Cheap bus tickets from Jacksonville to Knoxville
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Bus from Jacksonville to Knoxville: Journey Information
There are 2 intercity buses per day from Jacksonville to Knoxville. Traveling by bus from Jacksonville to Knoxville usually takes around 17 hours and 20 minutes, but the fastest FlixBus US bus can make the trip in 12 hours and 45 minutes.
| Distance | 410 mi (660 km) |
| Shortest duration | 12h 45m |
| Cheapest price | $118.97 |
| Trips per day | 0 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |
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Jacksonville to Knoxville Bus Schedule
There are several bus options that can take you from Jacksonville to Knoxville:
See more detailsHow much is a bus ticket from Jacksonville to Knoxville?
Bus tickets for a trip from Jacksonville to Knoxville cost $119.64 on average. Bus tickets on this route can be a bit expensive due to the length of the trip. But even with a higher price tag, taking the bus is often more affordable than flying to Knoxville. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Jacksonville to Knoxville by travel date
If you're planning to travel by bus from Jacksonville to Knoxville in the next month, the average ticket price is expected to range from $126 to $163. The cheapest bus tickets available in the next few weeks are for trips departing on September 1, 2026. If you’re looking to travel to Knoxville this week, bus tickets are available starting at $162.
Average bus ticket prices from Jacksonville to Knoxville by month
Taking the bus from Jacksonville to Knoxville is usually cheapest in September, when the average ticket price is only $123. If you're planning to take the bus from Jacksonville to Knoxville during December, keep in mind that bus ticket prices may be higher than usual, with an average price of $191. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 13 days in advance. This way, you can save up to $96.09 on your bus ticket compared to booking last-minute.
What bus companies travel from Jacksonville to Knoxville?
There are multiple buses that travel from Jacksonville to Knoxville, including FlixBus US. Here is what you should know about the 1 most popular bus lines:
| BUS | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 2 | 17h 20m | $193.99 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Jacksonville to Knoxville, and the average ticket for this route costs only $193.99.
Frequently asked questions about traveling by bus from Jacksonville to Knoxville
There are usually only 2 buses per day from Jacksonville to Knoxville. However, neither bus offers direct service, so you will have to get off your original vehicle to transfer buses during the trip.
TRIPS PER DAY
2
DIRECT TRIPS
0
The bus takes an average of 17 hours and 20 minutes to cover the 410 miles from Jacksonville to Knoxville. However, the fastest bus only takes 12 hours and 45 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
DISTANCE (MI)
410
DISTANCE (KM)
660
The first bus leaves at 9:05am and the last bus leaves at 11:15pm. To see the times for all buses from Jacksonville to Knoxville, enter your specific travel dates in the search bar.
EARLIEST BUS
9:05am
LATEST BUS
11:15pm
Friday is the busiest travel day for buses as people head from Jacksonville to Knoxville for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
MOST CROWDED
Friday
LEAST CROWDED
Wednesday
City Information
Jacksonville
Jacksonville, or simply "Jax," is the largest city by area in the continental United States. Located in the northeastern corner of Florida, this sunny city along the St Johns River also boasts 22 miles of beaches along the Atlantic Ocean, coastal cuisine, and many historic neighborhoods to explore.
Natural beauty is king in Jacksonville, and where better to soak in some of the Sunshine State's outdoor wonders than the beach? Try Little Talbot Island for beachcombing or fishing, Big Talbot Island for exploring wetlands and marshes, and Kathryn Abbey Hanna Park for surfing. If you don't have the patience for birdwatching in the wild, the Jacksonville Zoo and Gardens will let you get up-close and personal with over 2,400 animals.
To take a break from the sun's rays, head indoors to one of Jacksonville's many eclectic museums. The Cummer Museum of Art and Gardens combines European-inspired gardens with an impressive collection of fine art, while the Museum of Science and History is worth a stop for its planetarium alone. On Saturdays, you wouldn’t want to miss the Riverside Arts Market where artisans and farmers set up stalls along the river, and you can catch live music, food trucks and even free yoga.
Jacksonville is easily accessed by air, train, or bus, and connects Florida to locations throughout the South. Amtrak's Jacksonville train station is located in the northern outskirts of the city, and most bus service in and out of Jacksonville conveniently departs from the JTA Intercity Bus Terminal in the heart of downtown.
Station Information
Where does the bus leave from in Jacksonville?
Main departure station: JTA Intercity Bus Terminal
The modern, light-filled Intercity Bus Terminal at 1111 W Forsyth Street in Jacksonville helps travelers reach destinations throughout Florida and the Southern United States. Bus service to and from Jacksonville’s primary station is operated by Red Coach, Greyhound, and Jefferson Lines. The station is located in the downtown business district and, as the city’s central transportation hub, includes connections to the Skyway monorail as well as rental bike services and taxi services. You’ll find a cafe and grill onsite so you can grab a meal or take snacks to go.
All bus stations in Jacksonville:
- JTA Intercity Bus Terminal
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Jacksonville arrive at one main station in Knoxville.
All bus stations in Knoxville:
- Knoxville Bus Station
Need a return trip from Knoxville to Jacksonville?
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