Cheap bus tickets from Chicago to Louisville
Find and compare the best ground travel options in one place.
Bus from Chicago to Louisville: Journey Information
There are 19 intercity buses per day from Chicago to Louisville. Travelling by bus from Chicago to Louisville usually takes around 7 hours and 12 minutes, but the fastest FlixBus US bus can make the trip in 5 hours and 40 minutes.
- Distance
- 269 mi (433 km)
- Shortest duration
- 5h 40m
- Cheapest price
- CHF 30.88
- Trips per day
- 19
- Most frequent service
- Greyhound
- Bus lines
- 4
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Chicago to Louisville Bus Schedule

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Average score for buses from Chicago to Louisville (Based on 10 ratings and reviews)
5.0
5.0
4.0
4.0
There are several bus options that can take you from Chicago to Louisville:
- Amtrak Thruway: 2 daily buses from CHF 68
- Barons Bus Lines: 1 daily bus from CHF 116
- FlixBus US: 4 daily buses from CHF 33
- Greyhound: 13 daily buses from CHF 30
How much is a bus ticket from Chicago to Louisville?
Bus tickets for a trip from Chicago to Louisville cost about CHF 50 when you book at the cheapest time, 8 days ahead. Tickets cheaper than CHF 50 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Chicago to Louisville by travel date
If you're planning to travel by bus from Chicago to Louisville in the next month, the average ticket price is expected to range from CHF 48 to CHF 94. The cheapest bus tickets available in the next few weeks are for trips departing on December 7, 2026. If you’re looking to travel to Louisville this week, bus tickets are available starting at CHF 48.
Average bus ticket prices from Chicago to Louisville by month
Taking the bus from Chicago to Louisville is usually cheapest in September, when the average ticket price is only CHF 52. If you're planning to take the bus from Chicago to Louisville during June, keep in mind that bus ticket prices may be higher than usual, with an average price of CHF 62. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 8 days in advance. This way, you can save up to CHF 21.16 on your bus ticket compared to booking last-minute.
What bus companies travel from Chicago to Louisville?
There are 4 bus lines from Chicago to Louisville available for you to search and compare on Wanderu. With 13 daily trips, Greyhound usually has the most buses running on any given day. Here are some time and price comparisons for all the available options:
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Amtrak Thruway | 2 | 6h 46m | CHF 68.48 |
| Barons Bus Lines | 1 | 13h 55m | CHF 116.09 |
| FlixBus US | 4 | 7h 7m | CHF 54.71 |
| Greyhound | 13 | 6h 51m | CHF 52.16 |
Amtrak Thruway, also known as Amtrak Thruway Motorcoach, is a system of intercity passenger buses operated by Amtrak to connect train stations to areas that are not served by the carrier’s railways. On the bus, passengers can enjoy comfortable reclining seats with leg rests and access to onboard washroom facilities. Amtrak Thruway bus tickets from Chicago to Louisville start at CHF 68.48. On average, there are 2 Amtrak Thruway bus trips on this route every day.
Barons Bus Lines is a ground transportation company that serves various cities across the Midwest. The company follows through on its slogan of “ride like royalty” with a fleet of modern coaches boasting enhanced amenities such as free Wi-Fi, power outlets, ADA accessible steps, and spacious bathrooms. With a reputation for skilled drivers, top-notch safety, and stellar customer service, it's no wonder Barons Bus won the 2022 Wanderu Passengers' Choice Award for #1 Business Travellers' Favourite.
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 4 trips per day from Chicago to Louisville, and the average ticket for this route costs only CHF 54.71.






Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 13 bus trips from Chicago to Louisville every day, with the average journey taking around 6 hours and 51 minutes to complete. Bus tickets for Greyhound trips to Louisville usually start from CHF 30.05.






