Cheap bus tickets from Chicago to Knoxville
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Chicago to Knoxville Bus Schedule
Bus from Chicago to Knoxville: Journey Information
There are 6 intercity buses per day from Chicago to Knoxville. Traveling by bus from Chicago to Knoxville usually takes around 18 hours and 37 minutes, but the fastest Greyhound bus can make the trip in 15 hours and 30 minutes.
| Distance | 455 mi (732 km) |
| Shortest duration | 15h 30m |
| Cheapest price | HRK 600.97 |
| Most frequent service | Greyhound |
| Bus lines | 2 |
How much is a bus ticket from Chicago to Knoxville?
Bus tickets for a trip from Chicago to Knoxville cost HRK 653.54 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Monthly avg. prices
What bus companies travel from Chicago to Knoxville?
There are two bus lines that have daily service from Chicago to Knoxville that you can compare and book on Wanderu. Of these two carriers, Greyhound usually offers more choice, with 4 scheduled trips per day.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 2 | 19h 1m | HRK 1,113.17 |
| Greyhound | 4 | 18h 34m | HRK 1,065.40 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 2 trips per day from Chicago to Knoxville, and the average ticket for this route costs only .
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 4 bus trips from Chicago to Knoxville every day, with the average journey taking around 18 hours and 34 minutes to complete. Bus tickets for Greyhound trips to Knoxville usually start from HRK 594.
Frequently asked questions about traveling by bus from Chicago to Knoxville
The bus takes an average of 18 hours and 37 minutes to cover the 455 miles from Chicago to Knoxville. However, the fastest bus only takes 15 hours and 30 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Friday is the busiest travel day for buses as people head from Chicago to Knoxville for the weekend. If you are planning to travel on a Friday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Saturday is typically the least busy day for bus travel on this route. If you’re looking for a little extra space, a Saturday ticket is the way to go.
The first bus leaves at 12:00am and the last bus leaves at 11:00pm. To see the times for all buses from Chicago to Knoxville, enter your specific travel dates in the search bar.
City Information
Chicago
Known for its innovative architecture, cultural contributions to jazz and house music, and of course that irresistible deep-dish pizza, the many sights and experiences in Chicago make it one of the best urban vacation destinations for millennials and a top destination in Illinois.
You can't beat the views of the city and Lake Michigan from the SkyDeck in the Willis Tower; at over 1,300 feet, this is the highest observation deck in the U.S. Snap that classic selfie with the Bean in Millennium Park, then wander the many museums in nearby Grant Park. Navy Pier is a popular tourist hotspot for its parks, restaurants, and attractions right on Lake Michigan, and baseball fans will find paradise in Wrigleyville, home to the Chicago Cubs' Wrigley Field and sports bars galore.
Chicago's enormous parks offer plentiful opportunities for outdoor activities in gorgeous urban settings. Many companies offer kayak rentals or boat tours on the Chicago River, with special tours running on Saint Patrick's Day, when the entire river is dyed green. When you’re ready to buy some souvenirs from your epic trip, hit the big brand stores on the Magnificent Mile, or shop local in neighborhoods like Andersonville and Wicker Park. And don't miss the chance to laugh until you cry at The Second City comedy theater, famous for launching the careers of comedians like Tina Fey and Stephen Colbert.
Chicago is one of the biggest transportation hubs in the Midwest, and provides easy access to nearby destinations ideal for day trips, as well as international travel from two airports. Thanks to plenty of bus and train stations throughout the city, getting to the Windy City is a breeze.
Station Information
Where does the bus leave from in Chicago?
Main departure station: Dan Ryan Bus Station
Buses to Knoxville leave from 3 stations in Chicago.
All bus stations in Chicago:
Dan Ryan Bus Station
Bus Station - 630 W Harrison St
Chicago Train Station Bus Stop
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Chicago arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
Get around town with Moovit
Need a return trip from Knoxville to Chicago?
Search Bus TicketsPlan your next adventure
More buses from Chicago
- Chicago to Aguascalientes Bus
HRK 2,004+
- Chicago to Santiago Papasquiaro Bus
HRK 2,070+
- Bus from Chicago to Celaya
HRK 1,938+
- Chicago to Ciudad Hidalgo Bus
HRK 2,037+
- Chicago to Birmingham Bus
HRK 1,122+
- Bus from Chicago to Dubuque
HRK 238+
- Bus from Chicago to Fort Wayne
HRK 296+
- Chicago to Indianapolis
HRK 348+
- Chicago to Ann Arbor
HRK 375+
- Bus from Chicago to Detroit
HRK 349+
- Bus from Chicago to Flint
HRK 451+
- Bus from Chicago to Holland
HRK 311+
- Bus from Chicago to Traverse City
HRK 352+
- Chicago to Minneapolis Bus
HRK 619+
- Bus from Chicago to Newark
HRK 970+
- Chicago to Nashville
HRK 667+
- Bus from Chicago to Madison
HRK 250+
- Chicago to Milwaukee
HRK 227+
Continue by bus from Knoxville
- Chattanooga to Atlanta Bus
HRK 187+
- Bus from Chattanooga to Knoxville
HRK 183+
- Chattanooga to Nashville
HRK 176+
- Clarksville to Nashville
HRK 130+
- Johnson City to New York
HRK 789+
- Bus from Knoxville to Chicago
HRK 1,283+
- Knoxville to Indianapolis
HRK 855+
- Knoxville to Charlotte Bus
HRK 1,020+
- Knoxville to Chattanooga Bus
HRK 177+
- Bus from Knoxville to Memphis
HRK 976+
- Knoxville to Nashville Bus
HRK 330+
- Bus from Memphis to Atlanta
HRK 681+
- Memphis to Nashville
HRK 446+
- Bus from Murfreesboro to Atlanta
HRK 383+
- Bus from Murfreesboro to Nashville
HRK 68+
- Bus from Nashville to Atlanta
HRK 319+
- Bus from Nashville to Knoxville
HRK 352+
- Nashville to Memphis Bus
HRK 338+
Check out these popular routes
- Bus from Calgary to Edmonton
HRK 153+
- Bus from Vancouver to Seattle
HRK 365+
- Toronto to Ottawa Bus
HRK 178+
- Washington D.C. to New York Bus
HRK 99+
- Boston to New York
HRK 186+
- Brooklyn to Philadelphia
HRK 57+
- Ithaca to New York Bus
HRK 371+
- Bus from New York to Montreal
HRK 643+
- Bus from New York to Washington D.C.
HRK 164+
- Bus from New York to Atlanta
HRK 1,174+
- Bus from New York to Boston
HRK 185+
- New York to Ithaca Bus
HRK 300+
- Bus from New York to Philadelphia
HRK 127+
- Bus from New York to Providence
HRK 193+
- Philadelphia to Brooklyn Bus
HRK 99+
- Bus from Philadelphia to New York
HRK 130+
- Bus from Providence to New York
HRK 206+
- Madison to Chicago Bus
HRK 250+
Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.