Cheap bus tickets from Cleveland to Knoxville
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Cleveland to Knoxville Bus Schedule
Bus from Cleveland to Knoxville: Journey Information
There are 2 intercity buses per day from Cleveland to Knoxville. Traveling by bus from Cleveland to Knoxville usually takes around 19 hours and 38 minutes, but the fastest Greyhound bus can make the trip in 14 hours,
| Distance | 401 mi (645 km) |
| Shortest duration | 14h 0m |
| Cheapest price | NOK 590.99 |
| Most frequent service | Greyhound |
| Bus lines | 1 |

How much is a bus ticket from Cleveland to Knoxville?
Bus tickets for a trip from Cleveland to Knoxville cost NOK 818.72 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Cleveland to Knoxville by travel date
Over the next four weeks, the average price of bus tickets from Cleveland to Knoxville is expected to be between NOK 708 and NOK 1,425. The cheapest day to travel in the next month is November 18, 2025, when tickets are available for November 18, 2025. The cheapest bus tickets available in the next week start at just NOK 708.
Average bus ticket prices from Cleveland to Knoxville by month
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 25 days in advance. This way, you can save up to NOK 476.78 on your bus ticket compared to booking last-minute.
What bus companies travel from Cleveland to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Cleveland to Knoxville. Greyhound is the one bus line that serves this route. Although it's the sole option, there are a couple of different scheduled times to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 2 | 19h 38m | NOK 882.70 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Cleveland to Knoxville every day, with the average journey taking around 19 hours and 38 minutes to complete. Bus tickets for Greyhound trips to Knoxville usually start from NOK 591.
Frequently asked questions about traveling by bus from Cleveland to Knoxville
The bus takes an average of 19 hours and 38 minutes to cover the 401 miles from Cleveland to Knoxville. However, the fastest bus only takes 14 hours. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Because many passengers travel from Cleveland to Knoxville at the beginning of the work week, Monday is usually the busiest day for buses. If you are planning to travel on a Monday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Friday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Friday ticket is the way to go.
The first bus leaves at 2:00am and the last bus leaves at 4:00pm. To see the times for all buses from Cleveland to Knoxville, enter your specific travel dates in the search bar.
City Information
Cleveland



An industrial powerhouse in the past eras, Cleveland offers to the world more than just LeBron James and Halle Berry. Unlike most other big cities, Cleveland still retains its quaint small-town feel, especially as you wander around the Cleveland Metroparks, a system of 21,000 acres of pure nature. For nature lovers, the Cleveland Botanical Garden provides a treasure trove of botanical knowledge and rare plant species. Another must-not-miss spot is the Rock & Roll Hall of Fame, which features exhibitions on the greatest legends such as Jimi Hendrix, The Beatles, etc.
For foodies, Cleveland truly is a mecca. The city boasts an array of top chefs and high-class establishments that can bring you an unforgettable experience. For authentic American classics, Sylman’s Deli has everything you need. If you are looking for a more diverse option, head to Momocho for some mouth-watering Mexican indulgences.
Cleveland’s main bus station is located just behind the Playhouse Square Parking Garage in the Theater District. The local Amtrak train station is also located downtown not too far from the bus station. The principal airport in the city is the Cleveland Hopkins International Airport, which sits 9 miles southwest of Downtown and is located next to the Glenn Research Center.
Station Information
Where does the bus leave from in Cleveland?

Image credit: Eli Pousson
Link to image attributionMain departure station: Bus Terminal - 1465 Chester Ave
Cleveland’s Bus Terminal at 1465 Chester Ave opened in 1948 amid wide celebration for its unique Streamline Moderne design. The aerodynamic architectural style, typical of Greyhound’s stations in big cities across the country, landed this station in the US National Register of Historic Places. Although the station was opened for Greyhound service, today, the station also serves Barons Bus Lines, Miller Transportation, and Jefferson Lines. Vending machines and a snack bar in the station give you a chance to fuel up or take a short walk to one of several nearby cafés. The station sits in the heart of downtown Cleveland, and the Amtrak station is only 1 mile away.
All bus stations in Cleveland:
Bus Terminal - 1465 Chester Ave
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Cleveland arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
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- Bus Tickets
- United States
- Tennessee
- Knoxville
- Cleveland, OH to Knoxville, TN






