Cheap bus tickets from Detroit to Knoxville
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Detroit to Knoxville Bus Schedule
Bus from Detroit to Knoxville: Journey Information
There are 4 intercity buses per day from Detroit to Knoxville. Traveling by bus from Detroit to Knoxville usually takes around 19 hours and 33 minutes, but the fastest Greyhound bus can make the trip in 12 hours and 15 minutes.
| Distance | 443 mi (712 km) |
| Shortest duration | 12h 15m |
| Cheapest price | PLN 238.75 |
| Trips per day | 1 |
| Most frequent service | Greyhound |
| Bus lines | 1 |

How much is a bus ticket from Detroit to Knoxville?
Bus tickets for a trip from Detroit to Knoxville cost PLN 316.80 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Detroit to Knoxville by month
Prices as travel date approaches
To save money on bus tickets, buy them as early as possible. Bus carriers usually charge higher ticket prices the closer you book to the date of travel. Book your ticket at least 21 days in advance to save up to PLN 244.10.
What bus companies travel from Detroit to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Detroit to Knoxville. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 4 | 19h 33m | PLN 431.68 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 4 bus trips from Detroit to Knoxville every day, with the average journey taking around 19 hours and 33 minutes to complete. Bus tickets for Greyhound trips to Knoxville usually start from PLN 239.
Frequently asked questions about traveling by bus from Detroit to Knoxville
The bus takes an average of 19 hours and 33 minutes to cover the 443 miles from Detroit to Knoxville. However, the fastest bus only takes 12 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Travelers prefer riding the bus on Saturday to enjoy the weekend in Knoxville. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
The first bus leaves at 6:00am and the last bus leaves at 11:00pm. To see the times for all buses from Detroit to Knoxville, enter your specific travel dates in the search bar.
City Information
Detroit



Often stigmatized as a dead city, Detroit is making a huge comeback, and it is fast becoming a hidden gem among travelers. Your first stop should be at the Detroit Institute of Art, the city’s foremost cultural destination. Featuring more than 100 galleries with artworks from masters such as Van Gogh or Diego Rivera, the museum offers tourists hours of artistic immersion and enjoyment. For those wishing to learn more about the history of Motown or Black American communities, the city’s Motown Museum and Charles H. Wright Museum of African American History will be top-tier destinations. Finally, don’t miss out on the chance to catch a performance at the lavish Fox Theater, a national landmark.
As Detroit is the birthplace of Coney dog, it would be a huge miss if you pass up the chance to try out this masterpiece. One of the locals’ favorite Coney dog establishments is Lafayette Coney Island. Detroit’s craft beer scene is also quite lively, and some famous local brands include Batch Brewing Company and Detroit Beer Co.
The principal bus terminal in the city is on Howard St, where travelers can catch buses run by Greyhound, Indian Trails or Barons Bus. You can also catch Amtrak trains at the train station in New Center, north of downtown Detroit. Detroit is served by Amtrak’s Wolverine line. The city’s main airport is the Detroit Metropolitan Wayne County Airport, which is located in nearby Romulus.
Station Information
Where does the bus leave from in Detroit?

Image credit: Dane
Link to image attributionMain departure station: Bus Terminal - 1001 Howard St
Located near hip Corktown, the Detroit Greyhound Bus Station is minutes away from local breweries, diverse restaurants, and a vibrant nightlife. Besides Greyhound, many other bus carriers serve this station, including Indian Trails, Barons Bus Lines, Miller Transportation, and Jefferson Lines. For travelers’ convenience, the station offers massive parking lots, clean restrooms, and lockers to rent. The station is a short walk from several local bus stops, and about a 15 minute walk from the closest light rail station to connect to neighborhoods throughout Detroit.
All bus stations in Detroit:
Bus Terminal - 1001 Howard St
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Detroit arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
Get around town with Moovit
Need a return trip from Knoxville to Detroit?
Search Bus TicketsPlan your next adventure
More buses from Detroit
- Bus from Detroit to Atlanta
PLN 446+
- Detroit to Chicago Bus
PLN 214+
- Bus from Detroit to South Bend
PLN 208+
- Detroit to Ann Arbor
PLN 43+
- Bus from Detroit to Cheboygan
PLN 195+
- Detroit to East Lansing
PLN 82+
- Detroit to Flint Bus
PLN 72+
- Detroit to Gaylord
PLN 182+
- Bus from Detroit to Grayling
PLN 164+
- Detroit to Kalamazoo
PLN 134+
- Bus from Detroit to Mt. Pleasant
PLN 124+
- Bus from Detroit to Petoskey
PLN 206+
- Detroit to Pontiac Bus
PLN 29+
- Detroit to Sault Ste. Marie Bus
PLN 245+
- Detroit to Buffalo Bus
PLN 355+
- Bus from Detroit to New York
PLN 582+
- Bus from Detroit to Cleveland
PLN 138+
- Detroit to Milwaukee Bus
PLN 302+
Continue by bus from Knoxville
- Chattanooga to Atlanta Bus
PLN 103+
- Bus from Chattanooga to Knoxville
PLN 101+
- Chattanooga to Nashville
PLN 97+
- Jackson to Nashville Bus
PLN 134+
- Johnson City to New York
PLN 362+
- Knoxville to Washington D.C. Bus
PLN 304+
- Bus from Knoxville to Chicago
PLN 590+
- Knoxville to Indianapolis
PLN 394+
- Knoxville to Charlotte Bus
PLN 424+
- Bus from Knoxville to New York
PLN 362+
- Knoxville to Chattanooga Bus
PLN 98+
- Knoxville to Nashville Bus
PLN 183+
- Bus from Memphis to Atlanta
PLN 328+
- Memphis to Nashville
PLN 220+
- Bus from Murfreesboro to Atlanta
PLN 182+
- Bus from Murfreesboro to Nashville
PLN 59+
- Bus from Nashville to Atlanta
PLN 178+
- Nashville to Memphis Bus
PLN 202+
Check out these popular routes
- Bus from Calgary to Edmonton
PLN 79+
- Bus from Edmonton to Calgary
PLN 78+
- Bus from Vancouver to Seattle
PLN 134+
- Toronto to Ottawa Bus
PLN 104+
- Montreal to New York Bus
PLN 305+
- Boston to New York
PLN 122+
- Brooklyn to Washington D.C. Bus
PLN 140+
- Bus from New York to Montreal
PLN 307+
- Bus from New York to Washington D.C.
PLN 108+
- Bus from New York to Atlanta
PLN 552+
- Bus from New York to Boston
PLN 138+
- Bus from New York to Philadelphia
PLN 67+
- Bus from New York to Providence
PLN 155+
- Bus from Philadelphia to New York
PLN 65+
- Bus from Providence to New York
PLN 149+
- Dallas to Houston Bus
PLN 147+
- Houston to Dallas Bus
PLN 132+
- Seattle to Vancouver Bus
PLN 134+

Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
- Bus Tickets
- United States
- Tennessee
- Knoxville
- Detroit to Knoxville






