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Cheap bus tickets from Orlando, FL to Greenville, SC
Find and compare the best ground travel options in one place.
Bus from Orlando, FL to Greenville, SC: Journey Information
There are 6 intercity buses per day from Orlando, FL to Greenville, SC. Traveling by bus from Orlando, FL to Greenville, SC usually takes around 12 hours and 53 minutes, but the fastest FlixBus US bus can make the trip in 10 hours and 10 minutes.
- Distance
- 440 mi (709 km)
- Shortest duration
- 10h 10m
- Cheapest price
- TRY 3,927.00
- Trips per day
- 0
- Most frequent service
- FlixBus US
- Bus lines
- 2
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Orlando, FL to Greenville, SC Bus Schedule
There are several bus options that can take you from Orlando, FL to Greenville, SC:
See more detailsHow much is a bus ticket from Orlando, FL to Greenville, SC?
Bus tickets for a trip from Orlando, FL to Greenville, SC cost TRY 4,195.40 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Orlando, FL to Greenville, SC by travel date
If you're planning to travel by bus from Orlando, FL to Greenville, SC in the next month, the average ticket price is expected to range from TRY 3,855 to TRY 7,711. The cheapest bus tickets available in the next few weeks are for trips departing on October 6, 2026. If you’re looking to travel to Greenville, SC this week, bus tickets are available starting at TRY 4,002.
Average bus ticket prices from Orlando, FL to Greenville, SC by month
Taking the bus from Orlando, FL to Greenville, SC is usually cheapest in October, when the average ticket price is only TRY 4,880. If you're planning to take the bus from Orlando, FL to Greenville, SC during February, keep in mind that bus ticket prices may be higher than usual, with an average price of TRY 6,881. However, booking your trip in advance can help you score a ticket at a better price.
Prices as travel date approaches
Most bus companies charge higher ticket prices closer to the date of travel, so it’s a good idea to buy your bus tickets as early as possible. To find the cheapest bus tickets, book your trip at least 16 days in advance. This way, you can save up to TRY 4,140.26 on your bus ticket compared to booking last-minute.
What bus companies travel from Orlando, FL to Greenville, SC?
There are two bus lines that have daily service from Orlando, FL to Greenville, SC that you can compare and book on Wanderu. Of these two carriers, FlixBus US usually offers more choice, with 6 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 6 | 12h 25m | TRY 6,193.16 |
| Tornado Bus | 1 | 28h 24m | TRY 15,860.25 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 6 trips per day from Orlando, FL to Greenville, SC, and the average ticket for this route costs only TRY 6,193.16.
Frequently asked questions about traveling by bus from Orlando, FL to Greenville, SC
There are 6 scheduled buses that travel from Orlando, FL to Greenville, SC every day, so you have a decent number of options to choose from. Unfortunately, none of them are direct connections, so no matter which bus you take, you will have to transfer buses at least once during your journey. Need more travel options? Consider taking the train from Orlando, FL to Greenville, SC; ticket prices start at TRY 7,174.
Trips per day
6
Direct trips
0
The bus takes an average of 12 hours and 53 minutes to cover the 440 miles from Orlando, FL to Greenville, SC. However, the fastest bus only takes 10 hours and 10 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Distance (mi)
440
Distance (km)
709
The first bus leaves at 4:45am and the last bus leaves at 10:55pm. To see the times for all buses from Orlando, FL to Greenville, SC, enter your specific travel dates in the search bar.
Earliest bus
4:45am
Latest bus
10:55pm
Sunday tends to be the busiest day for buses, as many passengers take the bus to Greenville, SC at the end of the week. If you are planning to travel on a Sunday, you should make sure to book tickets well in advance as they may sell out. On the other hand, Thursday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Thursday ticket is the way to go.
Most crowded
Sunday
Least crowded
Thursday
City Information
Orlando
Orlando is the Theme Park Capital of the World, thanks to the high density of thrilling parks like Walt Disney World, Universal Studios, SeaWorld, LEGOLAND, Gatorland and more. It's no wonder we rated Orlando the #1 travel destination for families. Family vacation or not, if the highlight of your trip is picking out a wand at Ollivanders in the Wizarding World of Harry Potter or finally meeting Elsa in the Magic Kingdom, you know we won't judge.
Winter Park and Thornton Park – not more theme parks, we promise – are trendy neighborhoods where you can experience some of Orlando's world-class shopping, dining, and craft beer. You can also immerse yourself in some of Florida's unique wildlife at Orlando Wetlands Park, or the more central Lake Eola Park downtown. Orlando enjoys an average of 233 days of sunshine a year, so even though it's one of the cheapest cities to visit over Spring Break, you'll soak up that sweet, sweet sun almost any time of year.
Craving the ocean? Head a few hours outside Orlando for some of Florida's gorgeous beaches like New Smyrna Beach, Cocoa Beach, and the Canaveral National Seashore. Two large airports, as well as many bus and train companies with service in the area, mean that traveling from Orlando to other sunny Florida destinations and beyond is a breeze.
Greenville
As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
Station Information
Where does the bus leave from in Orlando, FL?
Main departure station: Orlando Bus Terminal
The Bus Terminal at 555 N John Young Pkwy is the primary Greyhound bus station in Orlando, where travelers can catch a bus to other destinations throughout Florida and beyond. The station is located under 3 miles from downtown Orlando and the nearest SunRail station. There is also a Lynx public bus stop which conveniently drops people off right at the Greyhound Bus Terminal. Open 24 hours a day, the bus station provides vending machines if you need a quick bite, and there are also several fast food options within a short walk to fuel up before your trip.
All bus stations in Orlando, FL:
- Bus Terminal - 555 N John Young Pkwy
- The Florida Mall
- Servi Florida Travel
Where does the bus arrive in Greenville, SC?
Main arrival station: 1116 Woodruff Rd
These are the two stations where buses may stop when they arrive in Greenville, SC.
All bus stations in Greenville, SC:
- 1116 Woodruff Rd
- 2803 White Horse Rd
Need a return trip from Greenville, SC to Orlando, FL?
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