Cheap bus tickets from Knoxville to Philadelphia
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Knoxville to Philadelphia Bus Schedule
Bus from Knoxville to Philadelphia: Journey Information
There are 7 intercity buses per day from Knoxville to Philadelphia. Traveling by bus from Knoxville to Philadelphia usually takes around 22 hours and 38 minutes, but the fastest Greyhound bus can make the trip in 17 hours and 40 minutes.
| Distance | 551 mi (886 km) |
| Shortest duration | 17h 40m |
| Cheapest price | DKK 645.27 |
| Most frequent service | Greyhound |
| Bus lines | 1 |

What bus companies travel from Knoxville to Philadelphia?
There is one intercity bus company available to search and book on Wanderu that operates from Knoxville to Philadelphia. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 7 | 22h 38m | DKK 661.49 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 7 bus trips from Knoxville to Philadelphia every day, with the average journey taking around 22 hours and 38 minutes to complete. Bus tickets for Greyhound trips to Philadelphia usually start from DKK 645.
Frequently asked questions about traveling by bus from Knoxville to Philadelphia
The bus takes an average of 22 hours and 38 minutes to cover the 551 miles from Knoxville to Philadelphia. However, the fastest bus only takes 17 hours and 40 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
The first bus leaves at 3:00am and the last bus leaves at 11:00pm. To see the times for all buses from Knoxville to Philadelphia, enter your specific travel dates in the search bar.
City Information
Philadelphia



We may feel a little bit more than just brotherly love for Philadelphia, a city steeped in history and culture. Where else can you channel your inner Rocky Balboa on his epic run, and later enjoy an authentic Philly cheesesteak as a reward?
Philadelphia’s affordability (especially compared to other East Coast cities) is just one of many reasons it is among Wanderu’s best destinations for college students. Another reason is how much there is to do! Early American history takes precedence at Independence Hall and the Liberty Bell, while museums abound on Benjamin Franklin Parkway, sometimes called the most artistic mile in the city. Head to Reading Terminal Market to fuel up for a night hitting the bars, clubs, and live music joints that line South Street.
Philadelphia is a major hub for both Greyhound and Amtrak, and its 30th Street Station is one of the busiest stations in the country. The plentitude of ground travel and the nearby Philadelphia International Airport make this exciting city very easily accessible, even on a budget.
Station Information
Where does the bus leave from in Knoxville?
Main departure station: Knoxville Bus Station
Most buses depart from the main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
Where does the bus arrive in Philadelphia?
Main arrival station: 199 Spring Garden St
Buses arrive in Philadelphia at 3 stations, depending on which bus line you are traveling with.
All bus stations in Philadelphia:
199 Spring Garden St
199 Spring Garden St
Logan Square
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Need a return trip from Philadelphia to Knoxville?
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