Frequently asked questions about travelling by bus from Chicago to Louisville
There are 19 scheduled buses that travel from Chicago to Louisville every day, so you have a decent number of options to choose from. This includes 14 direct buses, where you can stay on the same bus without having to transfer to a connecting bus at any point during your trip. Need more travel options? Consider taking the train from Chicago to Louisville; ticket prices start at CHF 67.
Trips per day
19
Direct trips
14
The bus takes an average of 7 hours and 12 minutes to cover the 433 kilometres from Chicago to Louisville. However, the fastest bus only takes 5 hours and 40 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
269
Distance (km)
433
The first bus leaves at 4:45 a.m. and the last bus leaves at 11:55 p.m. To see the times for all buses from Chicago to Louisville, enter your specific travel dates in the search bar.
Earliest bus
4:45am
Latest bus
11:55pm
Sunday tends to be the busiest day for buses, as many passengers take the bus to Louisville at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, travelling mid-week is your best bet.
Most crowded
Sunday
Least crowded
Wednesday
City Information
Chicago



Known for its innovative architecture, cultural contributions to jazz and house music, and of course that irresistible deep-dish pizza, the many sights and experiences in Chicago make it one of the best urban vacation destinations for millennials and a top destination in Illinois.
You can't beat the views of the city and Lake Michigan from the SkyDeck in the Willis Tower; at over 1,300 feet, this is the highest observation deck in the U.S. Snap that classic selfie with the Bean in Millennium Park, then wander the many museums in nearby Grant Park. Navy Pier is a popular tourist hotspot for its parks, restaurants, and attractions right on Lake Michigan, and baseball fans will find paradise in Wrigleyville, home to the Chicago Cubs' Wrigley Field and sports bars galore.
Chicago's enormous parks offer plentiful opportunities for outdoor activities in gorgeous urban settings. Many companies offer kayak rentals or boat tours on the Chicago River, with special tours running on Saint Patrick's Day, when the entire river is dyed green. When you’re ready to buy some souvenirs from your epic trip, hit the big brand stores on the Magnificent Mile, or shop local in neighbourhoods like Andersonville and Wicker Park. And don't miss the chance to laugh until you cry at The Second City comedy theatre, famous for launching the careers of comedians like Tina Fey and Stephen Colbert.
Chicago is one of the biggest transportation hubs in the Midwest, and provides easy access to nearby destinations ideal for day trips, as well as international travel from two airports. Thanks to plenty of bus and train stations throughout the city, getting to the Windy City is a breeze.
Louisville



A mecca for fans of sports, Louisville holds the honour of being the birthplace of many sports legends. Even non-sports fans should not miss out on the Muhammad Ali Center, where tourists can learn more about the life and legacy of the legendary boxer. Aside from permanent galleries dedicated to the boxer himself, the museum also features temporary exhibitions on topics such as race and gender equality. Another top highlight from the city is Churchill Downs, where the famous Kentucky Derby is hosted. Contrary to what people might imagine, the racing track is actually quite idyllic, and if there is one place you must visit in Louisville, this is probably the one. If you are looking for a unique experience, head towards the Louisville Mega Cavern. This cavern system was created out of a 19th-century limestone quarry and it features the world’s only underground zip line course.
Three things dominate the food scene in Louisville: barbecue, bourbon, and mint juleps. Some local favourites are Mark’s Feed Store and Feast BBQ. If you are looking for the finest bourbon, the Evan Williams Bourbon Experience is certainly a good call.
The central bus station in Louisville is the Bus Terminal on W Muhammad Ali Blvd, connecting the city with near and far destinations such as Cincinnati, Chicago and Nashville. There are no train tracks that run through the city. However, the city is still a part of Amtrak’s network via the carrier’s Thruway bus line. The Louisville International Airport fulfills air services for the city.
Station Information
Where does the bus leave from in Chicago?
Main departure station: Bus Station - 630 W Harrison St

Buses to Louisville leave from 4 stations in Chicago.
All bus stations in Chicago:
- Bus Station - 630 W Harrison St
- Dan Ryan Bus Station
- Chicago Train Station Bus Stop
- Union Station
Where does the bus arrive in Louisville?
Main arrival station: Louisville Bus Station
The Louisville Bus Terminal, located at 720 W Muhammad Ali Blvd, serves interstate Greyhound bus services. The station is equipped with washrooms, vending machines, and indoor seating. The station also has an adjoining cafeteria in case vending machine snacks aren't enough to satisfy your hunger. In addition, there is also a customer service and ticket kiosk where station staff can answer any questions you may have. The station is located in Downtown Louisville, only a short walk from the city's most exciting amenities and several nearby restaurants and convenience stores.
All bus stations in Louisville:
- Louisville Bus Station
Need a return trip from Louisville to Chicago?
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