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Cheap bus tickets from Durham, NC to Florence, SC
Find and compare the best ground travel options in one place.
Bus from Durham, NC to Florence, SC: Journey Information
There is one daily bus from Durham, NC to Florence, SC. Traveling by bus from Durham, NC to Florence, SC usually takes around 4 hours and 11 minutes, but the fastest Wanda Coach bus can make the trip in 3 hours and 40 minutes.
- Distance
- 134 mi (215 km)
- Shortest duration
- 3h 40m
- Cheapest price
- RON 184.36
- Trips per day
- 1
- Most frequent service
- Wanda Coach
- Bus lines
- 2
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Durham, NC to Florence, SC Bus Schedule
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Average score for buses from Durham, NC to Florence, SC (Based on 1 rating and review)
5.0
There are several bus options that can take you from Durham, NC to Florence, SC:
See more detailsHow much is a bus ticket from Durham, NC to Florence, SC?
Bus tickets for a trip from Durham, NC to Florence, SC cost about RON 270 when you book at the cheapest time, 9 days ahead. Tickets cheaper than RON 270 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Durham, NC to Florence, SC by travel date
If you're planning to travel by bus from Durham, NC to Florence, SC in the next month, the average ticket price is expected to range from RON 278 to RON 288. The cheapest bus tickets available in the next few weeks are for trips departing on November 7, 2026. If you’re looking to travel to Florence, SC this week, bus tickets are available starting at RON 278.
Average bus ticket prices from Durham, NC to Florence, SC by month
Traveling from Durham, NC to Florence, SC by bus will cost you about the same throughout the year. In general, bus ticket prices for this route are fairly consistent, so expect to pay around RON 288 whenever you decide to travel.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 9 days in advance. This way, you can save up to RON 58.75 on your bus ticket compared to booking last-minute.
What bus companies travel from Durham, NC to Florence, SC?
There are two bus lines that have daily service from Durham, NC to Florence, SC that you can compare and book on Wanderu. However, each company only runs one bus per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 8h 30m | RON 287.49 |
| Wanda Coach | 1 | 3h 40m | RON 285.09 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trip per day from Durham, NC to Florence, SC, and the average ticket for this route costs only RON 287.49.
Wanda Coach is one of the leading Chinatown bus carriers in the U.S. The company offers 1 daily bus trip to and from more than 70 cities across the East Coast and the Midwest. With bus ticket prices starting from RON 285.09 and convenient pick-up and drop-off locations, Wanda Coach is one of the preferred bus carriers for passengers looking to travel between the Chinatown districts of Durham, NC and Florence, SC.
Frequently asked questions about traveling by bus from Durham, NC to Florence, SC
There is usually only one bus per day from Durham, NC to Florence, SC. Fortunately, this happens to be a direct bus, meaning that you do not have to get on a different bus at any point during your trip. Need more travel options? Consider taking the train from Durham, NC to Florence, SC; ticket prices start at RON 235.
Trips per day
1
Direct trips
1
The bus takes an average of 4 hours and 11 minutes to cover the 134 miles from Durham, NC to Florence, SC. However, the fastest bus only takes 3 hours and 40 minutes. In other words, you'll have plenty of time to rest and relax on the road. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
134
Distance (km)
215
There is usually only one bus per day from Durham, NC to Florence, SC. It leaves the station in Durham, NC at 9:15 PM each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
Earliest bus
4:20am
Latest bus
9:15pm
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
Most crowded
Thursday
Least crowded
Monday
City Information
Durham
Durham is a little treasure cove for all fans of history and the United States’ heritage. The first and foremost thing you should try out is go on a hike on one of the city’s iconic trails. For a more traditional hiking experience, try the Eno River Trail. If you wish to enjoy a more unique experience, the American Tobacco Trail will be a better choice, as it follows the old CSX railroad. For those who want to explore the city’s rich history, check out the Stagville Plantation, which is now a museum dedicated to the city’s antebellum history, offering a unique historical perspective.
Durham’s food scene is vibrant and exciting. Fans of seafood will definitely be amazed at how fresh and delicious the seafood at Mateo Bar de Tapas is. If you wish to try out Italian eats with a twist, check out Devil’s Pizzeria & Restaurant.
The main bus station is the Transportation Center located at 515 W Pettigrew St in Downtown Durham. From there, you can take a bus to New York, Richmond, Washington D.C., and dozens of other destinations across the country. The main Amtrak train station in Durham is located around the corner from the bus stop at 601 W Main St. Durham is served by Amtrak’s Carolinian and Piedmont lines. The city’s air services are handled by the Raleigh-Durham International Airport, 12 miles southeast of the city.
Florence
Florence is a hidden gem in the northeast of South Carolina. Though best known for its history as a significant railway hub, Florence is a modern city with activities and sights to fill a weekend getaway or a longer vacation.
Every November, Florence goes nuts during the SC Pecan Music and Food Festival, an event hosted downtown to celebrate the beloved pecan. If you're in town during the festival, check out the car show, live music, half marathon, and other associated events to get to know Florence locals and culture.
Florence is a year-round destination for outdoor recreation. Golf is a favorite among Florence residents, so upgrade from mini-golf and try the real thing. Traces Golf Club welcomes golfers of all skill levels, don't worry. Don't leave Florence without spending a day at Lynches River County Park, the starting point of the 66-mile South Carolina Revolutionary Rivers Trail. You can kayak or canoe throughout the county, following the swampy path that allowed American patriots to evade British troops in the American Revolution.
Florence Regional Airport operates limited flights to connect to Charlotte, but most paths to Florence involve some kind of ground travel. Amtrak's Palmetto and Silver Service trains stop in Florence, with connections to New York and Washington to the north and Orlando and Miami to the south. Greyhound and Southeastern Stages offer intercity bus service to Florence that connects the city to other destinations throughout the South.
Station Information
Where does the bus leave from in Durham, NC?
Main departure station: 2724 Guess Rd
Durham, NC has two bus stations with service to Florence, SC.
All bus stations in Durham, NC:
- 2724 Guess Rd
- Bus Terminal - 515 W Pettigrew St
Where does the bus arrive in Florence, SC?
Main arrival station: 2301 W Lucas St (TA Gas Station)
All buses from Durham, NC arrive at one main station in Florence, SC.
All bus stations in Florence, SC:
- 2301 W Lucas St (TA Gas Station)
Need a return trip from Florence, SC to Durham, NC?
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