Cheap bus tickets from Greenville, SC to Durham, NC
Find and compare the best ground travel options in one place.
Bus from Greenville, SC to Durham, NC: Journey Information
There are 6 intercity buses per day from Greenville, SC to Durham, NC. Traveling by bus from Greenville, SC to Durham, NC usually takes around 4 hours and 56 minutes, but the fastest Tornado Bus bus can make the trip in 4 hours and 28 minutes.
- Distance
- 212 mi (341 km)
- Shortest duration
- 4h 28m
- Cheapest price
- DKK 249.89
- Trips per day
- 5
- Most frequent service
- Wanda Coach
- Bus lines
- 4
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Greenville, SC to Durham, NC Bus Schedule

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Average score for buses from Greenville, SC to Durham, NC (Based on 1 ratings and reviews)
There are several bus options that can take you from Greenville, SC to Durham, NC:
- FlixBus US: 2 daily buses from DKK 250
- Greyhound: 2 daily buses from DKK 256
- Tornado Bus: 1 daily buses from DKK 1,020
- Wanda Coach: 3 daily buses from DKK 329
How much is a bus ticket from Greenville, SC to Durham, NC?
Bus tickets for a trip from Greenville, SC to Durham, NC cost DKK 326.28 on average. Tickets cheaper than DKK 326.28 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Greenville, SC to Durham, NC by travel date
If you're planning to travel by bus from Greenville, SC to Durham, NC in the next month, the average ticket price is expected to range from DKK 329 to DKK 349. The cheapest bus tickets available in the next few weeks are for trips departing on October 11, 2026. If you’re looking to travel to Durham, NC this week, bus tickets are available starting at DKK 329.
Average bus ticket prices from Greenville, SC to Durham, NC by month
Traveling from Greenville, SC to Durham, NC by bus will cost you about the same throughout the year. In general, bus ticket prices for this route are fairly consistent, so expect to pay around DKK 342 whenever you decide to travel.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 8 days in advance. This way, you can save up to DKK 59.68 on your bus ticket compared to booking last-minute.
What bus companies travel from Greenville, SC to Durham, NC?
There are 4 bus lines from Greenville, SC to Durham, NC available for you to search and compare on Wanderu. With 3 daily trips, Wanda Coach usually has the most buses running on any given day. Here are some time and price comparisons for all the available options:
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 2 | 4h 43m | DKK 317.44 |
| Greyhound | 2 | 6h 18m | DKK 370.10 |
| Tornado Bus | 1 | 4h 32m | DKK 1,019.83 |
| Wanda Coach | 3 | 4h 45m | DKK 328.98 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Greenville, SC to Durham, NC, and the average ticket for this route costs only DKK 317.44.






Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 2 bus trips from Greenville, SC to Durham, NC every day, with the average journey taking around 6 hours and 18 minutes to complete. Bus tickets for Greyhound trips to Durham, NC usually start from DKK 256.47.






Wanda Coach is one of the leading Chinatown bus carriers in the U.S. The company offers 3 daily bus trips to and from more than 70 cities across the East Coast and the Midwest. With bus ticket prices starting from DKK 328.98 and convenient pick-up and drop-off locations, Wanda Coach is one of the preferred bus carriers for passengers looking to travel between the Chinatown districts of Greenville, SC and Durham, NC.
Frequently asked questions about traveling by bus from Greenville, SC to Durham, NC
There are 6 scheduled buses that travel from Greenville, SC to Durham, NC every day, so you have a decent number of options to choose from. This includes 5 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip. Need more travel options? Consider taking the train from Greenville, SC to Durham, NC; ticket prices start at DKK 507.
Trips per day
6
Direct trips
5
The bus takes an average of 4 hours and 56 minutes to cover the 212 miles from Greenville, SC to Durham, NC. However, the fastest bus only takes 4 hours and 28 minutes. In other words, you'll have plenty of time to rest and relax on the road. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
212
Distance (km)
341
The first bus leaves at 3:15am and the last bus leaves at 9:35pm. To see the times for all buses from Greenville, SC to Durham, NC, enter your specific travel dates in the search bar.
Earliest bus
3:15am
Latest bus
9:35pm
Sunday tends to be the busiest day for buses, as many passengers take the bus to Durham, NC at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Tuesday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Tuesday ticket is the way to go.
Most crowded
Sunday
Least crowded
Tuesday
City Information
Greenville



