Cheap bus tickets from Buffalo to Mississauga
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Bus from Buffalo to Mississauga: Journey Information
There are 5 intercity buses per day from Buffalo to Mississauga. Traveling by bus from Buffalo to Mississauga usually takes around 6 hours, but the fastest Adirondack Trailways bus can make the trip in 2 hours and 10 minutes.
- Distance
- 62 mi (100 km)
- Shortest duration
- 2h 10m
- Cheapest price
- RON 98.14
- Trips per day
- 5
- Most frequent service
- FlixBus US
- Bus lines
- 3
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Buffalo to Mississauga Bus Schedule

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Average score for buses from Buffalo to Mississauga (Based on 1 rating and review)
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There are several bus options that can take you from Buffalo to Mississauga:
- Adirondack Trailways: 2 daily buses from RON 96
- FlixBus US: 3 daily buses from RON 93
- Greyhound: 2 daily buses from RON 124
How much is a bus ticket from Buffalo to Mississauga?
Bus tickets for a trip from Buffalo to Mississauga cost about RON 143 when you book at the cheapest time, 17 days ahead. Opting to take a bus is a wallet-friendly way to make this trip. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Buffalo to Mississauga by travel date
If you're planning to travel by bus from Buffalo to Mississauga in the next month, the average ticket price is expected to range from RON 105 to RON 177. The cheapest bus tickets available in the next few weeks are for trips departing on December 2, 2026. If you’re looking to travel to Mississauga this week, bus tickets are available starting at RON 134.
Average bus ticket prices from Buffalo to Mississauga by month
Taking the bus from Buffalo to Mississauga is usually cheapest in March, when the average ticket price is only RON 125. If you're planning to take the bus from Buffalo to Mississauga during August, keep in mind that bus ticket prices may be higher than usual, with an average price of RON 177. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 17 days in advance. This way, you can save up to RON 110.70 on your bus ticket compared to booking last-minute.
What bus companies travel from Buffalo to Mississauga?
There are 3 bus lines from Buffalo to Mississauga available for you to search and compare on Wanderu. With 3 daily trips, FlixBus US usually has the most buses running on any given day. Here are some time and price comparisons for all the available options:
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Adirondack Trailways | 2 | 2h 15m | RON 120.75 |
| FlixBus US | 3 | 6h 18m | RON 177.77 |
| Greyhound | 2 | 5h 37m | RON 185.03 |
Adirondack Trailways connects areas in New York such as the Adirondacks and Hudson Valley with New York City, serving a total of 94 cities. Some of its top routes include those going to Albany, Ithaca, and Syracuse. Onboard, Adirondack Trailways vehicles have Wi-Fi for internet connectivity on the move and additional amenities, including power outlets, restrooms, air conditioning, overhead lighting, and reclinable seats with footrests.
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 3 trips per day from Buffalo to Mississauga, and the average ticket for this route costs only RON 177.77.






Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Buffalo to Mississauga every day, with the average journey taking around 5 hours and 37 minutes to complete. Bus tickets for Greyhound trips to Mississauga usually start from RON 124.45.






Frequently asked questions about traveling by bus from Buffalo to Mississauga
There are 5 scheduled buses that travel from Buffalo to Mississauga every day, so you have a decent number of options to choose from. This includes 2 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip.
Trips per day
5
Direct trips
2
The bus takes an average of 6 hours to cover the 62 miles from Buffalo to Mississauga. However, the fastest bus only takes 2 hours and 10 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
62
Distance (km)
100
The first bus leaves at 4:20 AM and the last bus leaves at 7:00 PM. To see the times for all buses from Buffalo to Mississauga, enter your specific travel dates in the search bar.
Earliest bus
4:20am
Latest bus
7:00pm
Friday is the busiest travel day for buses as people head from Buffalo to Mississauga for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
Most crowded
Friday
Least crowded
Wednesday
City Information
Buffalo



Buffalo is a great budget destination that will not burn through your pocket. Located less than an hour’s drive from Niagara Falls, the city serves as a transportation hub for tourists who want to marvel at the sights of the famous landmark. Visitors can either enjoy the tour from a boat, or walk around the section behind the falls themselves. If you opt for a more idyllic and peaceful destination instead, Forest Lawn is a good choice. A beautiful cemetery that is far from the hustle and bustle of the big city, the destination is a perfect spot for a picnic. As the day winds down to an end, don’t hesitate to attend a performance at Shea’s Performing Arts Center, which features lavish interiors as well as amazing Broadway shows.
Buffalo’s chicken wings are the city’s trademark dish, and tourists who wish to grab a bite could do so at Duff’s Famous Wings or Anchor Bar. For a wider selection, The Left Bank is an even better option.
The principal bus station in Buffalo is the Metropolitan Transportation Center downtown. Travelers can catch buses by Greyhound, New York Trailways, Fullington Trailways and Barons Bus Lines from this station. The main Amtrak train station in Buffalo is located on Exchange St not too far from the bus station. Buffalo is served by Amtrak’s Empire Service and Maple Leaf lines. The city’s principal airport is the Buffalo Niagara International Airport, which is located in the suburb area of Cheektowaga. The city is also served by the nearby Niagara Falls International Airport.
Station Information
Where does the bus leave from in Buffalo?
Main departure station: 181 Ellicott Street
Buffalo has two bus stations with service to Mississauga.
All bus stations in Buffalo:
- 181 Ellicott Street
- Downtown Terminal - 181 Ellicott St
Where does the bus arrive in Mississauga?
Main arrival station: Duke of York Blvd. Bus Stop
Buses arrive in Mississauga at 3 stations, depending on which bus line you are traveling with.
All bus stations in Mississauga:
- Duke of York Blvd. Bus Stop
- 4310 Winston Churchill Blvd
- Toronto Pearson Airport YYZ Terminal 1 Gate A
Need a return trip from Mississauga to Buffalo?
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