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Cheap bus tickets from Greenville, SC to Columbus, OH
Find and compare the best ground travel options in one place.
Bus from Greenville, SC to Columbus, OH: Journey Information
There are 5 intercity buses per day from Greenville, SC to Columbus, OH. Traveling by bus from Greenville, SC to Columbus, OH usually takes around 22 hours and 35 minutes, but the fastest FlixBus US bus can make the trip in 15 hours and 20 minutes.
- Distance
- 355 mi (571 km)
- Shortest duration
- 15h 20m
- Cheapest price
- NOK 754.78
- Trips per day
- 0
- Most frequent service
- Greyhound
- Bus lines
- 2
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Greenville, SC to Columbus, OH Bus Schedule
There are several bus options that can take you from Greenville, SC to Columbus, OH:
See more detailsHow much is a bus ticket from Greenville, SC to Columbus, OH?
Bus tickets for a trip from Greenville, SC to Columbus, OH cost NOK 895.28 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Greenville, SC to Columbus, OH by travel date
If you're planning to travel by bus from Greenville, SC to Columbus, OH in the next month, the average ticket price is expected to range from NOK 893 to NOK 1,169. The cheapest bus tickets available in the next few weeks are for trips departing on October 12, 2026. If you’re looking to travel to Columbus, OH this week, bus tickets are available starting at NOK 912.
Average bus ticket prices from Greenville, SC to Columbus, OH by month
Taking the bus from Greenville, SC to Columbus, OH is usually cheapest in October, when the average ticket price is only NOK 903. If you're planning to take the bus from Greenville, SC to Columbus, OH during March, keep in mind that bus ticket prices may be higher than usual, with an average price of NOK 1,473. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 9 days in advance. This way, you can save up to NOK 896.14 on your bus ticket compared to booking last-minute.
What bus companies travel from Greenville, SC to Columbus, OH?
There are two bus lines that have daily service from Greenville, SC to Columbus, OH that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 4 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 2 | 20h 27m | NOK 1,346.57 |
| Greyhound | 4 | 22h 50m | NOK 1,157.10 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Greenville, SC to Columbus, OH, and the average ticket for this route costs only NOK 1,346.57.
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 4 bus trips from Greenville, SC to Columbus, OH every day, with the average journey taking around 22 hours and 50 minutes to complete. Bus tickets for Greyhound trips to Columbus, OH usually start from NOK 754.78.
Frequently asked questions about traveling by bus from Greenville, SC to Columbus, OH
There are 5 scheduled buses that travel from Greenville, SC to Columbus, OH every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey.
Trips per day
5
Direct trips
0
The bus takes an average of 22 hours and 35 minutes to cover the 355 miles from Greenville, SC to Columbus, OH. However, the fastest bus only takes 15 hours and 20 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
355
Distance (km)
571
The first bus leaves at 3:15am and the last bus leaves at 9:35pm. To see the times for all buses from Greenville, SC to Columbus, OH, enter your specific travel dates in the search bar.
Earliest bus
3:15am
Latest bus
9:35pm
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
Most crowded
Thursday
Least crowded
Monday
City Information
Greenville
As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
Columbus
Brimming with life and cultural events, Columbus is the affordable destination of your dreams! Featuring a budding art scene, Columbus attracts art lovers through the exhibitions at the Columbus Museum of Arts where children and adults alike can indulge in thought-provoking artworks. Fans of sports should not miss out on a baseball game at Huntington Park, which offers reasonably-priced tickets; it is also rarely crowded. For those who simply want to stroll about, the German Village offers a quaint and scenic view rarely seen elsewhere.
As the sun goes down, dig deeper into the German heritage of Columbus by enjoying a traditional schnitzel dish at the Schmidt's Restaurant and Sausage Haus. When you are looking for a quick snack, Bodega serves some of the best sandwiches in town, and there are up to 47 varieties of craft beers for you to choose from.
Columbus’ busiest bus station is located on E Town St., and it offers intercity bus trips to Cleveland, Chicago, New York and many other cities. The Columbus Union Station was the first union station ever built, and it’s served by Amtrak’s Lake Shore Limited and Capitol Limited train lines. The local airport, the John Glenn Columbus International Airport, is located on the east side of the city, 6 miles east of Downtown. It provides access to 31 other airports.
Station Information
Where does the bus leave from in Greenville, SC?
Main departure station: 1116 Woodruff Rd
Most buses depart from the main station in Greenville, SC.
All bus stations in Greenville, SC:
- 1116 Woodruff Rd
Where does the bus arrive in Columbus, OH?
Main arrival station: Columbus (E Mound St)
These are the two stations where buses may stop when they arrive in Columbus, OH.
All bus stations in Columbus, OH:
- Columbus (E Mound St)
- 100 E Rich St
Need a return trip from Columbus, OH to Greenville, SC?
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