As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
Durham



Durham is a little treasure cove for all fans of history and the United States’ heritage. The first and foremost thing you should try out is go on a hike on one of the city’s iconic trails. For a more traditional hiking experience, try the Eno River Trail. If you wish to enjoy a more unique experience, the American Tobacco Trail will be a better choice, as it follows the old CSX railroad. For those who want to explore the city’s rich history, check out the Stagville Plantation, which is now a museum dedicated to the city’s antebellum history, offering a unique historical perspective.
Durham’s food scene is vibrant and exciting. Fans of seafood will definitely be amazed at how fresh and delicious the seafood at Mateo Bar de Tapas is. If you wish to try out Italian eats with a twist, check out Devil’s Pizzeria & Restaurant.
The main bus station is the Transportation Center located at 515 W Pettigrew St in Downtown Durham. From there, you can take a bus to New York, Richmond, Washington D.C., and dozens of other destinations across the country. The main Amtrak train station in Durham is located around the corner from the bus stop at 601 W Main St. Durham is served by Amtrak’s Carolinian and Piedmont lines. The city’s air services are handled by the Raleigh-Durham International Airport, 12 miles southeast of the city.
Station Information
Where does the bus leave from in Greenville, SC?
Main departure station: 2890 Laurens Rd
Buses to Durham, NC leave from 3 stations in Greenville, SC.
All bus stations in Greenville, SC:
- 2890 Laurens Rd
- 1116 Woodruff Rd
- 2803 White Horse Rd
Where does the bus arrive in Durham, NC?
Main arrival station: 2724 Guess Rd
Buses arrive in Durham, NC at 3 stations, depending on which bus line you are traveling with.
All bus stations in Durham, NC:
- 2724 Guess Rd
- Durham Transportation Center - Bus Bay T
- 2000 Avondale
Need a return trip from Durham, NC to Greenville, SC?
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More buses from Greenville, SC
- Greenville, SC to Philadelphia, PA BusDKK 520+
- Greenville, SC to Washington DC BusDKK 612+
- Greenville, SC to Newark, NJ BusDKK 632+
- Greenville, SC to Dallas, TX BusDKK 711+
- Greenville, SC to Greensboro, NC BusDKK 316+
- Greenville, SC to Charlotte, NC BusDKK 243+
- Greenville, SC to Asheville, NC Bus
- Greenville, SC to New York, NY BusDKK 770+
- Greenville, SC to Baltimore, MD BusDKK 612+
- Greenville, SC to Orlando, FL BusDKK 533+
- Greenville, SC to Boston, MA BusDKK 724+
- Greenville, SC to Columbus, OH BusDKK 612+
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- Greenville, SC to Chicago, IL BusDKK 651+
- Greenville, SC to Charleston, SC Bus
- Greenville, SC to Miami, FL BusDKK 658+
Continue by bus from Durham, NC
- Durham to Atlanta BusDKK 342+
- Durham to New York BusDKK 533+
- Durham to Portland BusDKK 1,513+
- Durham to Winston-Salem BusDKK 151+
- Durham to Charlotte BusDKK 217+
- Durham, NC to Newark, DE BusDKK 401+
- Durham, NC to Newark, NJ BusDKK 533+
- Durham to Raleigh BusDKK 132+
- Durham, NC to Washington DC BusDKK 454+
- Durham to Greensboro BusDKK 145+
- Durham to Columbia BusDKK 388+
- Durham to Baltimore BusDKK 526+
- Durham to Richmond BusDKK 408+
- Durham, NC to Greenville, SC BusDKK 303+

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