Cheap bus tickets from Philadelphia to Knoxville
Find and compare the best ground travel options in one place.
Millions of travelers trust Wanderu every year to get:
Lowest Prices
We find the cheapest bus & train tickets, so you can wander for less.
Best Travel Options
We partner with 500+ carriers to bring you the most bus & train options.
Quick & Easy Booking
Book trips quickly with a simple, hassle-free checkout – online & on our app.
Fast Customer Support
We don’t monkey around. We respond within minutes to help you out.
See what travelers are saying about Wanderu:
Philadelphia to Knoxville Bus Schedule
Bus from Philadelphia to Knoxville: Journey Information
There is one daily bus from Philadelphia to Knoxville. Traveling by bus from Philadelphia to Knoxville usually takes around 20 hours, but some buses might arrive slightly earlier or later than scheduled depending on traffic conditions.
| Distance | 551 mi (886 km) |
| Shortest duration | 20h 0m |
| Cheapest price | PLN 318.43 |
| Most frequent service | FlixBus US |
| Bus lines | 1 |

Price trends for buses from Philadelphia to Knoxville
Average bus ticket prices from Philadelphia to Knoxville by month
What bus companies travel from Philadelphia to Knoxville?
There is one intercity bus company available to search and book on Wanderu that operates from Philadelphia to Knoxville. FlixBus US is the only company that has bus schedules available to search and book at the moment. It only makes the trip once a day on most days.
| Bus | Daily Trips | Avg. Time | Avg. Price |
|---|---|---|---|
| FlixBus US | 1 | 20h 0m | PLN 568.31 |
FlixBus US is the American branch of German bus company FlixBus, known for providing sustainable, affordable, and modern bus travel. The company offers cheap bus tickets to popular urban destinations throughout the United States. FlixBus US buses include many amenities, including comfortable seats, free WiFi, power outlets at every seat, and an online portal for free entertainment. On average, FlixBus US operates 1 trips per day from Philadelphia to Knoxville, and the average ticket for this route costs only .
Frequently asked questions about traveling by bus from Philadelphia to Knoxville
The bus takes an average of 20 hours to cover the 551 miles from Philadelphia to Knoxville. It’s definitely on the longer side, so plan to get comfortable for a long road trip. Keep in mind that your actual bus may arrive earlier or later than scheduled, depending on whether there is more or less traffic than usual.
Saturday is usually the day when buses are busiest, as many travelers take the bus to enjoy the weekend in Knoxville. If you are planning to travel on a Saturday, you should make sure to book tickets well in advance as they may sell out.
On the other hand, Wednesday is typically the least busy day for bus travel on this route. If you're looking for some extra space on the bus, traveling mid-week is your best bet.
There is usually only one bus per day from Philadelphia to Knoxville. It leaves the station in Philadelphia at 10:00pm each day. The time might vary for specific dates, so be sure to search on Wanderu for the most up-to-date information.
City Information
Philadelphia



