Cheap bus tickets from Louisville to St Louis
Find and compare the best ground travel options in one place.
Bus from Louisville to St Louis: Journey Information
There are 3 intercity buses per day from Louisville to St Louis. Travelling by bus from Louisville to St Louis usually takes around 9 hours and 10 minutes, but the fastest Greyhound bus can make the trip in 7 hours and 35 minutes.
- Distance
- 242 mi (389 km)
- Shortest duration
- 7h 35m
- Cheapest price
- CHF 43.82
- Trips per day
- 3
- Most frequent service
- Greyhound
- Bus lines
- 1
Millions of travellers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 400+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travellers are saying about Wanderu:
Louisville to St Louis Bus Schedule

There are several bus options that can take you from Louisville to St Louis:
See more detailsHow much is a bus ticket from Louisville to St Louis?
Bus tickets for a trip from Louisville to St Louis cost about CHF 48 when you book at the cheapest time, 24 days ahead. Tickets cheaper than CHF 48 are an excellent bargain. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Louisville to St Louis by travel date
If you're planning to travel by bus from Louisville to St Louis in the next month, the average ticket price is expected to range from CHF 48 to CHF 72. The cheapest bus tickets available in the next few weeks are for trips departing on December 11, 2026. If you’re looking to travel to St Louis this week, bus tickets are available starting at CHF 52.
Average bus ticket prices from Louisville to St Louis by month
Taking the bus from Louisville to St Louis is usually cheapest in October, when the average ticket price is only CHF 54. If you're planning to take the bus from Louisville to St Louis during June, keep in mind that bus ticket prices may be higher than usual, with an average price of CHF 71. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 24 days in advance. This way, you can save up to CHF 39.24 on your bus ticket compared to booking last-minute.
What bus companies travel from Louisville to St Louis?
There is one intercity bus company available to search and book on Wanderu that operates from Louisville to St Louis. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 3 | 9h 10m | CHF 62.91 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 3 bus trips from Louisville to St Louis every day, with the average journey taking around 9 hours and 10 minutes to complete. Bus tickets for Greyhound trips to St Louis usually start from CHF 43.82.






Frequently asked questions about travelling by bus from Louisville to St Louis
There are 3 scheduled buses that travel from Louisville to St Louis every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey. Need more travel options? Consider taking the train from Louisville to St Louis; ticket prices start at CHF 94.
Trips per day
3
Direct trips
0
The bus takes an average of 9 hours and 10 minutes to cover the 389 kilometres from Louisville to St Louis. However, the fastest bus only takes 7 hours and 35 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
242
Distance (km)
389
The first bus leaves at 7:35 a.m. and the last bus leaves at 10:55 p.m. To see the times for all buses from Louisville to St Louis, enter your specific travel dates in the search bar.
Earliest bus
7:35am
Latest bus
10:55pm
With many people travelling in the middle of the week, Wednesday is the busiest day of the week for bus travel. If you are planning to travel on a Wednesday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Monday is typically the least busy day for bus travel on this route. For a less crowded trip, try to book your bus travel for the beginning of the week.
Most crowded
Wednesday
Least crowded
Monday
City Information
Louisville



A mecca for fans of sports, Louisville holds the honour of being the birthplace of many sports legends. Even non-sports fans should not miss out on the Muhammad Ali Center, where tourists can learn more about the life and legacy of the legendary boxer. Aside from permanent galleries dedicated to the boxer himself, the museum also features temporary exhibitions on topics such as race and gender equality. Another top highlight from the city is Churchill Downs, where the famous Kentucky Derby is hosted. Contrary to what people might imagine, the racing track is actually quite idyllic, and if there is one place you must visit in Louisville, this is probably the one. If you are looking for a unique experience, head towards the Louisville Mega Cavern. This cavern system was created out of a 19th-century limestone quarry and it features the world’s only underground zip line course.
Three things dominate the food scene in Louisville: barbecue, bourbon, and mint juleps. Some local favourites are Mark’s Feed Store and Feast BBQ. If you are looking for the finest bourbon, the Evan Williams Bourbon Experience is certainly a good call.
The central bus station in Louisville is the Bus Terminal on W Muhammad Ali Blvd, connecting the city with near and far destinations such as Cincinnati, Chicago and Nashville. There are no train tracks that run through the city. However, the city is still a part of Amtrak’s network via the carrier’s Thruway bus line. The Louisville International Airport fulfills air services for the city.
St Louis



