Cheap bus tickets from Chicago to Greenville
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Chicago to Greenville Bus Schedule
Is it better to travel by bus or train from Chicago to Greenville?
There are usually 1 daily train trips available from Chicago to Greenville.
Bus | Train | |
|---|---|---|
Avg. Price | Avg. PriceHRK 1,137.88 | Avg. PriceHRK 2,271.91 |
Daily Trips | Daily Trips5 | Daily Trips1 |
Duration | Duration1d 1h 31m | Duration1d 9h 57m |
Bus from Chicago to Greenville: Journey Information
There are 7 intercity buses per day from Chicago to Greenville. Traveling by bus from Chicago to Greenville usually takes around 23 hours and 46 minutes, but the fastest FlixBus US bus can make the trip in 17 hours and 20 minutes.
| Distance | 562 mi (904 km) |
| Shortest duration | 17h 20m |
| Cheapest price | HRK 617.01 |
| Trips per day | 1 |
| Most frequent service | FlixBus US |
| Bus lines | 2 |

What bus companies travel from Chicago to Greenville?
There are two bus lines that have daily service from Chicago to Greenville that you can compare and book on Wanderu. Of these two carriers, FlixBus US usually offers more choice, with 7 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 7 | 22h 32m | HRK 1,100.98 |
| Tornado Bus | 1 | 1d 22h 8m | HRK 2,595.67 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 7 trips per day from Chicago to Greenville, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Chicago to Greenville
The bus takes an average of 23 hours and 46 minutes to cover the 562 miles from Chicago to Greenville. However, the fastest bus only takes 17 hours and 20 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Saturday is usually the day when buses are busiest, as many travelers take the bus to enjoy the weekend in Greenville. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
The first bus leaves at 12:00am and the last bus leaves at 11:00pm. To see the times for all buses from Chicago to Greenville, enter your specific travel dates in the search bar.
There are 7 scheduled buses that travel from Chicago to Greenville every day, so you have a decent number of options to choose from. However, only one of these is a direct bus. With direct service, you do not have to transfer onto a different bus at any point during your trip. Direct buses also tend to be significantly faster, which is worth bearing in mind as you compare the available options.
Need more travel options? Consider taking the train from Chicago, IL to Greenville, SC; ticket prices start at HRK 1,227.88.
City Information
Chicago



Known for its innovative architecture, cultural contributions to jazz and house music, and of course that irresistible deep-dish pizza, the many sights and experiences in Chicago make it one of the best urban vacation destinations for millennials and a top destination in Illinois.
You can't beat the views of the city and Lake Michigan from the SkyDeck in the Willis Tower; at over 1,300 feet, this is the highest observation deck in the U.S. Snap that classic selfie with the Bean in Millennium Park, then wander the many museums in nearby Grant Park. Navy Pier is a popular tourist hotspot for its parks, restaurants, and attractions right on Lake Michigan, and baseball fans will find paradise in Wrigleyville, home to the Chicago Cubs' Wrigley Field and sports bars galore.
Chicago's enormous parks offer plentiful opportunities for outdoor activities in gorgeous urban settings. Many companies offer kayak rentals or boat tours on the Chicago River, with special tours running on Saint Patrick's Day, when the entire river is dyed green. When you’re ready to buy some souvenirs from your epic trip, hit the big brand stores on the Magnificent Mile, or shop local in neighborhoods like Andersonville and Wicker Park. And don't miss the chance to laugh until you cry at The Second City comedy theater, famous for launching the careers of comedians like Tina Fey and Stephen Colbert.
Chicago is one of the biggest transportation hubs in the Midwest, and provides easy access to nearby destinations ideal for day trips, as well as international travel from two airports. Thanks to plenty of bus and train stations throughout the city, getting to the Windy City is a breeze.
Greenville

Image credit: Unsplash

Image credit: Unsplash

Image credit: Unsplash
As the sixth-largest city in the state of South Carolina, Greenville is one of the state's hidden treasures! The city is a vibrant hub of artistic activities and exhibitions, with many on display at the Greenville County Museum of Art. For fans of automobiles, especially BMW cars, the BMW Zentrum will offer a comprehensive look at the brand's past, present, and future. To get close to nature, check out Cedar Falls Park, which features a majestic 200-foot wide waterfall as well as plenty of other scenic spots.
The city of Greenville boasts a vibrant food scene with plenty of signature Southern dishes. One of the best places in town to enjoy an authentic Southern BBQ dinner is at Bacon Bros. Public House, which offers impressive dishes at very affordable prices. For a more upscale dining experience, check out Passerelle Bistro, where you can have some of the finest French dishes.
Greenville is well-connected by both buses and trains, with frequent service to destinations like Orlando, New Orleans, Richmond, and even New York. Plus, the Greenville-Spartanburg International Airport is only 15 minutes from downtown Greenville.
Station Information
Where does the bus leave from in Chicago?
Main departure station: Dan Ryan Bus Station
Buses to Greenville leave from 3 stations in Chicago.
All bus stations in Chicago:
Dan Ryan Bus Station
Bus Station - 630 W Harrison St
3501 S California Ave
Where does the bus arrive in Greenville?
Main arrival station: 1116 Woodruff Rd
These are the two stations where buses may stop when they arrive in Greenville.
All bus stations in Greenville:
1116 Woodruff Rd
2803 White Horse Rd
Get around town with Moovit
Need a return trip from Greenville to Chicago?
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