4.0
Pros: It went smoothly. Cons: Keeping to the time.
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There is one daily bus from Knoxville to Washington DC. Traveling by bus from Knoxville to Washington DC usually takes around 11 hours and 30 minutes, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 429 mi (690 km) |
| Shortest duration | 11h 30m |
| Cheapest price | RON 312.14 |
| Trips per day | 1 |
| Most frequent service | Greyhound |
| Bus lines | 1 |

Average score for buses from Knoxville to Washington
(Based on 1 ratings and reviews)
4.0
Pros: It went smoothly. Cons: Keeping to the time.
There is one intercity bus company available to search and book on Wanderu that operates from Knoxville to Washington DC. Greyhound is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 1 | 11h 30m | RON 400.48 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 1 bus trips from Knoxville to Washington every day, with the average journey taking around 11 hours and 30 minutes to complete. Bus tickets for Greyhound trips to Washington usually start from RON 303.
The bus takes an average of 11 hours and 30 minutes to cover the 429 miles from Knoxville to Washington DC. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Friday is the busiest travel day for buses as people head from Knoxville to Washington DC for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Saturday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Saturday ticket is the way to go.
There is usually only one bus per day from Knoxville to Washington DC. It leaves the station in Knoxville at 10:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.



Washington, DC is the capital of the United States, and as such, it offers many points of interest of governmental and historical value. DC is home to several iconic landmarks, including the White House where the U.S. president resides, the Capitol building that houses the meeting chambers of the Senate and the House of Representatives, and the National Mall, where you can stop by the Lincoln Memorial, the Washington Monument, and the World War II Memorial. One of the reasons Washington, DC is among the best destinations to visit with your family is because it is home to so many world-famous museums, including the Smithsonians – 16 museums scattered across the District, most of which are open every day of the week, and even better, every single one is free.
D.C. is not just about politics and museums, though. The city’s active nightlife fittingly ranks it among the biggest party hubs in the country. Head to the vibrant Dupont Circle neighborhood to check out some of the finest restaurants that the nation’s capital has to offer, or join a food tour of Georgetown to get a taste of the area’s culture along with its cuisine.
Nested between Virginia and Maryland, Washington, D.C. is a key transportation hub with three nearby airports and several bus and train stations.
Most buses depart from the main station in Knoxville.
Knoxville Bus Station

Opened more than 100 years ago in 1907, Union Station is the largest transportation hub in Washington, D.C. with almost 5 million travelers passing through it every year. As the official headquarters of Amtrak, Union Station is the main train station in the U.S. capital. It is also a major hub for intercity bus travel, serving as the main bus station in D.C. for a number of carriers, including Greyhound, BoltBus, Peter Pan Bus Lines and OurBus. Union Station offers easy transit connections to places all over D.C. with dedicated stops for the city’s metro, bus and streetcar services, as well as commuter rail for travelers to and from the surrounding areas. Additionally, with a full blown shopping mall on the premises, Union Station is also among the most popular shopping destinations in the nation's capital.
Union Station
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With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.