Cheap bus tickets from Philadelphia to Knoxville
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Philadelphia to Knoxville Bus Schedule
Bus from Philadelphia to Knoxville: Journey Information
There is one daily bus from Philadelphia to Knoxville. Traveling by bus from Philadelphia to Knoxville usually takes around 20 hours, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 551 mi (886 km) |
| Shortest duration | 20h 0m |
| Cheapest price | CHF 68.22 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

Price trends for buses from Philadelphia to Knoxville
Average bus ticket prices from Philadelphia to Knoxville by month
What bus companies travel from Philadelphia to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Philadelphia to Knoxville. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 20h 0m | CHF 121.76 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Philadelphia to Knoxville, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Philadelphia to Knoxville
The bus takes an average of 20 hours to cover the 551 miles from Philadelphia to Knoxville. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Saturday is usually the day when buses are busiest, as many travelers take the bus to enjoy the weekend in Knoxville. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
There is usually only one bus per day from Philadelphia to Knoxville. It leaves the station in Philadelphia at 10:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Philadelphia



We may feel a little bit more than just brotherly love for Philadelphia, a city steeped in history and culture. Where else can you channel your inner Rocky Balboa on his epic run, and later enjoy an authentic Philly cheesesteak as a reward?
Philadelphia’s affordability (especially compared to other East Coast cities) is just one of many reasons it is among Wanderu’s best destinations for college students. Another reason is how much there is to do! Early American history takes precedence at Independence Hall and the Liberty Bell, while museums abound on Benjamin Franklin Parkway, sometimes called the most artistic mile in the city. Head to Reading Terminal Market to fuel up for a night hitting the bars, clubs, and live music joints that line South Street.
Philadelphia is a major hub for both Greyhound and Amtrak, and its 30th Street Station is one of the busiest stations in the country. The plentitude of ground travel and the nearby Philadelphia International Airport make this exciting city very easily accessible, even on a budget.
Station Information
Where does the bus leave from in Philadelphia?
Main departure station: Philadelphia Bus Terminal
Most buses depart from the main station in Philadelphia.
All bus stations in Philadelphia:
Philadelphia Bus Terminal
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Philadelphia arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
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