We may feel a little bit more than just brotherly love for Philadelphia, a city steeped in history and culture. Where else can you channel your inner Rocky Balboa on his epic run, and later enjoy an authentic Philly cheesesteak as a reward?
Philadelphia’s affordability (especially compared to other East Coast cities) is just one of many reasons it is among Wanderu’s best destinations for college students. Another reason is how much there is to do! Early American history takes precedence at Independence Hall and the Liberty Bell, while museums abound on Benjamin Franklin Parkway, sometimes called the most artistic mile in the city. Head to Reading Terminal Market to fuel up for a night hitting the bars, clubs, and live music joints that line South Street.
Philadelphia is a major hub for both Greyhound and Amtrak, and its 30th Street Station is one of the busiest stations in the country. The plentitude of ground travel and the nearby Philadelphia International Airport make this exciting city very easily accessible, even on a budget.
Station Information
Where does the bus leave from in Philadelphia?
Main departure station: Philadelphia Bus Terminal
Most buses depart from the main station in Philadelphia.
All bus stations in Philadelphia:
Philadelphia Bus Terminal
Where does the bus arrive in Knoxville?
Main arrival station: Knoxville Bus Station
All buses from Philadelphia arrive at one main station in Knoxville.
All bus stations in Knoxville:
Knoxville Bus Station
Get around town with Moovit
Need a return trip from Knoxville to Philadelphia?
Search Bus TicketsPlan your next adventure
More buses from Philadelphia
- Bus from Philadelphia to Mexico City
PLN 1,556+
- Philadelphia to Washington D.C. Bus
PLN 62+
- Philadelphia to Savannah
PLN 721+
- Philadelphia to Boston Bus
PLN 252+
- Philadelphia to Springfield Bus
PLN 239+
- Philadelphia to Baltimore Bus
PLN 71+
- Bus from Philadelphia to College Park
PLN 127+
- Bus from Philadelphia to Bangor
PLN 416+
- Philadelphia to Minneapolis
PLN 812+
- Bus from Philadelphia to Portsmouth
PLN 398+
- Bus from Philadelphia to Newark
PLN 107+
- Philadelphia to Brooklyn Bus
PLN 56+
- Bus from Philadelphia to New York
PLN 68+
- Philadelphia to Syracuse
PLN 325+
- Philadelphia to York Bus
PLN 163+
- Bus from Philadelphia to Charlottesville
PLN 317+
- Bus from Philadelphia to Norfolk
PLN 112+
- Philadelphia to Burlington Bus
PLN 450+
Continue by bus from Knoxville
- Chattanooga to Atlanta Bus
PLN 107+
- Chattanooga to Nashville
PLN 100+
- Clarksville to Nashville
PLN 68+
- Jackson to Nashville Bus
PLN 182+
- Knoxville to Washington D.C. Bus
PLN 324+
- Knoxville to Atlanta Bus
PLN 219+
- Knoxville to Indianapolis
PLN 482+
- Knoxville to Charlotte Bus
PLN 565+
- Bus from Knoxville to New York
PLN 450+
- Knoxville to Chattanooga Bus
PLN 101+
- Bus from Knoxville to Memphis
PLN 553+
- Knoxville to Nashville Bus
PLN 183+
- Bus from Memphis to Atlanta
PLN 373+
- Memphis to Nashville
PLN 244+
- Bus from Murfreesboro to Atlanta
PLN 212+
- Bus from Murfreesboro to Nashville
PLN 39+
- Bus from Nashville to Atlanta
PLN 181+
- Nashville to Memphis Bus
PLN 183+
Check out these popular routes
- Bus from Calgary to Edmonton
PLN 91+
- Bus from Edmonton to Calgary
PLN 88+
- Bus from Vancouver to Seattle
PLN 215+
- Toronto to Ottawa Bus
PLN 116+
- Montreal to New York Bus
PLN 368+
- Bus from Washington D.C. to Philadelphia
PLN 60+
- Bus from Atlanta to New York
PLN 620+
- Boston to New York
PLN 103+
- Brooklyn to Philadelphia
PLN 33+
- Bus from New York to Montreal
PLN 364+
- Bus from New York to Washington D.C.
PLN 94+
- Bus from New York to Boston
PLN 105+
- Bus from New York to Buffalo
PLN 150+
- Bus from New York to Philadelphia
PLN 66+
- Bus from New York to Providence
PLN 114+
- Bus from Philadelphia to New York
PLN 68+
- Bus from Providence to New York
PLN 120+
- Seattle to Vancouver Bus
PLN 195+

Wanderu is the simplest way to book bus and train travel.
With just a quick search on Wanderu, you can compare bus and train schedules and prices from hundreds of travel companies in one convenient place to find the trip that works best for you. Wanderu’s simple checkout process makes it easy to book cheap bus and train tickets hassle-free. Most importantly, as Wanderu is an official partner of all leading bus and train companies, we always have the best bus and train deals out there.
- Bus Tickets
- United States
- Tennessee
- Knoxville
- Philadelphia to Knoxville