St. Louis is one of several major cities in the state of Missouri and it is uniquely located near the confluence of the Mississippi and Missouri rivers. The city is usually recognized by its most distinctive feature, the Gateway Arch, thanks to which it is the only city in the United States that has a national park in the heart of its downtown district. The Arch is a must-see attraction and you can even take a tram to the top for some incredible views of the St. Louis skyline.
Some of the other truly unique attractions you can visit while you’re in town include the Miniature Museum of Greater St. Louis where you can check out an incredible collection of dolls, dollhouses and vignettes, and the City Museum where you can ride down a 10-story spiral slide (yup, you read that right.) For a great outdoor experience, stop by the gorgeous Missouri Botanical Garden, and then take a stroll through Citygarden where you will find various quirky statues and installations worthy of being featured in your Instagram feed.
Ale enthusiasts would be excited to know that St. Louis is one of the best craft beer cities in the U.S. as well as one of the cheapest drinking cities. That means your party budget could take you a long way. Unsurprisingly, the city is also among the best spring break destinations on a budget.
The main bus and train station in St. Louis, Gateway Station, is located right in the centre of downtown, not far from the Gateway Arch, which makes coming in and out of the city a breeze.
Station Information
Where does the bus leave from in Louisville?
Main departure station: Louisville Bus Station
The Louisville Bus Terminal, located at 720 W Muhammad Ali Blvd, serves interstate Greyhound bus services. The station is equipped with washrooms, vending machines, and indoor seating. The station also has an adjoining cafeteria in case vending machine snacks aren't enough to satisfy your hunger. In addition, there is also a customer service and ticket kiosk where station staff can answer any questions you may have. The station is located in Downtown Louisville, only a short walk from the city's most exciting amenities and several nearby restaurants and convenience stores.
All bus stations in Louisville:
- Louisville Bus Station
Where does the bus arrive in St Louis?
Main arrival station: Gateway Station - 430 S 15th St
All buses from Louisville arrive at one main station in St Louis.
All bus stations in St Louis:
- Gateway Station - 430 S 15th St
Need a return trip from St Louis to Louisville?
Search Bus TicketsPlan your next adventure
More buses from Louisville
- Louisville, KY to Washington DC BusCHF 83+
- Louisville to Chicago BusCHF 54+
- Louisville to Lexington Bus
- Louisville to New York BusCHF 98+
- Louisville to Cleveland BusCHF 57+
- Louisville to Knoxville BusCHF 57+
- Louisville to Nashville BusCHF 26+
- Louisville to Atlanta BusCHF 42+
- Louisville to Indianapolis BusCHF 28+
- Louisville to Detroit BusCHF 46+
- Louisville to Cincinnati BusCHF 33+
- Louisville to Columbus BusCHF 38+
- Louisville to Memphis BusCHF 57+
- Louisville, KY to Richmond, VA BusCHF 96+
Continue by bus from St Louis
- St Louis to Orlando BusCHF 108+
- St Louis to Carbondale BusCHF 23+
- St Louis to Chicago BusCHF 48+
- St Louis to Paducah BusCHF 26+
- St Louis to Minneapolis BusCHF 87+
- St Louis to Kansas City BusCHF 44+
- St Louis to Raleigh BusCHF 95+
- St Louis to Oklahoma City BusCHF 59+
- St Louis to Nashville BusCHF 38+
- St Louis to Atlanta BusCHF 56+
- St Louis to Champaign BusCHF 24+
- St Louis to Indianapolis BusCHF 33+
- St Louis to Boston BusCHF 123+
- St Louis to Columbia BusCHF 19+
- St Louis to Rolla Bus
- St Louis to Columbus BusCHF 38+
- St Louis to Memphis BusCHF 33+
- St Louis to Dallas BusCHF 89+
Check out these popular routes
- Calgary to Edmonton BusCHF 23+
- Vancouver to Seattle BusCHF 36+
- Washington DC to New York, NY BusCHF 33+
- Boston to New York BusCHF 40+
- Brooklyn to Philadelphia Bus
- New York, NY to Washington DC BusCHF 38+
- New York to Ithaca BusCHF 45+
- New York to Providence BusCHF 34+
- Providence to New York BusCHF 34+
- Edmonton to Calgary BusCHF 21+
- Montreal to New York BusCHF 77+
- Boston to Portland BusCHF 24+
- Portland, ME to Boston, MA BusCHF 24+
- Ithaca to New York BusCHF 46+
- New York to Boston BusCHF 42+
- New York to Philadelphia BusCHF 27+
- Philadelphia to New York BusCHF 24+
- Seattle to Vancouver BusCHF 35+

Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.




