket prices from Acayucan to Mexico City by month
Taking the bus from Acayucan to Mexico City is usually cheapest in May, when the average ticket price is only $71. If you're planning to take the bus from Acayucan to Mexico City during December, keep in mind that bus ticket prices may be higher than usual, with an average price of $76. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 9 days in advance. This way, you can save up to $0.36 on your bus ticket compared to booking last-minute.
What bus companies travel from Acayucan to Mexico City?
There are multiple buses that travel from Acayucan to Mexico City, including ADO, AU, ADO GL, ADO OCC. Here is what you should know about the 4 most popular bus lines:
| BUS | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| ADO | 22 | 9h 4m | $78.15 |
| AU | 6 | 9h 18m | $60.37 |
| ADO GL | 5 | 8h 59m | $96.32 |
| ADO OCC | 1 | 9h 29m | $78.22 |
Book ADO from Acayucan to Mexico City from $77. There are 22 trips per day offered by ADO from Acayucan to Mexico City and you can expect on average to pay $78.15 for a ADO ticket to Mexico City. In Acayucan, ADO departs to Mexico City from Acayucan Bus Station. In Mexico City, ADO arrives at Mexico City TAPO San Lazaro Bus Station and one other station.
An average trip on ADO from Acayucan to Mexico City takes 9 hours and 4 minutes, while the fastest available ADO trip will get you to Mexico City in 8 hours and 15 minutes.
On weekends, ADO offers 23 trips per day. A one way ticket costs $77 for a weekend trip to Mexico City.
Book AU from Acayucan to Mexico City from $59. There are 6 trips per day offered by AU from Acayucan to Mexico City and you can expect on average to pay $60.37 for a AU ticket to Mexico City. In Acayucan, AU departs to Mexico City from Acayucan Bus Station. In Mexico City, AU arrives at Mexico City TAPO San Lazaro Bus Station and one other station.
An average trip on AU from Acayucan to Mexico City takes 9 hours and 18 minutes, while the fastest available AU trip will get you to Mexico City in 8 hours and 30 minutes.
On weekends, AU offers 6 trips per day. A one way ticket costs $59 for a weekend trip to Mexico City.
ADO GL is a prominent Mexican passenger bus company that has been operating since 1992. It is part of the renowned ADO group and focuses on luxury travel, primarily serving Mexico's southern and eastern regions, including the Gulf of Mexico and the Yucatan Peninsula. ADO GL offers deluxe coaches with executive-style seats, ample legroom, and various amenities such as air conditioning, restrooms, power outlets, and beverage services, providing a truly luxurious experience for passengers.
Book ADO OCC from Acayucan to Mexico City from $77. Typically there is one ADO OCC schedule per day from Acayucan to Mexico City and you can expect on average to pay $78.22 for a ADO OCC ticket to Mexico City. In Acayucan, ADO OCC departs to Mexico City from Acayucan Bus Station. In Mexico City, ADO OCC arrives at Central de Autobuses and one other station.
An average trip on ADO OCC from Acayucan to Mexico City takes 9 hours and 29 minutes, while the fastest available ADO OCC trip will get you to Mexico City in 8 hours and 40 minutes.
On weekends, ADO OCC offers 1 trip per day and you could expect to pay $77 for a one way ticket for your weekend getaway trip to Mexico City.
Frequently asked questions about traveling by bus from Acayucan to Mexico City
There are 34 scheduled buses that travel from Acayucan to Mexico City every day, so you have a decent number of options to choose from. Furthermore, all of these are direct buses which you can take the entire route from Acayucan to Mexico City without transferring.
TRIPS PER DAY
34
DIRECT TRIPS
34
The bus takes an average of 9 hours and 6 minutes to cover the 294 miles from Acayucan to Mexico City. However, the fastest bus only takes 8 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
DISTANCE (MI)
294
DISTANCE (KM)
474
The first bus leaves at 12:15am and the last bus leaves at 11:15pm. To see the times for all buses from Acayucan to Mexico City, enter your specific travel dates in the search bar.
EARLIEST BUS
12:15am
LATEST BUS
11:15pm
Sunday tends to be the busiest day for buses, as many passengers take the bus to Mexico City at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
MOST CROWDED
Sunday
LEAST CROWDED
Monday
City Information
Mexico City



Mexico City is one of the most vibrant and liveliest cities in the world, making it an exciting destination for all travelers. One of the must-see attractions in the city is the famous Museo Nacional de Antropología, which features an extensive collection from the city’s pre-Columbian era. Its star attraction is the famous Aztec Calendar Stone, also known as Piedra del Sol. For those who enjoy exploring the city’s amazing cultural life, the Palacio de Bellas Artes is a must-see destination. The art deco-style palace hosts some of the grandest cultural events around, including concerts, operas, etc. Another unique destination to check out is Teotihuacán, a world heritage site that contains some of the largest pre-Columbian pyramids in Mexico.
Mexico City’s food scene is so vast that it can be quite hard to fully explore in just a few days. Some notable foodie destinations include Pujol, Contramar, and Quintonil. If you want to grab one of those famous Mexican churros, head over to Churreria El Moro.
Mexico City’s four major bus stations are North, South, Observatorio, and TAPO. Some intercity buses leave directly from the Mexico City International Airport, which is located just about 7 miles east of the city center.
Station Information
Where does the bus leave from in Acayucan?
Main departure station: Acayucan Bus Station
Most buses depart from the main station in Acayucan.
All bus stations in Acayucan:
- Acayucan Bus Station
Where does the bus arrive in Mexico City?
Main arrival station: Central de Autobuses
The bus station on Eje Central Lázaro Cárdenas is a curbside stop where intercity and local buses connect to the Lázaro Cárdenas metro station. The metro station is located on Line 9 of the local metro system and includes all the basic amenities of a public station: public restrooms, ATMs, and a waiting area with roofs. The aboveground bus station is at the intersection of Eje Central Lázaro Cárdenas and Eje 3 in Mexico City. The intersection has a supermarket, and the surrounding blocks are home to many eateries and retail stores.
All bus stations in Mexico City:
- Central de Autobuses
- Mexico City TAPO San Lazaro Bus Station
- Mexico City TAPO San Lazaro
- La Terminal de Autobuses de Pasajeros de Oriente (TAPO)
Need a return trip from Mexico City to Acayucan?
Search Bus Tickets
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu's simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.




