Cheap bus tickets from Detroit to Knoxville
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Detroit to Knoxville Bus Schedule
Bus from Detroit to Knoxville: Journey Information
There are 5 intercity buses per day from Detroit to Knoxville. Traveling by bus from Detroit to Knoxville usually takes around 19 hours and 35 minutes, but the fastest Greyhound bus can make the trip in 12 hours and 15 minutes.
| Distance | 443 mi (712 km) |
| Shortest duration | 12h 15m |
| Cheapest price | RON 229.08 |
| Trips per day | 1 |
| Most frequent service | Greyhound |
| Bus lines | 1 |
How much is a bus ticket from Detroit to Knoxville?
Bus tickets for a trip from Detroit to Knoxville cost RON 320.87 on average. While it’s a bit pricey for a bus ticket, it’s still significantly more cost-effective than flying. If you book your trip ahead of time using Wanderu, you can easily find bus tickets at or below this price.
Average bus ticket prices from Detroit to Knoxville by travel date
Over the next four weeks, the average price of bus tickets from Detroit to Knoxville is expected to be between RON 335 and RON 564. The cheapest day to travel in the next month is November 13, 2025, when tickets are available for November 13, 2025. The cheapest bus tickets available in the next week start at just RON 335.
Average bus ticket prices from Detroit to Knoxville by month
Prices as travel date approaches
To save money on bus tickets, buy them as early as possible. Bus carriers usually charge higher ticket prices the closer you book to the date of travel. Book your ticket at least 11 days in advance to save up to RON 235.56.
What bus companies travel from Detroit to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Detroit to Knoxville. Greyhound connects the two cities by bus, it offers multiple scheduled buses per day for you to choose from.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| Greyhound | 5 | 19h 36m | RON 372.49 |
Greyhound is the largest nationwide bus carrier in the United States, offering cheap, safe and reliable service across the country. Greyhound has become a household name, serving over 16 million passengers per year with daily trips to over 2,400 destinations. Greyhound performs about 5 bus trips from Detroit to Knoxville every day, with the average journey taking around 19 hours and 36 minutes to complete. Bus tickets for Greyhound trips to Knoxville usually start from RON 229.
Frequently asked questions about traveling by bus from Detroit to Knoxville
The bus takes an average of 19 hours and 35 minutes to cover the 443 miles from Detroit to Knoxville. However, the fastest bus only takes 12 hours and 15 minutes. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Thursday is usually the day of the week when buses are busiest. If you are planning to travel on a Thursday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Sunday is typically the least busy day for bus travel on this route. If you are looking for less crowded buses to Knoxville, book your ticket for the last day of the week.
The first bus leaves at 6:00am and the last bus leaves at 11:00pm. To see the times for all buses from Detroit to Knoxville, enter your specific travel dates in the search bar.
City Information
Detroit
Often stigmatized as a dead city, Detroit is making a huge comeback, and it is fast becoming a hidden gem among travelers. Your first stop should be at the Detroit Institute of Art, the city’s foremost cultural destination. Featuring more than 100 galleries with artworks from masters such as Van Gogh or Diego Rivera, the museum offers tourists hours of artistic immersion and enjoyment. For those wishing to learn more about the history of Motown or Black American communities, the city’s Motown Museum and Charles H. Wright Museum of African American History will be top-tier destinations. Finally, don’t miss out on the chance to catch a performance at the lavish Fox Theater, a national landmark.
As Detroit is the birthplace of Coney dog, it would be a huge miss if you pass up the chance to try out this masterpiece. One of the locals’ favorite Coney dog establishments is Lafayette Coney Island. Detroit’s craft beer scene is also quite lively, and some famous local brands include Batch Brewing Company and Detroit Beer Co.
The principal bus terminal in the city is on Howard St, where travelers can catch buses run by Greyhound, Indian Trails or Barons Bus. You can also catch Amtrak trains at the train station in New Center, north of downtown Detroit. Detroit is served by Amtrak’s Wolverine line. The city’s main airport is the Detroit Metropolitan Wayne County Airport, which is located in nearby Romulus.
Station Information
Where does the bus leave from in Detroit?
Image credit: Dane
Link to image attributionMain departure station: Bus Terminal - 1001 Howard St
Located near hip Corktown, the Detroit Greyhound Bus Station is minutes away from local breweries, diverse restaurants, and a vibrant nightlife. Besides Greyhound, many other bus carriers serve this station, including Indian Trails, Barons Bus Lines, Miller Transportation, and Jefferson Lines. For travelers’ convenience, the station offers massive parking lots, clean restrooms, and lockers to rent. The station is a short walk from several local bus stops, and about a 15 minute walk from the closest light rail station to connect to neighborhoods throughout Detroit.
All bus stations in Detroit:
Bus Terminal - 1001 Howard St
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Detroit arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
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